ORIGINAL RESEARCH article

Front. Cardiovasc. Med.

Sec. General Cardiovascular Medicine

Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1606159

This article is part of the Research TopicCardiovascular care for patients with mental health and neurodevelopmental conditions: A focus on artificial intelligence and technologyView all articles

Multimodal AI-Driven Object Detection with Uncertainty Quantification for Cardiovascular Risk Assessment in Autistic Patients

Provisionally accepted
  • Sun Yat-sen University Cancer Center (SYSUCC), Guangzhou, China

The final, formatted version of the article will be published soon.

Artificial Intelligence (AI) has transformed medical diagnostics, offering enhanced precision and efficiency in detecting cardiovascular risks. However, traditional diagnostic approaches for cardiovascular risk assessment in autistic patients remain limited due to the complexity of medical data, inter-individual variability, and the challenges of integrating multi-modal clinical information.Conventional methods, relying heavily on manually extracted features and rule-based analysis, often fail to capture subtle cardiovascular abnormalities, leading to suboptimal clinical outcomes.To address these limitations, we propose an AI-driven object detection framework that leverages advanced deep learning techniques for automated, accurate cardiovascular risk assessment in autistic patients. Our approach integrates multi-modal medical data, including imaging and electronic health records, through a novel feature fusion mechanism, enhancing diagnostic precision. Furthermore, an uncertainty quantification module is embedded to improve model interpretability and reliability, addressing concerns regarding AI-based medical decision-making.Experimental evaluations demonstrate that our method significantly outperforms traditional diagnostic techniques in sensitivity and specificity, making it a robust tool for clinical applications.The proposed framework represents a significant step towards personalized and data-driven cardiovascular care for autistic patients, aligning with the need for tailored diagnostic solutions in this specialized medical domain.

Keywords: AI-Driven Diagnostics, Cardiovascular Risk Assessment, object detection, Multi-modal data fusion, uncertainty quantification

Received: 04 Apr 2025; Accepted: 16 May 2025.

Copyright: © 2025 Shen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Chengchao Shen, Sun Yat-sen University Cancer Center (SYSUCC), Guangzhou, China

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