ORIGINAL RESEARCH article
Front. Cardiovasc. Med.
Sec. Coronary Artery Disease
This article is part of the Research TopicCoronary Microcirculation: Diagnosis Treatment and Basic ResearchView all 4 articles
Cardiac Magnetic Resonance Characteristics and Risk Factors of Early Ventricular Aneurysm After Emergency Percutaneous Coronary Intervention in Acute Anterior Myocardial Infarction
Provisionally accepted
- 1The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China
- 2Division of Cardiology, Xiamen Cardiovascular Hospital, Xiamen University, Xiamen, Fujian Province, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Objectives: To investigate the cardiac magnetic resonance (CMR) features of early ventricular wall aneurysm formation in patients with acute anterior myocardial infarction. Methods: One hundred and eight patients with acute anterior myocardial infarction who underwent primary percutaneous coronary intervention and completed CMR scans within two weeks were retrospectively analyzed and divided into non-ventricular aneurysm group (n=72) and ventricular aneurysm group (n=36) according to whether they formed early ventricular aneurysms after surgery. Finally, the obtained CMR images were imported into software for image analysis, and a logistic regression analysis model was established to obtain CMR parameters for the diagnosis of early ventricular wall tumour. Results: Greater age and late gadolinium enhancement (LGE) and worse left heart function and myocardial strain in the ventricular wall aneurysm group than in the non-ventricular wall aneurysm group. LGE area (OR =1.32, 95% CI: 1.071-1.628, P=0.009), Apical angle (OR=1.24, 95% CI: 1.041-1.475, P=0.016), Septal mitral annular plane systolic excursion (Septal MAPSE, OR=0.36, 95% CI: 0.169-0.757, P=0.007) and Global longitudinal strain (GLS, OR=0.53, 95% CI: 0.154-0.953, P=0.046) were associated with early ventricular wall aneurysm formation. Finally, ROC curves were analyzed for the above four CMR parameters, and the AUC were obtained as 0.922, 0.921, 0.905, and 0.814; the optimal critical values were 28.5%, 90°, 8.245 mm, and 10.155%, respectively. Conclusions: Estimation of LGE area, Apical angle, Septal MAPSE and GLS using CMR technique in combination with software can help diagnose early ventricular wall aneurysm formation in patients with acute anterior myocardial infarction.
Keywords: Acute anterior myocardial infarction, cardiac magnetic resonance imaging, early ventricular aneurysm, magnetic resonance imaging parameter, Early detection
Received: 01 Apr 2025; Accepted: 28 Oct 2025.
Copyright: © 2025 wang, Lin, Wang, Zixuan and Hong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Qiao Hong, 18308122028@163.com
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.