CASE REPORT article
Front. Cardiovasc. Med.
Sec. Pediatric Cardiology
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1593438
This article is part of the Research TopicCase Reports in Clinical and Translational Cardiovascular Medicine: 2024View all 5 articles
Aveir implantation in an 8.7-year-old, 25-kg pediatric patient with mitochondrial disease via internal jugular vein
Provisionally accepted
- Children‘s Hospital of Chongqing Medical University, Chongqing, China
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Introduction: Mitochondrial disorders frequently precipitate progressive conduction system degeneration, with complete heart block representing a critical therapeutic challenge in pediatric populations, which ultimately requires permanent pacemaker implantation. However transjugular venous implantation of the Aveir leadless pacemaker in a pediatric patient with mitochondrial disease has not been previously reported. Methods and results: An 8.7-year-old, female patient (weight: 25kg) with genetically confirmed mitochondrial disease presented with cardiac syncope secondary to the complete atrioventricular block. Comorbidities included insulin-dependent diabetes and pocket infection from a conventional permanent pacemaker implanted four months prior. Given her history of device-related complications and restricted venous access, a retrievable leadless pacemaker (Abbott Aveir) was successfully implanted via the internal jugular vein under fluoroscopic guidance without complication. Stability testing confirmed adequate fixation with pacing threshold of 1.0V@0.2 ms and impedance of 610Ω at one-month follow-up. Conclusion: The Aveir VR leadless pacemaker can be safely implanted via the internal jugular vein approach in pediatric patients with mitochondrial disease.
Keywords: Aveir, pacing, transjugular venous, pediatric, mitochondrial disease
Received: 14 Mar 2025; Accepted: 12 Sep 2025.
Copyright: © 2025 Zhou, Xu, He, Liu and Lu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Tiewei Lu, ltw200145@163.com
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