Frontiers in Genetics

Systematic Review

Published on 12 Feb 2026

The impact of circulating tumor DNA on the prognosis of liver cancer and its predictive value: a meta analysis

in Cancer Genetics and Oncogenomics

Bing Wu
Shuhui Ke
Lingling Zhu
Rongrong Dong
Jinqian Luan

Frontiers in Genetics

doi 10.3389/fgene.2026.1767755

391 views

Original Research

Published on 12 Feb 2026

Circ-104792/miR-133a/Bcl-xL influences the proliferation and function of human trophoblastic and decidual stromal cells involved in recurrent abortion disease

in Human and Medical Genomics

Wenjuan Ma
Yuan Ma
Hongli Zhu
Panpan Shi
Xiaochun Huang
Yang Yang

Frontiers in Genetics

doi 10.3389/fgene.2026.1707900

563 views

Original Research

Published on 12 Feb 2026

Genetic polymorphisms of the CDC27 gene are associated with susceptibility and outcomes of non-syndromic congenital heart disease: a bi-ethnic case–control study in Chinese populations

in Genetics of Common and Rare Diseases

Teng Yuan
Feng Zhu
Aikebai Aisan
Tunike Maheshati
Yunxia Li
Ren Tian
You Chen

Frontiers in Genetics

doi 10.3389/fgene.2026.1701812

457 views

Original Research

Accepted on 11 Feb 2026

Age at natural menopause, reproductive lifespan and Alzheimer's Disease in females: is APOE ε4 the missing link?

in Statistical Genetics and Methodology

Francesco Bruno
Patrizia Spadafora
Paolo Abondio
Antonio Qualtieri
Ersilia Paparazzo
Mirella Aurora Aceto
Ida Veltri
Selene De Benedittis
Beatrice Maria Greco
Annamaria Cerantonio

Frontiers in Genetics

125 views

Review

Accepted on 11 Feb 2026

Multiscale Computational Genomics in Wilson Disease: From Atomic Dynamics to Clinical Prediction

in Computational Genomics

Moujun Luan
Qingkai Xue
Yujie Cao
Gangli Cheng
Xingxing Huo

Frontiers in Genetics

Brief Research Report

Published on 11 Feb 2026

Genomic innovation in precision oncology: integrated CRISPR-TTP bioengineering architecture for Ewing Sarcoma (version 4.0 – complete architectural specification)

in Cancer Genetics and Oncogenomics

Alexey Mikhailovich Burlai

Frontiers in Genetics

doi 10.3389/fgene.2026.1727708

838 views

Original Research

Published on 11 Feb 2026

Identification of programmed cell death and mitochondria correlated biomarkers for Kawasaki disease by integrated bioinformatics and machine-learning algorithms with RT-qPCR verification

in Computational Genomics

Tengyang Wang
Chengyi Wang
Yiwei Chen
Xiaofeng Guo

Frontiers in Genetics

doi 10.3389/fgene.2026.1677146

470 views

Original Research

Accepted on 10 Feb 2026

Low-dose X-Ray induced genetic damage in human peripheral blood lymphocytes

in Cytogenomics

Laura Camila Villalba-Rondón
Laura Vélez-Lemus
William Jaramillo-Garzón
Martin Pulido Medellin
Nelson Rangel
Milena Rondón-Lagos

Frontiers in Genetics

224 views

Original Research

Accepted on 10 Feb 2026

Comprehensive analyses of biological function and tumor microenvironment with cuproptosis regulators and construction of a cuproptosis-related scoring system in thyroid cancer based on bioinformatics and experimental validation

in Cancer Genetics and Oncogenomics

Shitong Su
Kun Tian
Zijian Liu
Ruijie Liu

Frontiers in Genetics

Case Report

Published on 10 Feb 2026

Pediatric-onset spinocerebellar ataxia type 3 with dual ATXN3 and HTT gene mutations: a case report and literature-informed hypothesis

in Cytogenomics

Dedong Wang
Mengyao Zhou
Kang Du
Yue Wang
Kunzhi Tang
Yuanfang Duan
Mengting Shi
Haohao Wu

