Frontiers in Genetics

Original Research

Published on 14 Apr 2025

Genetic variants in TMPRSS2 influence SARS-CoV-2 infection susceptibility within Mexican Mestizos

in Human and Medical Genomics

Rebeca I. Montero
Cinthia L. Dionicio
Gino Noris
Maricela Piña-Pozas
Carla Santana
Rocío Gómez

Frontiers in Genetics

doi 10.3389/fgene.2025.1558189

2,364 views

Original Research

Published on 14 Apr 2025

Engineering novel features for diabetes complication prediction using synthetic electronic health records

in Computational Genomics

Daniel Voskergian
Burcu Bakir-Gungor
Malik Yousef

Frontiers in Genetics

doi 10.3389/fgene.2025.1451290

2,851 views
2 citations

Original Research

Published on 14 Apr 2025

Explore potential immune-related targets of leeches in the treatment of type 2 diabetes based on network pharmacology and machine learning

in Computational Genomics

Tairan Hu
Zhaohui Fang

Frontiers in Genetics

doi 10.3389/fgene.2025.1554622

3,533 views
2 citations

Case Report

Published on 11 Apr 2025

A novel nonsense mutation in SCAF4 associated with fliedner-zweier syndrome: a case report and review of the literature

in Genetics of Common and Rare Diseases

Zhengfang Chen
Jing Zhao
Xiaoxuan Fan
Xiaoyan Xuan
Xiaoke Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1487352

2,671 views

Editorial

Published on 11 Apr 2025

Editorial: Mendelian randomization: an approach for precision medicine and public health

in Statistical Genetics and Methodology

Xiaoqing Pan

Frontiers in Genetics

doi 10.3389/fgene.2025.1602592

2,796 views
1 citation

Original Research

Published on 11 Apr 2025

Identification of cellular senescence-related genes as biomarkers for lupus nephritis based on bioinformatics

in Genetics of Common and Rare Diseases

Wei Chen
Xiaofang Wang
Guoshun Huang
Qin Sheng
Enchao Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1551450

3,154 views
3 citations

Correction

Published on 11 Apr 2025

Corrigendum: Genetic parameters and genome-wide association for milk production traits and somatic cell score in different lactation stages of Shanghai Holstein population

in Livestock Genomics

Dengying Liu
Zhong Xu
Wei Zhao
Shiyi Wang
Tuowu Li
Kai Zhu
Guanglei Liu
Xiaoduo Zhao
Qishan Wang
Yuchun Pan

Frontiers in Genetics

doi 10.3389/fgene.2025.1604082

1,083 views

Correction

Published on 11 Apr 2025

Corrigendum: Application of rapid clinical exome sequencing technology in the diagnosis of critically ill pediatric patients with suspected genetic diseases

in Genetics of Common and Rare Diseases

Xuejun Ouyang
Dazhi Chi
Yu Zhang
Tian Yu
Qian Zhang
Lei Xu
Victor Wei Zhang
Bin Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1592212

1,352 views

Technology and Code

Published on 10 Apr 2025

Research on the optimization model of anti-breast cancer candidate drugs based on machine learning

in Computational Genomics

Zhou Dong
Hong Chen
Yuchen Yang
Hairong Hao

Frontiers in Genetics

doi 10.3389/fgene.2025.1523015

2,799 views
2 citations

Original Research

Published on 10 Apr 2025

Liver failure diagnosis: key diagnostic biomarkers discovery and bioinformatic validation

in Computational Genomics

Quan Ye
Kai Wang
Hong Ye

Frontiers in Genetics

doi 10.3389/fgene.2025.1554116

2,624 views

Original Research

Published on 10 Apr 2025

Development of genome-wide insertion/deletion markers and genetic diversity in Sipunculus nudus along the Beibu Gulf of China

in Evolutionary and Population Genetics

Yuzhu Ni
Chunli Han
Yating Liu
Manman Li
Weijie He
Jialin Yang
Jie Zou
Huijing Peng
Pengliang Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1542287

