REVIEW article
Front. Cardiovasc. Med.
Sec. Clinical and Translational Cardiovascular Medicine
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1613605
Mapping the research landscape of artificial hearts: Identifying hotspots and frontiers through bibliometric Analysis
Provisionally accepted
- 1Ningbo Zhenhai Hospital of Traditional Chinese Medicine, Ningbo, China
- 2The Rehabilitation Department of Wuhan No. 4 Hospital, Wuhan, Hebei Province, China
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The rising prevalence of advanced heart failure and the shortage of donor hearts underscore the need for artificial hearts. Technological evolution from pneumatic to magnetically levitated systems has occurred, yet critical challenges persist in hemocompatibility, anticoagulation, and transcutaneous energy transmission systems.We conducted a bibliometric analysis of 6,310 publications from the Web of Science Core Collection using CiteSpace, VOSviewer, and Bibliometrix. This study aimed to delineate research trends, collaboration patterns, and technological advancements in the artificial heart field.Results: Global publications showed a 13.9% average annual growth, with citations surging 260-fold.The USA leads research output, with China demonstrating rapid growth. Research focus has shifted from ventricular assist devices towards artificial intelligence control strategies. Magnetic levitation continuous-flow total artificial hearts and soft TAHs emerge as key technological innovations. Frontier research includes biohybrid systems and transcutaneous wireless power transfer.Artificial heart research displays a three-stage progression: clinical need-driven, technology integration, and intelligent innovation. Enhanced interdisciplinary collaboration is vital to address persistent challenges in biocompatibility optimization and personalized anticoagulation. This is crucial for transitioning the treatment paradigm from mechanical replacement towards physiologically adaptive, long-term solutions.
Keywords: Artificial heart, Bibliometrics, Biomaterials, artificial intelligence, Cardiovascular Medicine
Received: 17 Apr 2025; Accepted: 18 Jun 2025.
Copyright: © 2025 Peng, Peng and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Luyao Li, Ningbo Zhenhai Hospital of Traditional Chinese Medicine, Ningbo, China
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