Frontiers in Genetics

doi 10.3389/fgene.2026.1723599

619 views

Methods

Published on 10 Feb 2026

DWGCN: distance-weighted graph convolutional network for robust spatial domain identification in spatial transcriptomics

in Computational Genomics

Chunfang Peng
Guobin Li
Jiamiao Wu
Qiao Fan
Xiaobo Guo

Frontiers in Genetics

doi 10.3389/fgene.2026.1779455

445 views

Original Research

Accepted on 09 Feb 2026

Identification of the PFK Gene Family in Solanum species and 1 Expression Analysis in the Fruitof Solanum lycopersicum 2

in Computational Genomics

Zepeng Wang
Zhongyu Wang
Ruiqiang Xu
Qingyuan Meng
Jintao Wang
Ning Li
Qinghui Yu

Frontiers in Genetics

Mini Review

Accepted on 09 Feb 2026

Emerging Role of Epigenetic Mechanisms in Glaucoma and Their Translational Potential

in RNA

Altaf A Kondkar
Tahira Sultan
Mohammad Azad
Saleh A. Al-Obeidan

Frontiers in Genetics

Correction

Published on 09 Feb 2026

Correction: BAG3-related myofibrillar myopathy: focus on its cardiac involvement

in Genetics of Common and Rare Diseases

Elise Daire
Elena Panaioli
Cyril Gitiaux
Catherine Gardin
Victor Waldmann
Damien Bonnet
Karim Wahbi
Diala Khraiche

Frontiers in Genetics

doi 10.3389/fgene.2026.1786473

461 views

Brief Research Report

Published on 09 Feb 2026

Possible link between the apparently pathogenic FANCI variant and beneficial effects in sports performance

in Applied Genetic Epidemiology

Mariusz Berdyński
Małgorzata Borczyk
Kinga Humińska-Lisowska
Michał Korostyński
Paweł Cięszczyk
Cezary Żekanowski

Frontiers in Genetics

doi 10.3389/fgene.2026.1745694

639 views

Original Research

Published on 09 Feb 2026

Identification and functional analysis of a novel TRAPPC2 intronic variant in a four-generation Chinese pedigree with SEDT

in Genetics of Common and Rare Diseases

Yongfen Lyu
Wuhen Xu
Bin Xu
Xiaojun Tang
Man Xiao
Xiaoping Lan
Yongchen Yang
Xiaozhen Song
Shengnan Wu

Frontiers in Genetics

doi 10.3389/fgene.2026.1763609

451 views

Original Research

Published on 09 Feb 2026

Clinical significance and oncogenic role of ECHDC2 in glioblastoma: a comprehensive analysis based on bioinformatics and in vitro experiments

in Cancer Genetics and Oncogenomics

Shengliang Lin
Tian Wei
Qian Wu
Qingqing Liu
Longyun Hu
Bigui Song
Jiejing Lin
Zewei Zhao
Yi Cai
Xiaoxiao Li

Frontiers in Genetics

doi 10.3389/fgene.2026.1759463

596 views

Correction

Published on 06 Feb 2026

Correction: Transcriptome profiling of intrahepatocytic Plasmodium and their host hepatocytes based on the infection phase and the zonation of the liver

in Epigenomics and Epigenetics

Zhuning Mo
Yuhong Chen
Yujuan Qin
Jian Song

Frontiers in Genetics

doi 10.3389/fgene.2026.1799315

492 views

Original Research

Published on 06 Feb 2026

Identification and functional characterization of a novel pathogenic COL1A1 splicing variant in a Chinese family with osteogenesis imperfecta

in Genetics of Common and Rare Diseases

Hongjuan Nie
Yuanxiong Chen
Peifang Qin
Guiming Xie
Di Zhang
Yifan Sun
Yongjun Mo

Frontiers in Genetics

doi 10.3389/fgene.2026.1758799

867 views

Original Research

Published on 06 Feb 2026

Alterations in gut microbiota and plasma metabolites in pulmonary arterial hypertension secondary to congenital left-to-right shunt heart disease: potential mechanisms and biomarkers

in Human and Medical Genomics

Diwen Li
Tianli Zhao
Xueyang Gong
Yiliya Ahemaiti
Luyao Wei
Yuyang Huang
Shijun Hu