1,682 views

Original Research

Published on 09 Apr 2025

Effects of cold environment exposure on female reproductive health and its regulatory mechanisms

in Human and Medical Genomics

Hongyi Sun
Qianqian Zhao
Xiaolan Liang
Yalun He
Yangshuo Li
Jin Yu
Jie Ding
Chaoqin Yu

Frontiers in Genetics

doi 10.3389/fgene.2025.1570053

8,630 views
3 citations

Original Research

Published on 09 Apr 2025

Genetic and clinical profile of high myopia patients with rhegmatogenous retinal detachment

in Genetics of Common and Rare Diseases

Lin Zhou
Farrukhjon Boboev
Hui Chen
Fanwen Jiang
Chun Zhang
Jing Xiao
Hui Jiang
Yongchuan Liao
Zhuping Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1485874

4,126 views
1 citation

Original Research

Published on 09 Apr 2025

A novel end-to-end learning framework for inferring lncRNA-disease associations based on convolution neural network

in Computational Genomics

Shunxian Zhou
Sisi Chen
Jinhai Le
Yangtai Xu
Lei Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1580512

1,792 views
1 citation

Original Research

Published on 09 Apr 2025

Identification of signature genes and relationship with immune cell infiltration in intervertebral disc degeneration

in Genetics of Common and Rare Diseases

Kun Mu
JingChao Geng
Yu Dong
Wei Guo

Frontiers in Genetics

doi 10.3389/fgene.2025.1551124

2,507 views
1 citation

Original Research

Published on 09 Apr 2025

An in vivo systemic massively parallel platform for deciphering animal tissue-specific regulatory function

in Genomic Assay Technology

Ashley R. Brown
Grant A. Fox
Irene M. Kaplow
Alyssa J. Lawler
BaDoi N. Phan
Lahari Gadey
Morgan E. Wirthlin
Easwaran Ramamurthy
Gemma E. May
Ziheng Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1533900

5,387 views
8 citations

Brief Research Report

Published on 09 Apr 2025

Disentangling effects of the DR and DQ isomers encoded by the HLA class II haplotype DRB115:01/DQB106:02 to help establish the true risk allele for FVIII inhibitor development in Hemophilia A

in Immunogenetics

Vincent P. Diego
Bernadette W. Luu
Marcio A. Almeida
Raja Rajalingam
Marco Hofmann
Jacob A. Galan
Eron G. Manusov
Jerry S. Powell
Long V. Dinh
Henry Mead

Frontiers in Genetics

doi 10.3389/fgene.2025.1506862

2,900 views

Original Research

Published on 09 Apr 2025

The classification method of donkey breeds based on SNPs data and machine learning

in Statistical Genetics and Methodology

Dekui Li
Xiaolong Hu
Yongdong Peng

Frontiers in Genetics

doi 10.3389/fgene.2025.1496246

2,225 views
1 citation

Editorial

Published on 08 Apr 2025

Editorial: Recent advancements in RNA-based and targeted therapeutics

in Epigenomics and Epigenetics

Yiming Meng
Viola Bianca Serio
Yuquan Tong
Tao Huang
Elisa Frullanti
Maria Palmieri

Frontiers in Genetics

doi 10.3389/fgene.2025.1603498

2,701 views
2 citations

Original Research

Published on 08 Apr 2025

Development of an alkaliptosis-related lncRNA risk model and immunotherapy target analysis in lung adenocarcinoma

in RNA

Xiang Xiong
Wen Liu
Chuan Yao

Frontiers in Genetics

doi 10.3389/fgene.2025.1573480

2,764 views
2 citations

Original Research

Published on 08 Apr 2025

Comparative analysis of chloroplast genomes in three Araceae species: genomic difference, genetic distance and species morphology association

