Frontiers in Cellular Neuroscience | Cellular Neuropathology

Original Research

Published on 12 Sep 2025

Establishment of human Leber’s hereditary optic neuropathy model using iPSC-derived retinal organoids

in Cellular Neuropathology

Kota Aoshima
Yuya Takagi
Michinori Funato
Yoshiki Kuse
Shinsuke Nakamura
Masamitsu Shimazawa

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1635775

428 views

Original Research

Accepted on 10 Sep 2025

Galactin-3 regulation of CDC42 promotes neuronal autophagy following spinal cord injury

in Cellular Neuropathology

Lei Yan
Xun Zhou
Qianqiu Li
Hongxiang Hong
Chunshuai Wu
Yong-Jing Gao
Guanhua Xu
Zhiming Cui

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1622825

136 views

Brief Research Report

Accepted on 10 Sep 2025

Brain-derived neurotrophic factor prevents LPS-induced dysregulation of GABAergic interneuron markers in mouse hippocampus

in Cellular Neuropathology

Sara Rezaei
Mounira Banasr
Thomas Prevot
Yashika Bansal
Erica Vieira
Etienne Sibille

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1675003

135 views

Review

Published on 10 Sep 2025

Alzheimer’s disease: where do we stand now and what are the strategic interventions?

in Cellular Neuropathology

Andrea González
Stephanie Geywitz
Ricardo B. Maccioni

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1655342

456 views

Review

Published on 10 Sep 2025

Schwann cells in the inner ear: development, disease, and regeneration

in Cellular Neuropathology

Drew J. Montigny
Judith S. Kempfle

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1662274

426 views

Original Research

Accepted on 08 Sep 2025

A Mutational Hotspot in TUBB2A Associated with impaired Heterodimer Formation and severe Brain Developmental Disorders

in Cellular Neuropathology

Gabriele Di Pasquale
Jacopo Colella
Carola Pia Di Cataldo
MIGUEL A. SOLER
Sara Fortuna
Emma Mizrahi-Powell
Mathilde Nizon
Benjamin COGNE
Valentina Turchetti
Giuseppe Mangano

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1664953

236 views

Methods

Published on 08 Sep 2025

A customized affordable multiplexed immunofluorescence method visualizes early changes in the mouse brain microenvironment upon laser cytoreduction

in Cellular Neuropathology

Santhosh Shanmugam Anandhan
Jeremy Spence
Farhana Begum
Nimrat Kaur
Dana Henderson
Sabine Hombach-Klonisch
Thomas Klonisch

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1553058

519 views

Original Research

Published on 05 Sep 2025

Growth hormone reduces retinal inflammation and preserves microglial morphology after optic nerve crush in male rats

in Cellular Neuropathology

Jerusa E. Balderas-Márquez
David Epardo
Lourdes Siqueiros-Márquez
Martha Carranza
Maricela Luna
José Luis Quintanar
Carlos Arámburo
Carlos G. Martínez-Moreno

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1636399

689 views

Review

Accepted on 03 Sep 2025

Spatiotemporal crosstalk among mitochondrial dynamics, NLRP3 1 inflammasome activation, and histone lactylation drives α-synuclein pathology in 2 prodromal Parkinson's disease

in Cellular Neuropathology

Peizhu Lv
Xia Chen
Shiping Liu
Yu Zhang
Yulin Wang
Shun Wang
Yan Bai

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1636185

412 views

Original Research

Published on 03 Sep 2025

Early olfactory dysfunction in experimental autoimmune encephalomyelitis reflects transient brain barrier breach and initiation of neuroinflammation in the olfactory bulb

in Cellular Neuropathology

Andjela Stekic
Milorad Dragic
Ivana Stevanovic
Marina Zaric Kontic
Marija Adzic Bukvic
Sanja Dacic
Milica Ninkovic
Nadezda Nedeljkovic

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1656777

678 views

Review

Published on 02 Sep 2025

Research progress of kinesin family in neurological diseases

in Cellular Neuropathology

Shuyi Liu
Jialing Chen
Liping Shi
Yuan Deng
Zhengbo Wang

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1527305

624 views

Review

Published on 01 Sep 2025

NcRNAs: a potential treatment for spinal cord injury

in Cellular Neuropathology

Jie Bao
Wenhui Zhi
Sheng Qi
Haolong Mo
Ruzhuan Liu
Chunhui Guo

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1645639

527 views

Review

Accepted on 29 Aug 2025

The role of small GTPases in Alzheimer's disease tau pathologies

in Cellular Neuropathology

Peter Hoegy
Yan-Hua Chen
Qun Lu

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1650400

380 views

Original Research

Published on 29 Aug 2025

Engineered miR-214 enriched Schwann cell-derived extracellular vesicles amplify therapeutic efficacy for peripheral neuropathy in T2D mice

in Cellular Neuropathology

Lei Wang
Xuerong Lu
Alexandra Szalad
Yi Zhang
Yanfeng Li
Mei Lu
Amy Kemper
Zhongwu Liu
Xian Shuang Liu
Michael Chopp

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1649830

694 views

Original Research

Accepted on 26 Aug 2025

Sex-specific interneuron vulnerability after traumatic brain injury correlates with neurotrophic signaling and chloride homeostasis, independent of behavioral and network outcomes

in Cellular Neuropathology

Amandine Consumi
Jérôme Laurin
Michael K.E. Schäfer
Christophe Pellegrino
Claudio Rivera

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1572213

329 views

Review

Published on 26 Aug 2025

Human brain organoids: an innovative model for neurological disorder research and therapy

in Cellular Neuropathology

Hancheng Li
Junxiao Zhu
Jieyu Li
Yangkai Wu
Chaohua Luo
Yuting Huang
Jieru Wu
Wenhua Liu
Hongwu Wang
Zhixian Mo

Frontiers in Cellular Neuroscience

doi 10.3389/fncel.2025.1658074

911 views