ORIGINAL RESEARCH article
Front. Cardiovasc. Med.
Sec. Hypertension
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1572300
Previous abortion and preeclampsia in Kigali, Rwanda: a case-control study
Provisionally accepted
- 1Faculty of Medicine, University of Medical Science and Technology, Kigali, Rwanda, Kigali, Rwanda
- 2Department of Obstetrics and Gynecology, College of Medicine, Qassim University, Buraidah, Saudi Arabia, Buraidah, Saudi Arabia
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Objective: This study was conducted to investigate the association between previous spontaneous abortion and preeclampsia among pregnant women in Rwanda.Methods: A case (preeclampsia)-control (healthy pregnant women) study with 188 women per group was conducted at Kacyiru Hospital in Kigali, Rwanda. Data were collected using questionnaires, and multivariate binary analysis was performed.Results: There was no significant difference in age and parity between the case and control groups. In the case group, 29 (15.4%) and 13 (6.9%) women and 16 (8.5%) and 2 (1.1%) women in the control group had a history of one abortion or two or more abortions, respectively. A multivariate binary regression analysis revealed that women with a history of abortion had a higher risk of preeclampsia compared to their peers who had no history of abortion (adjusted odds ratio [AOR] = 2.66, 95% confidence interval [CI]: 1.35-5.27). Women with one past abortion (AOR = 2.33, 95% CI: 1.12-4.86) and those with two or more past abortions (AOR = 8.29, 95% CI: 1.73-39.63) had a higher risk of preeclampsia. Women with a history of preeclampsia who were rural residents or had an increasing body mass index showed a higher risk of preeclampsia. Conclusion: A history of abortion is associated with preeclampsia. Women with a history of abortion have to receive more frequent care, looking for the development of pre-eclampsia.
Keywords: spontaneous abortion, age, Preeclampsia, risk factor, Pregnancy
Received: 06 Feb 2025; Accepted: 26 Aug 2025.
Copyright: © 2025 Bakhiet, AlHabardi and Adam. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Nadiah AlHabardi, Department of Obstetrics and Gynecology, College of Medicine, Qassim University, Buraidah, Saudi Arabia, Buraidah, Saudi Arabia
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.