ORIGINAL RESEARCH article
Front. Cardiovasc. Med.
Sec. Hypertension
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1361273
Knowledge, Attitudes, and Practices Regarding the Prevention of Intracerebral hemorrhage among Hypertensive Patients
Provisionally accepted- 1Department of Neurosurgery, Third Affiliated Hospital of Nantong University, Nantong, China
- 2Department of Neurosurgery, Dongtai People's Hospital, Dongtai, China
- 3Department of Emergency, Nantong Third People's Hospital, Affiliated Nantong Hospital 3 of Nantong University, Nantong, China
- 4Nantong Tumor Hospital, Nantong, China
- 5Department of Emergency, Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
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Objective: The present study aimed to assess knowledge, attitudes, and practices (KAP) regarding the prevention of intracerebral hemorrhage among hypertensive patients and medication adherence to hypertension.Methods: We conducted a cross-sectional study at the Third People's Hospital of Nantong City between November 4, 2023 and December 4, 2023. Demographic information, KAP and medication adherence scores were collected using an online questionnaire.Results: Totally 600 valid questionnaires were analyzed. Among these, 443 participants (73.83%) were female, with a mean age of 62.95 ± 15.07 years. The mean scores for knowledge, attitude, practice, and medication adherence were 13.93±2.88, 32.10±3.22, 25.53±3.44, and 3.12±1.85, respectively. Only 3.50% had high medication compliance to hypertension. Multivariate analyses revealed that uncertain about family history of hypertensive intracerebral hemorrhage (OR=0.378, 95%CI: [0.218-0.656]; P=0.001), no smoking (OR=4.603, 95%CI: [1.954-10.845]; P<0.001), and no alcohol consumption (OR=3.522, 95%CI: [1.764-7.033]; P<0.001) were independently associated with proactive practice. Structural equation modeling (SEM) results revealed direct effects between knowledge and attitude (β=0.999, P<0.001), knowledge and practice (β=1.103, P<0.001), as well as attitude and practice (β=0.452, P<0.001).Conclusion: Hypertensive patients demonstrated sufficient knowledge, positive attitudes, and inactive practices towards preventing intracerebral hemorrhage, coupled with poor medication adherence to hypertension. Developing targeted interventions to address these gaps and promoting a holistic approach is crucial to improving overall patient outcomes in clinical practice.
Keywords: knowledge, Attitude, Practice, Medication Adherence, Hypertension, intracerebral hemorrhage, Cross-sectional study
Received: 14 Jan 2024; Accepted: 19 May 2025.
Copyright: © 2025 Chen, Liu, Zhang, Jin and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Haibin Huang, Department of Emergency, Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
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