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CASE REPORT article

Front. Cardiovasc. Med.

Sec. Coronary Artery Disease

Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1640534

This article is part of the Research TopicCase Reports in Coronary Artery Disease: 2025View all 10 articles

Case Report: Anomalous Origin of the Left Main Coronary Artery from the Left Ventricular Outflow Tract

Provisionally accepted
Minh Thuy  Thi HuynhMinh Thuy Thi Huynh1,2Bao Luan  Minh TranBao Luan Minh Tran2,3*Tuan Anh  Tho PhamTuan Anh Tho Pham3Dinh  Hoang NguyenDinh Hoang Nguyen2,3
  • 1Tam Anh Hospital, Ho Chi Minh City, Vietnam
  • 2University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam
  • 3University Medical Center at Ho Chi Minh City, Ho Chi Minh, Vietnam

The final, formatted version of the article will be published soon.

Anomalous origin of the left main coronary artery from the left ventricular outflow tract is an exceedingly rare congenital coronary anomaly, typically associated with impaired myocardial perfusion. We report the case of a 67-year-old asymptomatic woman in whom an anomalous origin of the left main coronary artery, arising from the left ventricular outflow tract below the aortic valve, was incidentally identified during routine preoperative cardiac evaluation. Despite the anatomical abnormality, the patient exhibited no clinical or imaging evidence of myocardial ischemia. This finding is likely explained by marked dilation of the right coronary artery and the presence of welldeveloped collateral circulation supplying the left coronary system. With no evidence of ischemia and maintained ventricular function, a non-interventional approach was deemed appropriate. This case highlights the importance of comprehensive anatomical and functional assessment in detecting clinically silent coronary anomalies and underscores the value of advanced cardiac imaging in the preoperative evaluation of elderly patients undergoing non-cardiac procedures.

Keywords: Congenital coronary artery, Left main coronary artery, Anomalous origin of the coronary artery, Coronary computed tomography angiography, Coronary Angiography

Received: 03 Jun 2025; Accepted: 22 Jul 2025.

Copyright: © 2025 Huynh, Tran, Pham and Nguyen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Bao Luan Minh Tran, University Medical Center at Ho Chi Minh City, Ho Chi Minh, Vietnam

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