CASE REPORT article
Front. Cardiovasc. Med.
Sec. Thrombosis and Haemostasis
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1608644
This article is part of the Research TopicAdvancements in Understanding and Managing Pulmonary Thromboembolism and HypertensionView all articles
Perhaps we can do more when Paradoxical Embolism meets thrombophilia: inspiration from a special case
Provisionally accepted
- 1Zhejiang Academy of Traditional Chinese Medicine, Hangzhou, China
- 2Department of Critical Care Units, Tongde Hospital of Zhejiang Province, Hangzhou, China
- 3Department of Cardiology, Tongde Hospital of Zhejiang Province, Hangzhou, China
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This study reported a rare case of Paradoxical Embolism complicated with thrombophilia. New thrombosis still existed after active treatment, and the existence of thrombus-prone gene was confirmed by gene detection. This patient recovered after improving the treatment plan. It emphasizes the importance of genetic testing to improve the diagnosis and treatment plan. This study comprehensively recorded the whole diagnosis and treatment process, including multidisciplinary collaboration, imaging diagnosis and personalized treatment strategies, which provided valuable guidance for similar clinical cases.
Keywords: Paradoxical embolism, Pulmonary Embolism, Acute cerebral infarction, Venous Thromboembolism, Plasminogen activator inhibitor-1
Received: 09 Apr 2025; Accepted: 22 Jul 2025.
Copyright: © 2025 Xue, Dai, Pang, 励, Ji, Meng and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Muhua Dai, Department of Critical Care Units, Tongde Hospital of Zhejiang Province, Hangzhou, China
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