Frontiers in Dementia | Cellular and Molecular Mechanisms of Dementia

Review

Accepted on 19 May 2025

Evidence that cholinergic mechanisms contribute to hyperexcitability at early stages in Alzheimer's disease

in Cellular and Molecular Mechanisms of Dementia

Helen E Scharfman
Korey Kam
Aine Duffy
John LaFrancois
Paige Leary
Elissavet Chartampila
Stephen D Ginsberg
Christos Panagiots Lisgaras

Frontiers in Dementia

doi 10.3389/frdem.2025.1513144

Original Research

Published on 16 Apr 2025

Neurogenesis drives hippocampal formation-wide spatial transcription alterations in health and Alzheimer's disease

in Cellular and Molecular Mechanisms of Dementia

Zachery D. Morrissey
Pavan Kumar
Trongha X. Phan
Mark Maienschein-Cline
Alex Leow
Orly Lazarov

Frontiers in Dementia

doi 10.3389/frdem.2025.1546433

1,382 views

Original Research

Published on 28 Oct 2024

Quantitative proteomic analysis using a mouse model of Lewy body dementia induced by α-synuclein preformed fibrils injection

in Cellular and Molecular Mechanisms of Dementia

Fatih Akkentli
In kyu Jang
Yoonseop Choi
Young Min
Jinhee Park
Heejin Jo
Leoni Kim
Aashi Mendpara
Bikram Bains
Dongyoon Yoo

Frontiers in Dementia

doi 10.3389/frdem.2024.1477986

1,880 views

Original Research

Published on 17 Jun 2024

Evidence for prodromal changes in neuronal excitability and neuroinflammation in the hippocampus in young alpha-synuclein (A30P) transgenic mice

in Cellular and Molecular Mechanisms of Dementia

Ibtisam Al-Musawi
Bethany H. Dennis
Gavin J. Clowry
Fiona E. N. LeBeau

Frontiers in Dementia

doi 10.3389/frdem.2024.1404841

1,774 views
2 citations

Opinion

Published on 06 Jul 2023

SARS-CoV-2 amyloid, is COVID-19-exacerbated dementia an amyloid disorder in the making?

in Cellular and Molecular Mechanisms of Dementia

Nathaniel G. N. Milton

Frontiers in Dementia

doi 10.3389/frdem.2023.1233340

4,780 views
7 citations

Review

Published on 15 Jun 2023

Hearing loss and its link to cognitive impairment and dementia

in Cellular and Molecular Mechanisms of Dementia

Abdul Azeem
Arun Julleekeea
Beth Knight
Isha Sohail
Michael Bruyns-Haylett
Magdalena Sastre

Frontiers in Dementia

doi 10.3389/frdem.2023.1199319

14,192 views
13 citations

Mini Review

Published on 18 Apr 2023

Accelerated long-term forgetting: A sensitive paradigm for detecting subtle cognitive impairment and evaluating BACE1 inhibitor efficacy in preclinical Alzheimer's disease

in Cellular and Molecular Mechanisms of Dementia

Masuo Ohno

Frontiers in Dementia

doi 10.3389/frdem.2023.1161875

2,087 views
2 citations

Review

Published on 12 Apr 2023

The emerging role of the HTRA1 protease in brain microvascular disease

in Cellular and Molecular Mechanisms of Dementia

Christof Haffner

Frontiers in Dementia

doi 10.3389/frdem.2023.1146055

3,583 views
2 citations

Original Research

Published on 12 Sep 2022

The effect of Aβ seeding is dependent on the presence of knock-in genes in the AppNL−G−F mice

in Cellular and Molecular Mechanisms of Dementia

Sean G. Lacoursiere
Jiri Safar
David Westaway
Majid H. Mohajerani
Robert J. Sutherland

Frontiers in Dementia

doi 10.3389/frdem.2022.941879

2,036 views
2 citations