ORIGINAL RESEARCH article
Front. Cardiovasc. Med.
Sec. Cardiovascular Imaging
Fractal analysis of left ventricular trabeculae in hypertensive patients with heart failure: a 3.0 T cardiac magnetic resonance study
Provisionally accepted
- 1Second Affiliated Hospital of Nanchang University, Nanchang, China
- 2Zhengzhou University, Zhengzhou, China
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Abstract Background: Endocardial trabecular hyperplasia due to hemodynamic stress reflects phenotypic variability in disease progression. Employing fractal analysis, this study quantified left ventricular (LV) myocardial trabecular complexity in hypertensive patients with and without heart failure (HF) to evaluate its diagnostic utility for HF. Methods: This study retrospectively enrolled 146 hypertensive patients (77 with HF, 69 without), grouped into HTN-HF (n=77) and HTN non-HF (n=69); additionally, 34 healthy controls were recruited. Clinical data and cardiac MRI parameters were compared. Fractal dimension (FD) values were calculated on the LV short-axis cine images using fractal analysis. Logistic regression analysis was performed to determine predictors. Results:
Keywords: Heart Failure, Hypertension, Left ventricular myocardial trabecular, fractal analysis, magnetic resonance imaging.
Received: 15 Sep 2025; Accepted: 30 Oct 2025.
Copyright: © 2025 Xie, Zhao, Deng, Ren, Yu, Feng, Zhang, Gong and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Lianggeng Gong, gong111999@126.com
Hui Liu, liuhuiimage@qq.com
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