ORIGINAL RESEARCH article
Front. Gastroenterol.
Sec. The Pancreas
This article is part of the Research TopicOpinions in Biliary and Pancreatic Diseases: 2025View all 3 articles
Management of Late Biliary Complications in Pediatric Liver Transplant Recipients
Provisionally accepted
Davide Cussa1*
Michele Pinon1*
andrea doriguzzi breatta1marco fronda1Pier Luigi Calvo2
Renato Romagnoli1*- 1Dipartimento di Chirurgia Generale e Specialistica, Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino, Turin, Italy
- 2Universita degli Studi di Torino Dipartimento di Scienze della Sanita Pubblica e Pediatriche, Turin, Italy
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Word count: 167 The number of pediatric liver transplant recipients with long-term follow-up exceeding 20 years is steadily increasing. These patients are characterized not only by their extensive medical histories but also by their long future life expectancy. In this context, careful management of post-transplant complications, including biliary issues, is essential.We identified 40 patients from our 193 pediatric transplants performed since the program's inception in 1995, with more than 20 years of follow-up at our center. Thirteen of these patients developed either early or late biliary complications. Five developed complications within the first post-transplant year, while eight developed late complications, which are the main focus of this study. We detail the management of biliary complications in these patients, providing an in-depth analysis of four case models and an overview of the remaining patients.In addition to the standard interventional options, such as percutaneous bilioplasties and surgical revisions of anastomoses, we identified a subgroup that may benefit from a more conservative approach, provided they are closely monitored through a rigorous follow-up protocol
Keywords: biliary com, interventional radiology, liver transplant, Paediatric, Transplant Surgery
Received: 25 Jun 2025; Accepted: 31 Dec 2025.
Copyright: © 2025 Cussa, Pinon, doriguzzi breatta, fronda, Calvo and Romagnoli. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Davide Cussa
Michele Pinon
Renato Romagnoli
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