CASE REPORT article
Front. Cardiovasc. Med.
Sec. Thrombosis and Haemostasis
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1581930
This article is part of the Research TopicCase Reports in Thrombosis: 2025View all 6 articles
Paradoxical embolism caused by totally implantable venous access port: A case
Provisionally accepted
- First People's Hospital of Changzhou, Changzhou, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Totally implantable venous access ports (TIVAPs) are commonly used for patients undergoing chemotherapy and long-term repeated infusions. The incidence of thrombosis is low and rarely leads to serious complications. We report a case of right atrial thrombosis and paradoxical embolism in a 58-year-old male with atrial fibrillation (AF) and patent foramen ovale (PFO) 28 months after TIVAP implantation. The patient presented with dizziness and left limb weakness, subsequent diagnostic imaging revealed right temporal lobe infarction and a mass in the right atrium, who eventually recovered and was discharged after cardiac surgery and anticoagulation. This case highlights the rare but severe complication of right atrial thrombosis associated with TIVAP, particularly in patients with AF and PFO. Proper placement and timely removal of totally implantable venous access ports are crucial to minimize complications.Further research is needed to determine the necessity of anti-coagulation and PFO screening in patients with AF receiving central venous catheters.
Keywords: Totally implantable venous access port, Atrial Fibrillation, patent foramen ovale, Paradoxical embolism, Thrombosis
Received: 03 Mar 2025; Accepted: 14 Jul 2025.
Copyright: © 2025 Han, He, Chen and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Qi Wang, First People's Hospital of Changzhou, Changzhou, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.