CASE REPORT article
Front. Cardiovasc. Med.
Sec. Coronary Artery Disease
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1633562
This article is part of the Research TopicCase Reports in Coronary Artery Disease: 2025View all 15 articles
Case Report: The Aslanger Pattern as an Indicator of Severe Acute Coronary Syndrome
Provisionally accepted
- 1Guangzhou University of Chinese Medicine, Guangzhou, China
- 2Guangzhou University of Traditional Chinese Medicine First Affiliated Hospital, Guangzhou, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Current guidelines categorize acute coronary syndrome (ACS) into unstable angina, ST-segment elevation myocardial infarction (STEMI), and non-ST-segment elevation myocardial infarction (NSTEMI). However, this categorization paradigm can lead to the underrecognition of acute coronary occlusion (ACO), especially when electrocardiographic findings are atypical. The Aslanger pattern is a critical ECG signature characterized by isolated ST-segment elevation in lead III with concomitant ST depression in leads V4-V6. It is often associated with severe multivessel disease, poor prognosis, and high mortality. We present two cases of chest pain with ECGs consistent with the Aslanger pattern. Coronary angiography confirmed three-vessel disease, with ACO in at least one vessel and severe stenosis in another. Notably, Patient 1 suffered in-hospital mortality, while Patient 2 had an uneventful recovery, underscoring the impact of timely intervention. This report emphasizes the value of recognizing the Aslanger pattern to bridge a diagnostic gap in ACS, enabling early identification of ACO, prompt reperfusion therapy, and ultimately, improved patient outcomes.
Keywords: Aslanger pattern, Acute Coronary Syndrome, Acute coronary occlusion, Percutaneous Coronary Intervention, case report
Received: 27 May 2025; Accepted: 09 Oct 2025.
Copyright: © 2025 Chen, Yao, Lin, Luo, Li and Zhao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xinjun Zhao, zxjhwxm@sina.com
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.