Frontiers in Genetics

Original Research

Published on 09 Sep 2025

Genetic heterogeneity in childhood leukemia/lymphoma: a Turkish cohort with strong predisposition

in Cancer Genetics and Oncogenomics

Gizem Onder
Ozkan Ozdemir
Fulya Taylan
Cengiz Canpolat
Koray Yalcin
Fatih Erbey
Banu Oflaz Sozmen
Fikret Asarcikli
Turan Bayhan
Yunus Murat Akcabelen

Frontiers in Genetics

doi 10.3389/fgene.2025.1624306

341 views

Original Research

Published on 09 Sep 2025

ZC3H18 regulates alternative splicing and related genes in cervical cancer

in Cancer Genetics and Oncogenomics

Wenjuan Chen
Chenying Liu
Siyi Li
Xingyun Xie
Dan Hu
Yaobin Lin

Frontiers in Genetics

doi 10.3389/fgene.2025.1621238

329 views

Original Research

Published on 09 Sep 2025

Prediction of NR3C1 as a methylation marker for the prevention and treatment of gastric cancer in Rhizoma Atractylodis Macrocephalae based on machine learning algorithm and bioinformatics analysis

in Epigenomics and Epigenetics

Shicong Huang
Qian Gu
Yan Chen
Xiaofang Huang
Yuhua Du
Ziying Zhou
Yi Nan
Ling Yuan

Frontiers in Genetics

doi 10.3389/fgene.2025.1584986

640 views

Review

Accepted on 08 Sep 2025

Beyond single references: pangenome graphs and the future of genomic medicine

in Human and Medical Genomics

Denis M Nyaga
Roan Eltigani Zaied
Olin Silander
Mik Black
Justin Martin O'Sullivan

Frontiers in Genetics

doi 10.3389/fgene.2025.1679660

Data Report

Accepted on 08 Sep 2025

Annotated genome of Aedes japonicus japonicus using a hybrid-assembly approach

in Computational Genomics

Friederike Reuss
Tilman Schell
Haruhiko Isawa
Shinji Kasai
Sven Klimpel
Ruth Müller
Markus Pfenninger
Judith Kochmann

Frontiers in Genetics

doi 10.3389/fgene.2025.1667262

Original Research

Accepted on 08 Sep 2025

A Hypergraph Neural Network for Prioritizing Alzheimer's Disease Risk Genes

in Computational Genomics

Meng Ma
Chao Deng
Yan Liu
Qingqing Cao
Fang Liu
Zhang Yan

Frontiers in Genetics

doi 10.3389/fgene.2025.1668200

Original Research

Accepted on 08 Sep 2025

Genetic and in silico functional characterization of a novel structural variant in the PAH gene by long-read sequencing and structural modelling

in Computational Genomics

Viviana Gallardo
Alexis Gaete
Jonathan Elias Maldonado
Paulina Morales
Angela Peña
Valerie Hamilton
Victor Faundes
Lorena Santa Maria

Frontiers in Genetics

doi 10.3389/fgene.2025.1669007

Original Research

Accepted on 08 Sep 2025

Identification of platelet function-related genes in STEMI patients

in Computational Genomics

Jingjing Zhu
Shuangya Yang
Qing Guo
Yifan Yang
Bei Shi

Frontiers in Genetics

doi 10.3389/fgene.2025.1651794

Original Research

Published on 08 Sep 2025

Constructing a neutrophil extracellular trap model based on machine learning to predict clinical outcomes and immune therapy responses in oral squamous cell carcinoma

in RNA

Jian Wang
Zhenzhen Li
Zhiwei Li
Zijing Yu
Wenpin Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1616868

1,589 views

Original Research

Published on 08 Sep 2025

Comprehensive analysis and validation of angiogenesis in vascular dementia from the perspective of diagnosis, prevention, and treatment

in Human and Medical Genomics

Lijun Xu
Yujiao Wang
Daojun Xie

Frontiers in Genetics

doi 10.3389/fgene.2025.1646991

351 views

Original Research

Published on 08 Sep 2025

A lipid metabolism and lysosome-based risk signature for prognosis and immune response prediction in uterine corpus endometrial carcinoma

in Cancer Genetics and Oncogenomics

Yuanyuan Zhu
Pusheng Yang
Shu Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1594682

344 views

Review

Published on 08 Sep 2025

Mechanisms and recent advances in non-coding RNAs and RNA modifications in antiplatelet drug resistance

in RNA

Ping Ni
Kejie Chen
Jing Xiang
Haifeng Shao
Xiaoling Chen
Qiao Chen
Lingling Wang
Junli Hao
Xinyi Huang
Qing Cao

Frontiers in Genetics

doi 10.3389/fgene.2025.1618105

561 views

Correction

Accepted on 05 Sep 2025

Correction: FEZF1-AS1 drives autophagy-mediated progression of colon cancer and reduced chemosensitivity through inhabiting PI3K/AKT/mTOR signaling pathway

in Cancer Genetics and Oncogenomics

Xiaoping Yang
Zuohui Yuan
Lingzhu Gou
Long Cheng
Zirui Wang
Pingfan Wu
Wang Xiaochun
Xueni Ma
Tiantian Ma
Yi Yu

Frontiers in Genetics

doi 10.3389/fgene.2025.1684479

334 views

Original Research

Published on 05 Sep 2025

Integrative analysis of single-cell and microarray data reveals SPI1-centered macrophage regulatory signatures in ulcerative colitis

in Computational Genomics

Yeqing Yu
Chengwei Yu
Shanshan Dai
Yixu Liu
Lanlan Hu
Weimin Lu

Frontiers in Genetics

doi 10.3389/fgene.2025.1617834

528 views

Original Research

Published on 05 Sep 2025

Geographical distribution of ALDH2 rs671 polymorphism in Chinese angina pectoris patients

in Genetics of Common and Rare Diseases

Wenjia Dong
Junjie Yu
Siqi Xu
Hongsheng Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1543963

569 views

Original Research

Published on 05 Sep 2025

Assembly factor for spindle microtubules (ASPM) promotes osimertinib resistance in lung cancer by increasing EGFR stability

in Cancer Genetics and Oncogenomics

Pengpeng Gui
Zhengyi Han
Zhenyu Yin
Peng Cao
Xin Zhou
Yan Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1593314

869 views