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CASE REPORT article

Front. Cardiovasc. Med.

Sec. General Cardiovascular Medicine

Hypertrophic cardiomyopathy meets left ventricular hypertrabeculation: from mixed cardiomyopathy to hypertrophic cardiomyopathy with hypertrabeculation

Provisionally accepted
Yang  LiYang Li1Yang  LiuYang Liu1Xiaofei  ZhengXiaofei Zheng2Lijuan  ChenLijuan Chen1Qiming  DaiQiming Dai1*Genshan  MaGenshan Ma1
  • 1Southeast University Zhongda Hospital Department of Cardiology, Nanjing, China
  • 2Southeast University Zhongda Hospital Department of Radiology, Nanjing, China

The final, formatted version of the article will be published soon.

[Abstract] This case report refers a young male patient admitted due to worsened heart failure with recurrent embolic events. He was diagnosed with hypertrophic cardiomyopathy with left ventricular systolic dysfunction in other hospitals and was treated with irregular medications including betablocker and diuretics. This time, he was diagnosed with left ventricular myocardial noncompaction combined with hypertrophic cardiomyopathy by echocardiography and cardiac MR examination. Coexistence of left ventricular hypertrophy and hypertrabeculation is rare and diagnosis has been updated according to newly issued ESC guideline. Present report described the clinical features, therapy and outcome of this disease.

Keywords: left ventricular noncompaction/hypertrabeculation, Hypertrophic Cardiomyopathy, Heart Failure, cardiac MR, cardiomyopathy

Received: 18 Sep 2025; Accepted: 05 Nov 2025.

Copyright: © 2025 Li, Liu, Zheng, Chen, Dai and Ma. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Qiming Dai, 13815879581@qq.com

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