Frontiers in Genetics

doi 10.3389/fgene.2026.1699787

643 views

Editorial

Published on 06 Feb 2026

Editorial: Genetic horizons: exploring genetic biomarkers in therapy and evolution with the aid of artificial intelligence

in Human and Medical Genomics

Yiting Chen
Yiyin Zhang
Georgia Damoraki
Shu Wang

Frontiers in Genetics

doi 10.3389/fgene.2026.1775149

687 views

Original Research

Accepted on 05 Feb 2026

Severity-stratified genetic diagnosis by trio exome sequencing in isolated fetal growth restriction

in Human and Medical Genomics

Ying Li
Weiheng Deng
Minghui Meng
Xiaomin Lu
Mei Guan
Haitang Wei
Xigui Long
Ting Qin

Frontiers in Genetics

120 views

Case Report

Published on 05 Feb 2026

POLR3A-related syndrome complicated with cerebral abscesses: a case report and literature review

in Genetics of Common and Rare Diseases

Mengyao Zhou
Lingli Hou
Huijuan Fan
Yuanfang Duan
Xinye Xie
Haohao Wu
Hanmin Wang
Wei Zhang
Kang Du

Frontiers in Genetics

doi 10.3389/fgene.2026.1668022

765 views

Original Research

Published on 05 Feb 2026

G6PD deficiency as a underrecognized genetic risk factor for rare neurological disorders: evidence from a population-based genetic analysis

in Neurogenomics

Qi Peng
Siping Li
Fen Lv
Xiaomei Zeng
Qingqiu Cheng
Baimao Zhong
Xiaomei Lu

Frontiers in Genetics

doi 10.3389/fgene.2026.1766081

863 views

16,588 articles

articles

The impact of circulating tumor DNA on the prognosis of liver cancer and its predictive value: a meta analysis

Circ-104792/miR-133a/Bcl-xL influences the proliferation and function of human trophoblastic and decidual stromal cells involved in recurrent abortion disease

Genetic polymorphisms of the CDC27 gene are associated with susceptibility and outcomes of non-syndromic congenital heart disease: a bi-ethnic case–control study in Chinese populations

Age at natural menopause, reproductive lifespan and Alzheimer's Disease in females: is APOE ε4 the missing link?

Multiscale Computational Genomics in Wilson Disease: From Atomic Dynamics to Clinical Prediction

Genomic innovation in precision oncology: integrated CRISPR-TTP bioengineering architecture for Ewing Sarcoma (version 4.0 – complete architectural specification)

Identification of programmed cell death and mitochondria correlated biomarkers for Kawasaki disease by integrated bioinformatics and machine-learning algorithms with RT-qPCR verification

Low-dose X-Ray induced genetic damage in human peripheral blood lymphocytes

Comprehensive analyses of biological function and tumor microenvironment with cuproptosis regulators and construction of a cuproptosis-related scoring system in thyroid cancer based on bioinformatics and experimental validation

Pediatric-onset spinocerebellar ataxia type 3 with dual ATXN3 and HTT gene mutations: a case report and literature-informed hypothesis

DWGCN: distance-weighted graph convolutional network for robust spatial domain identification in spatial transcriptomics

Identification of the PFK Gene Family in Solanum species and 1 Expression Analysis in the Fruitof Solanum lycopersicum 2

Emerging Role of Epigenetic Mechanisms in Glaucoma and Their Translational Potential

Correction: BAG3-related myofibrillar myopathy: focus on its cardiac involvement

Possible link between the apparently pathogenic FANCI variant and beneficial effects in sports performance

Identification and functional analysis of a novel TRAPPC2 intronic variant in a four-generation Chinese pedigree with SEDT

Clinical significance and oncogenic role of ECHDC2 in glioblastoma: a comprehensive analysis based on bioinformatics and in vitro experiments

Correction: Transcriptome profiling of intrahepatocytic Plasmodium and their host hepatocytes based on the infection phase and the zonation of the liver

Identification and functional characterization of a novel pathogenic COL1A1 splicing variant in a Chinese family with osteogenesis imperfecta

Alterations in gut microbiota and plasma metabolites in pulmonary arterial hypertension secondary to congenital left-to-right shunt heart disease: potential mechanisms and biomarkers

Editorial: Genetic horizons: exploring genetic biomarkers in therapy and evolution with the aid of artificial intelligence

Severity-stratified genetic diagnosis by trio exome sequencing in isolated fetal growth restriction

POLR3A-related syndrome complicated with cerebral abscesses: a case report and literature review

G6PD deficiency as a underrecognized genetic risk factor for rare neurological disorders: evidence from a population-based genetic analysis