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REVIEW article

Front. Cardiovasc. Med.

Sec. Cardiac Rhythmology

This article is part of the Research TopicManagement of Arrhythmias in Acute and Intensive Care SettingsView all articles

The Potential Role of Stellate Ganglion Block in Impacting the Central and Peripheral Systems: A Narrative Review

Provisionally accepted
  • First Hospital of Jiaxing, Jiaxing, China

The final, formatted version of the article will be published soon.

To explore the potential benefits of Stellate ganglion block (SGB) in regulating the central and peripheral systems, as well as its potential as a treatment option for these diseases. We conducted a comprehensive search in PubMed, Web of Science, and Google Scholar libraries using the following keywords: stellate ganglion block, sympathetic nervous system, cardiovascular diseases, cerebrovascular diseases, and perioperative stress response. We selected and critically reviewed research articles published in English related to SGB modulation for the treatment of central and peripheral disease. The collected literature was classified according to content and reviewed in combination with experimental results and clinical cases. SGB can help regulate the cardiovascular and cerebrovascular systems by blocking sympathetic signals, reducing overactivation of the sympathetic nervous system linked to cardiovascular diseases. This local nerve block technique could be a treatment option for these conditions.

Keywords: Stellate ganglion block, Sympathetic Nervous System, Cardiovascular Diseases, cerebrovascular diseases, perioperative stress response

Received: 16 Sep 2025; Accepted: 07 Nov 2025.

Copyright: © 2025 Zhang and An. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Mingzi An, anmingzizi@163.com

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