REVIEW article
Front. Cardiovasc. Med.
Sec. Cardiac Rhythmology
Volume 12 - 2025 | doi: 10.3389/fcvm.2025.1679578
This article is part of the Research TopicPrecision Strategies for Atrial Fibrillation: Diagnosis, Risk, and Treatment InnovationsView all articles
Pulsed Field Ablation for Atrial Fibrillation: Clinical Applications and Research Advances
Provisionally accepted
- 1First Hospital of Shanxi Medical University, Taiyuan, China
- 2Shanxi Medical University, Taiyuan, China
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Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, associated with increased risks of stroke, heart failure, and mortality. With the advancement of catheter ablation technology, pulsed field ablation (PFA), a novel nonthermal ablation modality, has garnered growing attention due to its myocardial selectivity and favorable safety profile. This review systematically summarizes the biophysical principles, clinical advantages, catheter systems, special population applications, limitations, and future directions of PFA based on the latest evidence.
Keywords: Atrial Fibrillation, pulsed field ablation, Irreversible electroporation, Pulmonary vein isolation, Myocardial selectivity, Safety, Emerging Technologies
Received: 04 Aug 2025; Accepted: 25 Aug 2025.
Copyright: © 2025 Wang, Sun, Fu, Gao, Guo and Yin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Rui Wang, First Hospital of Shanxi Medical University, Taiyuan, China
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