CASE REPORT article
Front. Cardiovasc. Med.
Sec. Thrombosis and Haemostasis
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1513776
This article is part of the Research TopicCase Reports in Thrombosis: 2025View all 12 articles
Application of AngioJet Thrombectomy System in acute lower extremity deep vein thrombosis complicated by transplanted renal vein thrombosis (report of 2 cases)
Provisionally accepted
- 1Shandong Second Medical University, Weifang, Shandong Province, China
- 2Weifang People's Hospital, Weifang, Shandong Province, China
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Lower extremity deep venous thrombosis (DVT) combined with transplanted renal vein thrombosis represents a rare and complex form of venous thromboembolism that leads to obstruction of the transplanted renal vein. This condition results in parenchymal edema of the kidney, ultimately impairing the function of the transplanted organ. It constitutes a catastrophic complication following renal transplantation, potentially resulting in loss of function of the transplanted kidney and failure of the surgical procedure. The primary objective of treatment is to promptly remove thrombi from the transplanted renal vein, thereby restoring normal venous return and renal function as swiftly as possible to enhance patient prognosis. Currently, surgical thrombectomy and thrombolytic therapy are considered mainstay treatment modalities. Surgical thrombectomy is generally recommended as a first-line approach due to its efficacy in achieving rapid thrombus removal. To date, there exists limited literature regarding the utilization of the AngioJet thrombectomy system for managing DVT in conjunction with transplanted renal vein thrombosis. In this report, we present two cases involving middle-aged male patients diagnosed with acute lower extremity DVT complicated by transplanted renal vein thrombosis. Both patients had undergone allogeneic kidney transplantation 15 years and 4 years prior, respectively. In these instances, we employed the AngioJet thrombectomy system for emergency thrombus aspiration treatment. The thrombi within both patients' lower extremity deep veins and their respective transplanted renal veins were completely removed. Subsequently, urine output gradually increased for both patients; moreover, their renal function progressively improved to an acceptable range. Notably, neither patient developed postoperative complications nor exhibited any recurrence of thrombus during follow-up evaluations.
Keywords: Transplanted renal vein thrombosis, Deep vein thrombosis (DVT), Kidney Transplantation, AngioJet thrombectomy system, Endovascular Therapy
Received: 19 Oct 2024; Accepted: 22 Aug 2025.
Copyright: © 2025 Shao, Cao, Shang, Sun, Ji, Zhang and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Tao Liu, Weifang People's Hospital, Weifang, 261000, Shandong Province, China
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