Your new experience awaits. Try the new design now and help us make it even better

ORIGINAL RESEARCH article

Front. Cardiovasc. Med.

Sec. Lipids in Cardiovascular Disease

Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1634134

Patterns and characteristics of dyslipidemia subtypes among community-dwelling elderly in Eastern China: A Cross-Sectional Study

Provisionally accepted
Xiaomeng  MiXiaomeng Mi1*Suting  XiongSuting Xiong1Wenguo  XuWenguo Xu1Fang  YaoFang Yao1Jie  HuangJie Huang2Lan  CuiLan Cui3Yu  QinYu Qin3Jian  SuJian Su3Wenchao  XuWenchao Xu1Ran  TaoRan Tao3Jinyi  ZhouJinyi Zhou3
  • 1Changzhou Center for Disease Control and Prevention, Changzhou, China
  • 2Nantong Center for Disease Control And Prevention, Nantong, China
  • 3Jiangsu Provincial Center for Disease Control And Prevention, Nanjing, China

The final, formatted version of the article will be published soon.

Background Identifying and understanding different dyslipidemia patterns is crucial for maintaining the cardiovascular health of older adults. Therefore, this study aimed to investigate the dyslipidemia profiles of the elderly population from communities in an Eastern Chinese province, focusing on dyslipidemia subtypes and patterns, and exploring the associated demographic and health-related factors.A cross-sectional survey was conducted in communities in an Eastern Chinese province. Dyslipidemia patterns were defined using 4-digit binary codes for abnormal TC, TG, LDL-C, and HDL-C. Correspondence analysis explored subtypepattern associations to reveal common combinations. Binary and multinomial logistic regressions, with Bonferroni correction, examined relationships between factors and dyslipidemia patterns. Results Among 44,304 participants (31.5% dyslipidemia), correspondence analysis delineated patterns across Hyper_TC, Hyper_TG, Hyper_LDL, and Hypo_HDL subtypes, including Hyper_TC/LDL co-occurrence and Hyper_TG/Hypo_HDL independence, varying by gender. Multifactorial analyses revealed gender-based effects of age, education, income, and lifestyle, but consistent risks from comorbidities and urban-rural factors. Dyslipidemia subtype patterns and risk factor associations are thus gender-and pattern-specific.This study provided an in-depth analysis of dyslipidemia subtype patterns among community-dwelling elderly in Eastern China. The findings emphasized that considering gender-and pattern-specific risk factors is crucial in the prevention and management of dyslipidemia among older adults.

Keywords: Dyslipidemia, Dyslipidemia Subtypes, Dyslipidemia patterns, Community-dwelling elderly Chinese, gender differences

Received: 08 Jul 2025; Accepted: 04 Aug 2025.

Copyright: © 2025 Mi, Xiong, Xu, Yao, Huang, Cui, Qin, Su, Xu, Tao and Zhou. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Xiaomeng Mi, Changzhou Center for Disease Control and Prevention, Changzhou, China

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.