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CASE REPORT article

Front. Cardiovasc. Med.

Sec. Heart Failure and Transplantation

Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1620302

This article is part of the Research TopicTransforming Care in Heart Failure and Cardiomyopathies: Emerging Insights and TreatmentsView all 9 articles

Left bundle branch area pacing in cardiac resynchronization therapy increases conduction velocity

Provisionally accepted
  • 1Aerospace Clinical Medical College of Peking University, Beijing, China
  • 2Peking University Health Science center, Beijing, China

The final, formatted version of the article will be published soon.

Several studies have suggested that the application of left bundle branch area pacing (LBBAP) in cardiac resynchronization therapy (CRT) holds promise as a treatment modality for correcting left bundle branch block (LBBB) while concurrently enhancing left ventricular structure and function (1,2). However, it's noteworthy that current guidelines do not provide specific recommendations for the use of left bundle branch area pacing, underscoring the need for additional evidence regarding its safety and efficacy(3,4). In this context, we present a case report detailing the utilization of LBBAP-CRTD treatment in a patient with LBBB-induced cardiomyopathy. The investigation encompasses a thorough examination of the efficacy and safety of LBBAP-CRTD, with a particular emphasis on cardiac synchronization parameters. Written consent was obtained from the patient, and this case report adheres to the CARE guideline (5).

Keywords: Cardiac Resynchronization Therapy, left bundle branch area pacing, Left bundle branch block, LBBB-induced cardiomyopathy, Heart Failure

Received: 29 Apr 2025; Accepted: 10 Sep 2025.

Copyright: © 2025 Zhang, Wang, He and Ding. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Chunhua Ding, dingmd@gmail.com

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