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CORRECTION article

Front. Cardiovasc. Med.

Sec. Cardiovascular Genetics and Systems Medicine

Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1662054

Correction: Comprehensive Analysis of the Transcriptome-Wide m6A Methylome of Heart via MeRIP After Birth: Day 0 vs. Day 7

Provisionally accepted
  • 1School of Medicine, Southeast University, Nanjing, China
  • 2The First Affiliated Hospital With Nanjing Medical University, Nanjing, China

The final, formatted version of the article will be published soon.

Correction on: Yang C, Zhao K, Zhang J, Wu X, Sun W, Kong X and Shi J (2021) Comprehensive Analysis of the Transcriptome-Wide m6A Methylome of Heart via MeRIP After Birth: Day 0 vs. Day 7. Front. Cardiovasc. Med. 8:633631. doi: 10.3389/fcvm.2021.633631 In the published article, there was an error in Figure 1C and Figure 8A as published. Due to our mistake in combining images, GAPDH band in Figures 1C, and images for NRCMs staining in Figure 8A were misused. The corrected Figure 1C and Figure 8A appear below. The level of m6A in P7 rat heart was decreased compared to P0. (A, B) Representative immunofluorescence images of paraffin-embedded heart sections labeled with α-Actinin, Ki67,pH3,Aurora B,green;Ki67,pH3,Aurora B,and EDU,red;DAPI,blue. Scale bars,200 µm). (C, D) Protein expression levels of PCNA as determined by Western blotting (C) in heart tissue from P0 and P7 rats and the corresponding densitometric analyses (D). GAPDH was detected as the loading control. (E, F) Quantification of m6A in total RNA in heart tissue (E) and NRCMs (F) from P0 and P7 rats. N 3 per group. The results are expressed as means ± SEMs (NS indicates not significant, *P 0.05, **P 0.01, ***P 0.001, compared to the control group). (I), and Pfkfb2 (J) in P0 NRCMs transfected with si-NC or si-METTL3 after treated with 20µg/ml Actinomycin D for 0, 3 or 6 hours. (K) Protein expression levels of Dhcr24, Nacad, Slc16a3, and Slc7a5 in P0 NRCMs transfected with si-NC or si-METTL3 (up) and the corresponding densitometric analysis (down). (L-O) mRNA expression level of Dhcr24 (L), Nacad (M), Slc16a3 (N), and Slc7a5 (O) in P0 NRCMs transfected with si-NC or si-METTL3 after treated with 20 µg/ml Actinomycin D for 0, 3 or 6 h. GAPDH was detected as the loading control. *P 0.05, **P 0.01, ****P 0.001, *****P 0.0001, compared to the si-NC group.The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated. In the published article, there was an error in Supplementary Figure 1. Due to our oversight during the review process, Supplementary Figure 1 did not use the latest images we revised back when the article was typesetting. The correct material statement appears below.

Keywords: M6A, epitranscriptome, heart regeneration, METTL3, cardiomyocyte

Received: 08 Jul 2025; Accepted: 11 Aug 2025.

Copyright: © 2025 Yang, Zhao, Zhang, Wu, Sun, Kong and Shi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Xiangqing Kong, The First Affiliated Hospital With Nanjing Medical University, Nanjing, China
Jing Shi, The First Affiliated Hospital With Nanjing Medical University, Nanjing, China

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