ORIGINAL RESEARCH article
Front. Cardiovasc. Med.
Sec. Coronary Artery Disease
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1547482
Comparing Three-Month and One-Year Patency Rates of No-Touch Great Saphenous Vein and Pedicled Left Internal Mammary Artery in Off-Pump Coronary Artery Bypass Grafting: A Prospective Non-Inferiority Study
Provisionally accepted
Teng-Yue ZhaoBing-Jie WangChu LiuJiang LiuJi-Qiang BuYu LiuShu-Guang ZhaoWen-Li Zhang
Zi-Ying Chen*Yu-Ming Wu- Second Hospital of Hebei Medical University, Shijiazhuang, China
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Objective: In this study, we compared the 3-month and 12-month patency rates of great saphenous vein (GSV) grafts harvested using the no-touch technique and pedicled left internal mammary artery (LIMA) in off-pump coronary artery bypass grafting (OPCABG). We also evaluated the short-term efficacy of the grafts harvested using the no-touch technique.Methods: A non-inferiority study was conducted between June 2019 and August 2022, involving 106 patients who underwent OPCABG using the "no-touch" technique to harvest grafts from the LIMA and GSV. We aimed to assess and compare the patency rates of the pedicled LIMA graft and the no-touch GSV graft at both the 3-month and 12-month postoperative intervals. Additionally, we sought to evaluate the advantages of employing the no-touch GSV graft in the context of OPCABG.Results: There was no statistically significant difference in patency between the no-touch GSV graft and the LIMA at 3 and 12 months post-OPCABG (P <0.001).The no-touch technique can provide graft patency comparability with the LIMA; therefore, in addition to the internal mammary artery, the no-touch GSV is recommended as a graft alternative.
Keywords: a non-inferiority study Teng-Yue Zhao1,2, MM, Bing-Jie Wang3, MM, Chu Liu1, MM, Jiang Liu1, MM, left internal mammary artery, Non-inferiority study, no-touch great saphenous vein, Off-pump coronary artery bypass grafting, rate of patency
Received: 18 Dec 2024; Accepted: 30 May 2025.
Copyright: © 2025 Zhao, Wang, Liu, Liu, Bu, Liu, Zhao, Zhang, Chen and Wu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Zi-Ying Chen, Second Hospital of Hebei Medical University, Shijiazhuang, China
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