ORIGINAL RESEARCH article
Front. Cardiovasc. Med.
Sec. Pediatric Cardiology
This article is part of the Research TopicSurgical and Non-Surgical Intervention of Congenital Heart Disease Management in Developing and Developed CountriesView all 17 articles
The Landscape of Management and Outcome of Children with Congenitally Corrected Transposition of the Great Arteries: A Single Center Experience
Provisionally accepted
Yazeed Saleh Alahmed1,2,3,4
Abdulraouf M.Z Jijeh2,4,5Abdulsalam M Alsaiad2,4,5T. Mesud Yelbuz2,4,5Mohamed S Kabbani2,4,5Abdullah A Alghamdi2,4,5Fahad Alhabshan2,4,5Ibrahim J Alibrahim2,4*- 1Department of Pediatric, College of Medicine, Qassim University, Buraidah, Saudi Arabia
- 2Department of Cardiac Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia
- 3Department of Cardiology, Qassim University Medical City, Al Mulayda, Saudi Arabia
- 4King Abdullah International Medical Research Center, Riyadh, Saudi Arabia
- 5King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia
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Objective: To compare the outcomes in patients with congenitally corrected transposition of the great arteries (ccTGA) who were offered different surgical management strategies. Design and Settings: We retrospectively included all patients from our centre diagnosed with ccTGA between 2000 and 2021. The cohort was divided into four groups: (1) Patients with systemic right ventricle; (2) Patients with anatomic repair (in form of an atrial and arterial switch, or atrial switch and Rastelli operation); (3) Patients with one and a half ventricle repair (hemi-Mustard type) and bidirectional cavopulmonary connection and placement of right ventricle to pulmonary artery conduit; and (4) Patients with single ventricle who were not suitable for biventricular repair. Results: The study included 42 patients with ccTGA. In thirty-nine patients (93%), ccTGA was associated with other congenital heart defects. Group 1 (systemic right ventricle) had 16 patients (38%); seven of them underwent pulmonary artery banding, with improvement in tricuspid valve regurgitation in four patients. Group 2 (anatomic group) and Group 3 (one and a half ventricle group) each had three patients (7%). Group 4 (Single ventricle palliation) consisted of 17 patients (40%); 15 of them (88%) completed total cavopulmonary connection (TCPC). Three early mortalities (7%) were recorded. Conclusions: Patients who underwent anatomical repair (Rastelli type) or one and a half ventricle repair (hemi-Mustard type) showed a good outcome with satisfactory biventricular function. Moreover, single ventricle palliation showed excellent mid-term results in patients with ccTGA. PA banding may improve the TR in patients with ccTGA. Follow-up of our managed patients by an individualized plan demonstrated satisfactory outcomes.
Keywords: congenitally corrected transposition of great arteries (CCTGA), Single ventricle palliation, Pulmonary artery band, one and a half ventricle, Rastelli operation
Received: 09 Aug 2025; Accepted: 19 Nov 2025.
Copyright: © 2025 Alahmed, Jijeh, Alsaiad, Yelbuz, Kabbani, Alghamdi, Alhabshan and Alibrahim. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Ibrahim J Alibrahim, ibrahimi2@mngha.med.sa
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