Frontiers in Cardiovascular Medicine | Cardiovascular Genetics and Systems Medicine

Original Research

Published on 16 Jul 2021

Uncovering Potential lncRNAs and mRNAs in the Progression From Acute Myocardial Infarction to Myocardial Fibrosis to Heart Failure

in Cardiovascular Genetics and Systems Medicine

Shuo Wang
Enmao Wang
Qincong Chen
Yan Yang
Lei Xu
Xiaolei Zhang
Rubing Wu
Xitian Hu
Zhihong Wu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.664044

6,445 views
15 citations

Original Research

Published on 15 Jul 2021

Contribution of Congenital Heart Disorders Associated With Copy Number Variants in Mediating Risk for Brain Developmental Disorders: Evidence From 20-Year Retrospective Cohort Study

in Cardiovascular Genetics and Systems Medicine

Luke Dowden
David Tucker
Sian Morgan
Orhan Uzun
Yasir Ahmed Syed

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.655463

2,912 views
7 citations

Original Research

Published on 12 Jul 2021

WNT3A rs752107(C > T) Polymorphism Is Associated With an Increased Risk of Essential Hypertension and Related Cardiovascular Diseases

in Cardiovascular Genetics and Systems Medicine

Huan Ren
Jian-Quan Luo
Fan Ouyang
Li Cheng
Xiao-Ping Chen
Hong-Hao Zhou
Wei-Hua Huang
Wei Zhang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.675222

3,847 views
12 citations

Original Research

Published on 02 Jul 2021

Analysis of Hub Genes and the Mechanism of Immune Infiltration in Stanford Type a Aortic Dissection

in Cardiovascular Genetics and Systems Medicine

Haoyu Gao
Xiaogang Sun
Yanxiang Liu
Shenghua Liang
Bowen Zhang
Luchen Wang
Jie Ren

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.680065

8,182 views
24 citations

Case Report

Published on 01 Jul 2021

Case Report: A Novel NKX2-5 Mutation in a Family With Congenital Heart Defects, Left Ventricular Non-compaction, Conduction Disease, and Sudden Cardiac Death

in Cardiovascular Genetics and Systems Medicine

Paula Morlanes-Gracia
Guido Antoniutti
Jorge Alvarez-Rubio
Laura Torres-Juan
Damian Heine-Suñer
Tomás Ripoll-Vera

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.691203

5,351 views
8 citations

Original Research

Published on 28 Jun 2021

Effect of Cytochrome P450 Family 2 Subfamily R Member 1 Variants on the Predisposition of Coronary Heart Disease in the Chinese Han Population

in Cardiovascular Genetics and Systems Medicine

Qi Wang
Zhen Lin
Hairong Chen
Tianyi Ma
Biyun Pan

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.652729

2,388 views
5 citations

Original Research

Published on 23 Jun 2021

Cardiomyocyte Proliferative Capacity Is Restricted in Mice With Lmna Mutation

in Cardiovascular Genetics and Systems Medicine

Kenji Onoue
Hiroko Wakimoto
Jiangming Jiang
Michael Parfenov
Steven DePalma
David Conner
Joshua Gorham
David McKean
Jonathan G. Seidman
Christine E. Seidman

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.639148

5,646 views
10 citations

Opinion

Published on 21 Jun 2021

Further Considerations in Childhood-Onset Hypertrophic Cardiomyopathy Genetic Testing

in Cardiovascular Genetics and Systems Medicine

Michelle M. Monasky
Emanuele Micaglio
Silvia Ignaccolo
Carlo Pappone

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.698078

1,868 views

Original Research

Published on 11 Jun 2021

Cardiac Dysfunction in a Mouse Vascular Dementia Model of Bilateral Common Carotid Artery Stenosis

in Cardiovascular Genetics and Systems Medicine

Lulu An
Michael Chopp
Alex Zacharek
Yi Shen
Zhili Chen
Yu Qian
Wei Li
Julie Landschoot-Ward
Zhongwu Liu
Poornima Venkat

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.681572

8,399 views
11 citations

Original Research

Published on 31 May 2021

A Functional Indel Polymorphism Within MIR155HG Is Associated With Sudden Cardiac Death Risk in a Chinese Population

in Cardiovascular Genetics and Systems Medicine

Qing Zhang
Huan Yu
Zhenzhen Yang
Lijuan Li
Yan He
Shaohua Zhu
Chengtao Li
Suhua Zhang
Bin Luo
Yuzhen Gao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.671168

3,195 views
3 citations

Original Research

Published on 31 May 2021

Identification of Potential miRNA-mRNA Regulatory Network Contributing to Hypertrophic Cardiomyopathy (HCM)

in Cardiovascular Genetics and Systems Medicine

Lin Wang
Fengmin Lu
Jing Xu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.660372

5,019 views
12 citations

Original Research

Published on 28 May 2021

Transcriptome and N6-Methyladenosine RNA Methylome Analyses in Aortic Dissection and Normal Human Aorta

in Cardiovascular Genetics and Systems Medicine

Xianwu Zhou
Zerui Chen
Jianrong Zhou
Yaorong Liu
Ruixin Fan
Tucheng Sun

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.627380

6,365 views
23 citations

Original Research

Published on 26 May 2021

Mutant Single Nucleotide Polymorphism rs189037 in Ataxia-Telangiectasia Mutated Gene Is Significantly Associated With Ventricular Wall Thickness and Human Lifespan

in Cardiovascular Genetics and Systems Medicine

Shihui Fu
Jianqiu Hu
Xiaoping Chen
Bo Li
Hongjuan Shun
Juelin Deng
Yujie Zhang
Yao Yao
Yali Zhao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.658908

2,478 views
15 citations

Original Research

Published on 21 May 2021

Knockdown of lncRNA ENST00000609755.1 Confers Protection Against Early oxLDL-Induced Coronary Heart Disease

in Cardiovascular Genetics and Systems Medicine

Yi Sun
Shuna Huang
Chunyu Wan
Qishuang Ruan
Xiaoxu Xie
Donghong Wei
Guobo Li
Shaowei Lin
Huangyuan Li
Siying Wu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.650212

2,968 views
5 citations

Original Research

Published on 20 May 2021

Phenotypic Variability of a Pathogenic PKP2 Mutation in an Italian Family Affected by Arrhythmogenic Cardiomyopathy and Juvenile Sudden Death: Considerations From Molecular Autopsy to Sport Restriction

in Cardiovascular Genetics and Systems Medicine

Maria Pia Leone
Pietro Palumbo
Johan Saenen
Sandra Mastroianno
Stefano Castellana
Cesare Amico
Tommaso Mazza
Domenico Rosario Potenza
Antonio Petracca
Marco Castori

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.635141

5,157 views
5 citations

Original Research

Published on 20 May 2021

Regulatory T Cell-Related Gene Biomarkers in the Deterioration of Atherosclerosis

in Cardiovascular Genetics and Systems Medicine

Meng Xia
Qingmeng Wu
Pengfei Chen
Cheng Qian

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2021.661709

6,342 views
21 citations