CASE REPORT article
Front. Cardiovasc. Med.
Sec. Structural Interventional Cardiology
This article is part of the Research TopicTranscatheter Valve Interventions in Heart Failure: Emerging Strategies and OutcomesView all articles
Right Ventricular Apical Thrombus Formation After Transcatheter Edge-to-Edge Mitral Valve Repair: A Case Report
Provisionally accepted
- 1Suzhou Municipal Hospital, Suzhou, China
- 2The First Affiliated Hospital With Nanjing Medical University, Nanjing, China
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Transcatheter edge-to-edge repair is an alternative therapy for patients with severe mitral regurgitation. Here, we report the first case of right ventricular apical thrombus formation following transcatheter edge-to-edge repair in a 54-year-old male with heart failure and reduced ejection fraction. Post-procedural transthoracic echocardiography revealed multiple apical right ventricular thrombi on postoperative day 2. Anticoagulation with warfarin and low-molecular-weight heparin resulted in thrombus resolution, and the patient was discharged uneventfully. This case highlights the importance of vigilant postoperative monitoring and tailored thromboprophylaxis in patients with impaired ventricular function.
Keywords: Transcatheter edge-to-edge repair (TEER), right ventricular apical thrombosis, Anticoagulant treatment, severe mitral regurgitation, Heart Failure
Received: 03 Jun 2025; Accepted: 24 Nov 2025.
Copyright: © 2025 Cai, Zhang, Gou and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Haifeng Zhang
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