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REVIEW article

Front. Dent. Med.

Sec. Reconstructive Dentistry

Autogenous Dentin for Socket Preservation: A Narrative Review of Clinical Outcomes Compared to Spontaneous Healing

Provisionally accepted
  • University of Ostrava, Ostrava, Czechia

The final, formatted version of the article will be published soon.

Socket preservation after tooth extraction is a critical procedure to maintain alveolar ridge dimensions for future prosthetic rehabilitation. Autogenous dentin has emerged as a promising graft material due to its biocompatibility, osteoconductivity, and similarity in composition to bone. A systematic search of MEDLINE (PubMed), Scopus, and Web of Science was conducted in January 2025 using a defined MeSH-based strategy. The search was limited to human clinical studies published in the past ten years. Only studies directly comparing groups with autogenous dentin grafts and spontaneous healing without augmentation were included. Six studies met the criteria and were included in the final review, all confirming the safety and biocompatibility of autogenous dentin. Histological evaluations showed active bone formation around dentin particles and high osteoblastic activity without inflammatory response. Cone beam Computed Tomography (CBCT) analysis, performed in most studies, revealed significantly better preservation of ridge dimensions in autogenous dentin matrix (ADM)-augmented sites, especially in the coronal third of the socket. One study highlighted successful outcomes even in periodontally compromised molar extractions. Despite the general agreement among studies, further research (ideally with standardized protocols) is needed, to confirm long-term efficacy in diverse clinical scenarios.

Keywords: autologous dentin, Autogenous dentin, Socket preservation, Ridge augmentation, Spontaneous healing, Tooth Extraction

Received: 28 Sep 2025; Accepted: 31 Oct 2025.

Copyright: © 2025 Jalůvka, Šrubař and Starosta. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Petr Jalůvka, jaluvka.petr@centrum.cz

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.