REVIEW article
Front. Cardiovasc. Med.
Sec. Cardiovascular Surgery
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1645705
Physiologic effects of different hemodynamic patterns of LVAD
Provisionally accepted
- 1Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Chaoyang District, China
- 2Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China
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Left ventricular assist device (LVAD) is an important treatment for patients with end-stage heart failure, which essentially replaces the left ventricle's pumping action to improve peripheral circulation. Its hemodynamic pattern (pulsatile versus continuous flow) has been a popular research topic in the field. Because of its dependability and endurance, the continuous flow LVAD (CFVAD), as opposed to the first generation of pulsatile flow LVAD (PFVAD), has gained popularity as a mechanical support device in clinical practice in recent years. Many of the complications that arise with CFVAD application are thought to be related to reduced pulsatility. This article provides a review of the physiologic effects of different hemodynamic patterns on the circulatory system and the difference in outcomes of PFVAD versus CFVAD.
Keywords: Pulsatile Flow, continuous flow, left ventricular assist device (LVAD), Heart Failure, Pulsatility
Received: 12 Jun 2025; Accepted: 17 Jul 2025.
Copyright: © 2025 Mao, Gao, Yu and Yu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yang Yu, Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Chaoyang District, China
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