CASE REPORT article
Front. Cardiovasc. Med.
Sec. Cardio-Oncology
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1586353
This article is part of the Research TopicCardiomyopathy and Heart Failure in OncologyView all 7 articles
Takotsubo Cardiomyopathy caused by acute surgical pathology against the background of colorectal cancer. Clinical case
Provisionally accepted
Vera Potievskaya1,2Victoria Khoronenko1,3Elena Kononova1Elena Paderina1
Zaki Fashafsha1,4*Andrey Kaprin1,3- 1P. Hertsen Moscow Oncology Research Institute – branch or the Federal State Budgetary Institution “National Medical Research Radiological Centre” of the Ministry of Health of the Russian Federation, Moscow, Moscow Oblast, Russia
- 2Russian Medical Academy of Postgraduate Education of Federal Scientific and Clinical Center for Specialized Medical Assistance and Medical Technologies of the Federal Medical Biological Agency,, Moscow, Moscow Oblast, Russia
- 3Peoples' Friendship University of Russia, Moscow, Moscow Oblast, Russia
- 4Institute for Personalized cardiology, I.M. Sechenov First Moscow State Medical University (Sechenov University),, Moscow, Russia
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We present a case of Takotsubo cardiomyopathy (TCM) in a young woman who has developed necrosis and perforation of the sigmoid intestine with a spontaneous opening of the abscess in the abdominal cavity, which caused purulent peritonitis. The patient underwent emergency surgical intervention. The postoperative period was complicated by a clinic of acute respiratory failure and bilateral pneumonia. In five days after surgery, the patient developed laboratory and instrumental signs of acute myocardial infarction. Changes similar to myocardial infarction appeared on electrocardiogram (ECG). Echocardiography revealed akinesis of the apical segments of the left ventricle and the ejection fraction of the left ventricle was reduced (LVEF) from 63 to 31 - 35%. The level of NT - proBNP has increased significantly, but the level of troponin I increased to a lesser extent. Coronary angiography demonstrated normal arteries without any obstruction. As a result, a diagnosis Takotsubo cardiomyopathy caused by acute surgical pathology was made. In the future, the patient was discharged in a stable state. Subsequent echocardiography showed normalization of the systolic function of the left ventricle, the disappearance of ECG changes, and a decrease in the level of specific cardiomarkers.
Keywords: Takotsubo syndrome, acute heart failure, Perioperative Period, Postoperative Complications, Sigmoid colon cancer
Received: 02 Mar 2025; Accepted: 16 Jul 2025.
Copyright: © 2025 Potievskaya, Khoronenko, Kononova, Paderina, Fashafsha and Kaprin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Zaki Fashafsha, Institute for Personalized cardiology, I.M. Sechenov First Moscow State Medical University (Sechenov University),, Moscow, Russia
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