Frontiers in Dementia | Cellular and Molecular Mechanisms of Dementia

Original Research

Published on 16 Apr 2025

Neurogenesis drives hippocampal formation-wide spatial transcription alterations in health and Alzheimer's disease

in Cellular and Molecular Mechanisms of Dementia

Zachery D. Morrissey
Pavan Kumar
Trongha X. Phan
Mark Maienschein-Cline
Alex Leow
Orly Lazarov

Frontiers in Dementia

doi 10.3389/frdem.2025.1546433

783 views

Original Research

Published on 28 Oct 2024

Quantitative proteomic analysis using a mouse model of Lewy body dementia induced by α-synuclein preformed fibrils injection

in Cellular and Molecular Mechanisms of Dementia

Fatih Akkentli
In kyu Jang
Yoonseop Choi
Young Min
Jinhee Park
Heejin Jo
Leoni Kim
Aashi Mendpara
Bikram Bains
Dongyoon Yoo

Frontiers in Dementia

doi 10.3389/frdem.2024.1477986

1,725 views

Original Research

Published on 17 Jun 2024

Evidence for prodromal changes in neuronal excitability and neuroinflammation in the hippocampus in young alpha-synuclein (A30P) transgenic mice

in Cellular and Molecular Mechanisms of Dementia

Ibtisam Al-Musawi
Bethany H. Dennis
Gavin J. Clowry
Fiona E. N. LeBeau

Frontiers in Dementia

doi 10.3389/frdem.2024.1404841

1,632 views
2 citations

Opinion

Published on 06 Jul 2023

SARS-CoV-2 amyloid, is COVID-19-exacerbated dementia an amyloid disorder in the making?

in Cellular and Molecular Mechanisms of Dementia

Nathaniel G. N. Milton

Frontiers in Dementia

doi 10.3389/frdem.2023.1233340

4,618 views
7 citations

Review

Published on 15 Jun 2023

Hearing loss and its link to cognitive impairment and dementia

in Cellular and Molecular Mechanisms of Dementia

Abdul Azeem
Arun Julleekeea
Beth Knight
Isha Sohail
Michael Bruyns-Haylett
Magdalena Sastre

Frontiers in Dementia

doi 10.3389/frdem.2023.1199319

13,616 views
12 citations

Mini Review

Published on 18 Apr 2023

Accelerated long-term forgetting: A sensitive paradigm for detecting subtle cognitive impairment and evaluating BACE1 inhibitor efficacy in preclinical Alzheimer's disease

in Cellular and Molecular Mechanisms of Dementia

Masuo Ohno

Frontiers in Dementia

doi 10.3389/frdem.2023.1161875

2,031 views
2 citations

Review

Published on 12 Apr 2023

The emerging role of the HTRA1 protease in brain microvascular disease

in Cellular and Molecular Mechanisms of Dementia

Christof Haffner

Frontiers in Dementia

doi 10.3389/frdem.2023.1146055

3,487 views
2 citations

Original Research

Published on 12 Sep 2022

The effect of Aβ seeding is dependent on the presence of knock-in genes in the AppNL−G−F mice

in Cellular and Molecular Mechanisms of Dementia

Sean G. Lacoursiere
Jiri Safar
David Westaway
Majid H. Mohajerani
Robert J. Sutherland

Frontiers in Dementia

doi 10.3389/frdem.2022.941879

1,958 views
2 citations