ORIGINAL RESEARCH article
Front. Cardiovasc. Med.
Sec. Coronary Artery Disease
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1599313
This article is part of the Research TopicOptimizing Revascularization and Conservative Therapy in Chronic Coronary SyndromeView all 11 articles
The incidence of coronary in-stent restenosis and the rate of reaching the standard of low-density lipoprotein cholesterol in patients with type 2 diabetes mellitus and unstable angina pectoris treated with Ezetimibe and Rosuvastatin
Provisionally accepted
- Wenzhou People’s Hospital, Wenzhou, China
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Diabetes is closely associated with the occurrence and development of coronary atherosclerotic heart disease. Coronary atherosclerosis is often severe and diffuse in patients with diabetes. We investigated the incidence of coronary in-stent restenosis(ISR) and the rate of reaching the standard of low-density lipoprotein cholesterol (LDL-C) in patients with type 2 diabetes mellitus (T2DM) and unstable angina pectoris (UAP) treated with ezetimibe and rosuvastatin one year later.We selected the first pair of UAP patients with T2DM who underwent coronary artery stent implantation at our hospital between October 2018 and February 2022.According to drug use, the patients were divided into the rosuvastatin group (61 cases, rosuvastatin 10 mg/qn (every night)) and the combined group (60 cases, ezetimibe 10 mg/qd (once daily) and rosuvastatin 10 mg/qn). Biochemical indices, left ventricular ejection fraction, and left ventricular end-diastolic diameter were collected before and one year after the first percutaneous coronary intervention. We collected
Keywords: T2DM, unstable angina, In stent restenosis (ISR), ezetimibe, Rosuvasatin
Received: 24 Mar 2025; Accepted: 26 Aug 2025.
Copyright: © 2025 Ye, Li and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Hebo Li, Wenzhou People’s Hospital, Wenzhou, China
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