Frontiers in Drug Discovery

Review

Published on 08 Feb 2024

Machine learning in toxicological sciences: opportunities for assessing drug toxicity

in In silico Methods and Artificial Intelligence for Drug Discovery

Lusine Tonoyan
Arno G. Siraki

Frontiers in Drug Discovery

doi 10.3389/fddsv.2024.1336025

6,720 views
13 citations

Editorial

Published on 07 Feb 2024

Editorial: Discovery of EGFR tyrosine kinase inhibitors for cancer treatment

in Anti-Cancer Drugs

Panupong Mahalapbutr
Thanyada Rungrotmongkol

Frontiers in Drug Discovery

doi 10.3389/fddsv.2024.1365318

1,002 views

Original Research

Published on 05 Feb 2024

Rapid screening of chemicals for their potential to cause specific toxidromes

in In silico Methods and Artificial Intelligence for Drug Discovery

Ruifeng Liu
Mohamed Diwan M. AbdulHameed
Zhen Xu
Benjamin Clancy
Valmik Desai
Anders Wallqvist

Frontiers in Drug Discovery

doi 10.3389/fddsv.2024.1324564

1,416 views

Mini Review

Published on 02 Feb 2024

Deep generative models in the quest for anticancer drugs: ways forward

in In silico Methods and Artificial Intelligence for Drug Discovery

Virgilio Romanelli
Carmen Cerchia
Antonio Lavecchia

Frontiers in Drug Discovery

doi 10.3389/fddsv.2024.1362956

1,726 views
1 citation

Mini Review

Published on 31 Jan 2024

The case of the missing mouse—developing cystic fibrosis drugs without using animals

in Technologies and Strategies to Enable Drug Discovery

Lindsay J. Marshall
Kathleen M. Conlee

Frontiers in Drug Discovery

doi 10.3389/fddsv.2024.1347246

1,795 views

Mini Review

Published on 25 Jan 2024

Identification of first active compounds in drug discovery. how to proceed?

in Technologies and Strategies to Enable Drug Discovery

Stéphane Giraud

Frontiers in Drug Discovery

doi 10.3389/fddsv.2024.1342866

3,523 views
1 citation

Original Research

Published on 18 Dec 2023

Global proteomics insights for a novel small compound targeting the non-integrin Laminin Receptor in a macrophage cell model

in Anti-inflammatory and Immunomodulating Agents

Abigail Haffner
Manoel Figueiredo Neto
C. Samuel Umbaugh
Tiago J. P. Sobreira
Timothy B. Lescun
Herman O. Sintim
Marxa L. Figueiredo

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1326736

1,538 views
2 citations

Review

Published on 15 Dec 2023

Targeting mitochondrial metabolites and nucleic acids as an anti-inflammatory strategy

in Anti-inflammatory and Immunomodulating Agents

Yukun Min
Luke A. J. O’Neill

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1294454

2,036 views
1 citation

Case Report

Published on 11 Dec 2023

Case report: C-reactive protein apheresis in cardiogenic shock: case series from the C-reactive protein apheresis in acute myocardial infarction-registry

in Anti-inflammatory and Immunomodulating Agents

J. Torzewski
S. Mattecka
W. Ries
C. D. Garlichs
F. Heigl
J. Fiedler
A. Sheriff

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1286710

2,416 views
3 citations

Original Research

Published on 11 Dec 2023

Consensus docking aid to model the activity of an inhibitor of DNA methyltransferase 1 inspired by de novo design

in In silico Methods and Artificial Intelligence for Drug Discovery

Diana L. Prado-Romero
Alejandro Gómez-García
Raziel Cedillo-González
Hassan Villegas-Quintero
Juan F. Avellaneda-Tamayo
Edgar López-López
Fernanda I. Saldívar-González
Ana L. Chávez-Hernández
José L. Medina-Franco

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1261094

3,836 views
6 citations

Editorial

Published on 08 Dec 2023

Editorial: Drug discovery for emerging and neglected tropical diseases: advances, challenges and perspectives

in Anti-Infective Agents

Laura Alcântara
Caio Franco
Nilmar Moretti
Denise Pilger

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1346042

1,087 views

Review

Published on 01 Dec 2023

Latest development of approved COVID-19 drugs and COVID-19 drugs undergoing late stage clinical trials

in Anti-Infective Agents

Bingru Feng
Kai Fu

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1304129

2,851 views
3 citations

Mini Review

Published on 30 Nov 2023

Introduction to small molecule drug discovery and preclinical development

in Technologies and Strategies to Enable Drug Discovery

Michelle W. Y. Southey
Michael Brunavs

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1314077

48,434 views
29 citations

Mini Review

Published on 27 Nov 2023

HyBryte™ use in early-stage cutaneous T-cell lymphoma

in Dermatologic Drugs

Brian Poligone
Carolina V. Alexander-Savino
Ellen J. Kim
Aaron R. Mangold
Jennifer Desimone
Henry K. Wong
Adam T. Rumage
Oreola Donini
Andrea Haulenbeek
Christopher J. Schaber

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1298453

2,286 views

Editorial

Published on 23 Nov 2023

Editorial: Advances in anti-malarial drug discovery

in Anti-Infective Agents

Agam Prasad Singh
Brijesh Rathi

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1335842

1,281 views
2 citations

Original Research

Published on 22 Nov 2023

Targeting a cancer-specific LYPD3 glycoform for tumor therapy

in Anti-Cancer Drugs

Theresa Neumann
Evelyn Hartung
Johanna Gellert
Lisa Weiß
Manon Weiske
Naomi Kast
Stephanie Gurka
Sophie Marinoff
Anika Jäkel
Antje Danielczyk

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1298916

3,038 views
1 citation