CASE REPORT article
Front. Cardiovasc. Med.
Sec. Cardiovascular Imaging
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1637403
This article is part of the Research TopicRevolutionizing Cardiovascular Diagnosis: Advances in Functional Imaging TechnologiesView all 11 articles
PET-CT ischemia and viability maps guiding an emergency revascularization
Provisionally accepted
Dionysios Adamopoulos1,2,3*
Leo Meyer de Stadelhofen4*
François Mach1,3Valentina Garibotto3,5Stephane Noble1,3- 1Hopitaux Universitaires Geneve Service de cardiologie, Geneva, Switzerland
- 2Hopitaux Universitaire Geneve Service de Médecine nucleaire, Geneve, Switzerland
- 3Universite de Geneve, Geneva, Switzerland
- 4Hopitaux Universitaires Geneve Service de Médecine de premier recours, Geneve, Switzerland
- 5Hopitaux Universitaires Geneve Service de Medecine nucleaire, Geneve, Switzerland
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Abstract A 60-year-old woman was scheduled for elective coronary angiography after a positron emission tomography and computer tomography (PET-CT) cardiac perfusion imaging test showing extensive myocardial ischemia. A few hours before the scheduled angiography, she presented to the emergency room with chest pain and diffuse ST-segment modifications leading to emergent coronary angiography. Recent PET-CT ischemia and viability maps were available at the time of the intervention, favoring a percutaneous coronary intervention for chronic total occlusion (CTO PCI) of the left circumflex artery, apart from the culprit lesion of the left main coronary artery and left anterior descending artery, with good results. A second PET-CT scan 23 days post-PCI showed a reversible perfusion defect of the first diagonal branch territory, which was subsequently treated. A rapid normalization of the left ventricular ejection fraction (LVEF) was noted after revascularization, while the second PET-CT showed no signs of significant myocardial necrosis. This case illustrates the potential role of cardiac imaging perfusion studies in guiding revascularization in complex cases in the context of an acute myocardial infarction (MI).
Keywords: Nuclear cardiac imaging, Coronary Artery Disease, myocardial viability, CTO - percutaneous coronary intervention, Myocardial Ischemia
Received: 29 May 2025; Accepted: 09 Oct 2025.
Copyright: © 2025 Adamopoulos, Meyer de Stadelhofen, Mach, Garibotto and Noble. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Dionysios Adamopoulos, dionysios.adamopoulos@hcuge.ch
Leo Meyer de Stadelhofen, leo.meyer.de.stadelhofen@gmail.com
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.