ORIGINAL RESEARCH article
Front. Cardiovasc. Med.
Sec. Heart Failure and Transplantation
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1584894
The Relationship Between Right Ventricular Functions and Early Clinical Events During Hospitalization and After Discharge in Patients with Low Ejection Fraction Heart Failure
Provisionally accepted
- 1Istanbul Aydın University, Istanbul, Türkiye
- 2Antalya Research and Application Centre, Akdeniz University, Antalya, Antalya, Türkiye
- 3Faculty of Health Science, Istanbul Aydın University, Istanbul, Türkiye
- 4Palestine Polytechnic University, Hebron, Palestine
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The Relationship Between Right Ventricular Functions and Early Clinical Events During Hospitalization and After Discharge in Patients with Low Ejection Fraction Heart Failure Background and Aim: Right ventricular dysfunction is an independent predictor of poor prognosis in the patients with left ventricle failure. In this study, it is aimed to investigate the relationship between RV functions and early clinical events in hospital and after discharge in patients who were followed up for heart failure with a low ejection fraction and were hospitalized with the diagnosis of heart failure.Seventy patients with a left ventricular ejection fraction below 45% who were hospitalized due to decompensated heart failure were enrolled in this study.They were stabilized after medical treatment and discharged. Thereafter, they were followed up for 6 months in terms of clinical events. Image windows used as standard in the 2D echocardiography technique were recorded while the related technique was being performed.Results: Composite adverse events were observed in 45 patients (64.3%), while composite adverse events were not observed in 25 patients (35.7%). Relation between the independent risk factors and composite adverse events were analyzed with binary logistic regression analysis. Receiver Operating Characteristic (ROC) analysis was performed to determine the distinctive performance of right ventricular (RV) Global Longitudinal Strain (GLS) and RV Free Wall Strain (FWS) parameters in the prediction of mortality in patients.RV Global LS ( p<0.001) and RV Free W Strain (p<0.001) were determined as distinguishing factors related with mortality.We found that RV GLS and RV fwLS are closely related. Moreover, both measurements were correlated not only with parameters reflecting RV systolic function, but also with parameters reflecting LV function.
Keywords: left heart failure, right ventricle strain, diastolic dysfunction, Tissue Doppler echocardiography, Longitudinal 2d Strain Analysis, Speckle Tracking The Relationship Between Right Ventricular Functions and Early Clinical Events During Hospitalization and After Discharge in Patients with Low Ejection Fraction Heart Failure
Received: 27 Feb 2025; Accepted: 06 Jun 2025.
Copyright: © 2025 Onac, Kılınc, Huraibat, Al-ihribat and Dogan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Mehdi Onac, Istanbul Aydın University, Istanbul, 34295, Türkiye
Alaa R. Al-ihribat, Palestine Polytechnic University, Hebron, Palestine
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