ORIGINAL RESEARCH article
Front. Cardiovasc. Med.
Sec. Lipids in Cardiovascular Disease
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1634134
Patterns and characteristics of dyslipidemia subtypes among community-dwelling elderly in Eastern China: A Cross-Sectional Study
Provisionally accepted
Xiaomeng Mi1*
Suting Xiong1Wenguo Xu1Fang Yao1Jie Huang2Lan Cui3Yu Qin3Jian Su3Wenchao Xu1Ran Tao3
Jinyi Zhou3- 1Changzhou Center for Disease Control and Prevention, Changzhou, China
- 2Nantong Center for Disease Control And Prevention, Nantong, China
- 3Jiangsu Provincial Center for Disease Control And Prevention, Nanjing, China
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Background Identifying and understanding different dyslipidemia patterns is crucial for maintaining the cardiovascular health of older adults. Therefore, this study aimed to investigate the dyslipidemia profiles of the elderly population from communities in an Eastern Chinese province, focusing on dyslipidemia subtypes and patterns, and exploring the associated demographic and health-related factors.A cross-sectional survey was conducted in communities in an Eastern Chinese province. Dyslipidemia patterns were defined using 4-digit binary codes for abnormal TC, TG, LDL-C, and HDL-C. Correspondence analysis explored subtypepattern associations to reveal common combinations. Binary and multinomial logistic regressions, with Bonferroni correction, examined relationships between factors and dyslipidemia patterns. Results Among 44,304 participants (31.5% dyslipidemia), correspondence analysis delineated patterns across Hyper_TC, Hyper_TG, Hyper_LDL, and Hypo_HDL subtypes, including Hyper_TC/LDL co-occurrence and Hyper_TG/Hypo_HDL independence, varying by gender. Multifactorial analyses revealed gender-based effects of age, education, income, and lifestyle, but consistent risks from comorbidities and urban-rural factors. Dyslipidemia subtype patterns and risk factor associations are thus gender-and pattern-specific.This study provided an in-depth analysis of dyslipidemia subtype patterns among community-dwelling elderly in Eastern China. The findings emphasized that considering gender-and pattern-specific risk factors is crucial in the prevention and management of dyslipidemia among older adults.
Keywords: Dyslipidemia, Dyslipidemia Subtypes, Dyslipidemia patterns, Community-dwelling elderly Chinese, gender differences
Received: 08 Jul 2025; Accepted: 04 Aug 2025.
Copyright: © 2025 Mi, Xiong, Xu, Yao, Huang, Cui, Qin, Su, Xu, Tao and Zhou. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xiaomeng Mi, Changzhou Center for Disease Control and Prevention, Changzhou, China
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