ORIGINAL RESEARCH article

Front. Cardiovasc. Med.

Sec. Heart Failure and Transplantation

Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1600223

This article is part of the Research TopicHeart Failure Induced by Non-Cardiac TherapiesView all articles

Analysis of Risk Factors and Application of Risk Management Strategies in Hemodialysis Patients Complicated with Heart Failure

Provisionally accepted
Guiren  HouGuiren HouFangzhou  HuangFangzhou HuangXi  FengXi FengSai  ChenSai Chen*
  • Changsha Fourth Hospital, Changsha, Hunan Province, China

The final, formatted version of the article will be published soon.

Background: Heart failure (HF) is a common and serious complication in maintenance hemodialysis (MHD) patients, significantly affecting their prognosis and quality of life. This study aims to identify risk factors for HF and evaluate targeted, risk-based nursing interventions.Methods: A total of 170 MHD patients admitted between January 2022 and January 2024 were divided into HF (n=80) and non-HF groups (n=90) based on the presence or absence of HF. Risk factors were analyzed using univariate and multivariate logistic regression. Subsequently, 80 HF patients were randomized to standard group (n=40) or study group receiving targeted risk management strategies (n=40). The intervention lasted 8 weeks and included comprehensive nursing measures based on individualized risk profiles. Outcome measures included Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS), complications, quality of life (SF-36), and nursing satisfaction.Results: Univariate analysis identified age (OR=1.076), dialysis duration (OR=1.054), hypertension (OR=3.391), diabetes (OR=2.874), coronary heart disease (OR=3.115), smoking history (OR=1.976), HbA1c (OR=18.675), and C-reactive protein (CRP; OR=1.466) as risk factors for HF in MHD patients (P<0.05). Multivariate logistic regression analysis confirmed age (OR=1.079), HbA1c (OR=20.371), and CRP (OR=1.542) as independent risk factors. After management, compared with the standard group, the study group showed significant reductions in SAS and SDS scores and complication incidence (P<0.05). The quality of life and nursing satisfaction significantly improved in the study group (P<0.05).Conclusion: Age, hyperglycemia, inflammation, and comorbidities (hypertension, diabetes, coronary heart disease) independently increase HF risk in MHD patients. Targeted risk management reduces psychological distress, complications, and enhances care outcomes.

Keywords: hemodialysis, Heart Failure, Risk factors, Risk management strategies, prognosis

Received: 26 Mar 2025; Accepted: 02 Jun 2025.

Copyright: © 2025 Hou, Huang, Feng and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Sai Chen, Changsha Fourth Hospital, Changsha, 410006, Hunan Province, China

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