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ORIGINAL RESEARCH article

Front. Cardiovasc. Med.

Sec. Cardiovascular Nursing

Nutritional support contributes to improving cardiac function and nutritional status in atrial fibrillation patients receiving treatment with esmolol hydrochloride

Provisionally accepted
Xiaochao  LiuXiaochao Liu1Yulong  FanYulong Fan2Zhi  LiuZhi Liu1*
  • 1Department of Emergency, Xuanwu Hospital Capital Medical University, Beijing, China
  • 2Nerve Intervention Center, Capital Medical University affiliated Tongren Hospital Mentougou Hospital, Beijing, China

The final, formatted version of the article will be published soon.

Abstract Aim: This study focused on the effect of nutritional support combined with esmolol hydrochloride on the efficacy, nutritional status and quality of life of patients with atrial fibrillation (AF). Methods: This retrospective cohort study categorised patients into a treatment group (TG) and a nursing group (NG) based on whether they received a high-quality care model, spanning the period from February 2021 to February 2024. Both groups received treatment with esmolol hydrochloride. The TG received standard care, while the NG received enhanced care (nutritional intervention + skin care) in addition to standard care. The study compared efficacy, cardiac function, nutritional status, adverse reactions, care satisfaction, and quality of life between the two groups. Result: Each group included 93 patients. The clinical efficacy of esmolol hydrochloride treatment in AF patients exceeds 90%, with nutritional care showing no significant enhancement of clinical outcomes (P=0.249). However, compared to esmolol monotherapy, combined nutritional care intervention significantly reduced the length of hospitalisation, elevated Left ventricular ejection fraction (LVEF) levels, reduced Left ventricular systolic vector (LVESV) levels, and markedly improved nutritional indicators including Albumin (ALB), Total protein (TP), and Prognostic Nutritional Index (PNI). Furthermore, the combined intervention group demonstrated markedly improved nursing satisfaction and quality of life. Conclusion: Nutritional care administered alongside treatment with esmolol hydrochloride demonstrates superior efficacy in improving cardiac function, nutritional status, and quality of life among patients with AF.

Keywords: Esmolol hydrochloride, Atrial Fibrillation, Nutritional Support, Nursing Care, cardiac function, clinical efficacy

Received: 10 Oct 2025; Accepted: 20 Nov 2025.

Copyright: © 2025 Liu, Fan and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Zhi Liu, llzz14526@outlook.com

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