ORIGINAL RESEARCH article
Front. Cardiovasc. Med.
Sec. Coronary Artery Disease
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1600189
Yiqi Huoxue Tongluo Decoction Combined with Conventional Medicine Therapy: Effects on Restenosis Rate and Clinical Efficacy in Patients with Coronary Heart Disease Undergoing Percutaneous Coronary Intervention
Provisionally accepted
- 1Handan Mingren Hospital, Handan, China
- 2HanDan Central Hospital, Handan, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Objective: To investigate the effect of Yiqi Huoxue Tongluo Decoction (YHTD) combined with conventional medicine therapy on the restenosis rate and clinical efficacy of patients with coronary heart disease undergoing percutaneous coronary intervention.Methods: 80 patients with coronary artery disease after PCI between August 2019 and February 2021 were selected, and the patients were divided into the control group (n=40) and the observation group (n=40) according to the method of randomized numerical table. The control group received conventional medicine treatment, and the observation group took YHTD on the basis of conventional medicine treatment. Coronary angiography was reviewed after 6 months of treatment to compare the changes in coronary restenosis, TCM syndrome score, Seattle Angina Questionnaire (SAQ) score, cardiac function indexes and related serum biomarkers between the two groups.Results: After treatment, the TCM scores of patients in both groups were lower than those before treatment, and the post-treatment TCM scores of the observation group were significantly lower than those of the control group. After treatment, the SAQ scores of patients in both groups were significantly higher than those before treatment, and the SAQ scores of the observation group were significantly higher than those of the control group. The LVEDD and LVESD of both groups decreased after treatment compared with that before treatment, and the LVEDD and LVESD values of the observation group were significantly lower than those of the control group. At the same time, the LVEF and SV of patients in both groups increased compared with those before treatment, but the LVEF and SV values of the observation group were significantly higher than those of the control group, and the difference was statistically significant. After treatment, hs-CRP, Hcy and sST2 were significantly reduced in both groups, and the levels of hs-CRP, Hcy and sST2 in the observation group were significantly lower than those in the control group after treatment.
Keywords: the Chinese medicine Yiqi, blood circulation and collaterals soup Yiqi Huoxue Tongluo Decoction, conventional medicine therapy, percutaneous coronary intervention (PCI), restenosis (RS), Seattle Angina Questionnaire, cardiac function
Received: 26 Mar 2025; Accepted: 16 Jul 2025.
Copyright: © 2025 Zhao, Zhang and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Zhijie Liu, HanDan Central Hospital, Handan, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.