CASE REPORT article
Front. Cardiovasc. Med.
Sec. Structural Interventional Cardiology
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1604387
Extracorporeal Membrane Oxygenation-supported One-stop Surgery for Transcatheter Aortic Valve Replacement and Percutaneous Coronary Intervention in High-risk Complex Coronary Artery and Aortic Valvular Disease: A Case Report
Provisionally accepted
- 1Jilin University, Changchun, China
- 2China-Japan Union Hospital, Jilin University, Changchun, Jilin Province, China
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Aortic stenosis (AS) is frequently associated with coronary artery disease (CAD), particularly in high-risk patients for whom treatment strategies lack standardized clinical guidelines. We report a case of a patient with severe AS and high-risk CAD, leading to significant heart failure, for whom surgical aortic valve replacement and coronary artery bypass grafting were unsuitable because of very high risk of morbidity and mortality. The patient underwent a one-stop procedure combining extracorporeal membrane oxygenation (ECMO)-assisted transcatheter aortic valve replacement (TAVR) and percutaneous coronary intervention (PCI). During the procedure, the patient first received preventive veno-arterial ECMO placement, successfully underwent PCI on the right coronary artery and left anterior descending artery, and then TAVR was performed without complications. The patient tolerated the procedure well, with hemodynamics remaining stable throughout. At one-year follow-up, the patient's heart function was significantly improved. This case provides valuable experience in treating high-risk AS combined with CAD, demonstrating the feasibility and effectiveness of this approach in clinical practice.
Keywords: transcatheter aortic valve replacement1, Extracorporeal membrane oxygenation2, Aortic stenosis3, Percutaneous coronary interventions4, Mechanical circulatory support5, case report6
Received: 01 Apr 2025; Accepted: 29 Aug 2025.
Copyright: © 2025 Zhang, Wang, Yu, Du, Zhang and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Guohui Liu, Jilin University, Changchun, China
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