in Genomics of Plants and Plant-Associated Organisms

Wengang Li
Jingru Liu
Siqin Wang
Ying Ma
Lulu Cui
Yingxian Yao
Ke Sun
Lili Luo

Frontiers in Genetics

doi 10.3389/fgene.2025.1496262

2,446 views
1 citation

Brief Research Report

Published on 07 Apr 2025

Transcriptome profiling of intrahepatocytic Plasmodium and their host hepatocytes based on the infection phase and the zonation of the liver

in Epigenomics and Epigenetics

Zhuning Mo
Yuhong Chen
Yujuan Qin
Jian Song

Frontiers in Genetics

doi 10.3389/fgene.2025.1548487

2,228 views

Original Research

Published on 07 Apr 2025

Immunogenic cell death genes in single-cell and transcriptome analyses perspectives from a prognostic model of cervical cancer

in Cancer Genetics and Oncogenomics

Li Ning
Xiu Li
Yating Xu
Yu Si
Hongting Zhao
Qinling Ren

Frontiers in Genetics

doi 10.3389/fgene.2025.1532523

3,072 views
1 citation

Original Research

Published on 07 Apr 2025

LncRNA H19 promotes adipogenic differentiation disorder by sponging miR-130b-3p to upregulate PPARγ in steroid-induced osteonecrosis of the femoral head

in RNA

Feifei Lin
Min Yi
Shicheng Zhou
Qingyu Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1529797

2,164 views
1 citation

16,549 articles

articles

Genetic variants in TMPRSS2 influence SARS-CoV-2 infection susceptibility within Mexican Mestizos

Engineering novel features for diabetes complication prediction using synthetic electronic health records

Explore potential immune-related targets of leeches in the treatment of type 2 diabetes based on network pharmacology and machine learning

A novel nonsense mutation in SCAF4 associated with fliedner-zweier syndrome: a case report and review of the literature

Editorial: Mendelian randomization: an approach for precision medicine and public health

Identification of cellular senescence-related genes as biomarkers for lupus nephritis based on bioinformatics

Corrigendum: Genetic parameters and genome-wide association for milk production traits and somatic cell score in different lactation stages of Shanghai Holstein population

Corrigendum: Application of rapid clinical exome sequencing technology in the diagnosis of critically ill pediatric patients with suspected genetic diseases

Research on the optimization model of anti-breast cancer candidate drugs based on machine learning

Liver failure diagnosis: key diagnostic biomarkers discovery and bioinformatic validation

Development of genome-wide insertion/deletion markers and genetic diversity in Sipunculus nudus along the Beibu Gulf of China

Effects of cold environment exposure on female reproductive health and its regulatory mechanisms

Genetic and clinical profile of high myopia patients with rhegmatogenous retinal detachment

A novel end-to-end learning framework for inferring lncRNA-disease associations based on convolution neural network

Identification of signature genes and relationship with immune cell infiltration in intervertebral disc degeneration

An in vivo systemic massively parallel platform for deciphering animal tissue-specific regulatory function

Disentangling effects of the DR and DQ isomers encoded by the HLA class II haplotype DRB115:01/DQB106:02 to help establish the true risk allele for FVIII inhibitor development in Hemophilia A

The classification method of donkey breeds based on SNPs data and machine learning

Editorial: Recent advancements in RNA-based and targeted therapeutics

Development of an alkaliptosis-related lncRNA risk model and immunotherapy target analysis in lung adenocarcinoma

Comparative analysis of chloroplast genomes in three Araceae species: genomic difference, genetic distance and species morphology association

Transcriptome profiling of intrahepatocytic Plasmodium and their host hepatocytes based on the infection phase and the zonation of the liver

Immunogenic cell death genes in single-cell and transcriptome analyses perspectives from a prognostic model of cervical cancer

LncRNA H19 promotes adipogenic differentiation disorder by sponging miR-130b-3p to upregulate PPARγ in steroid-induced osteonecrosis of the femoral head

articles

Genetic variants in TMPRSS2 influence SARS-CoV-2 infection susceptibility within Mexican Mestizos

Engineering novel features for diabetes complication prediction using synthetic electronic health records

Explore potential immune-related targets of leeches in the treatment of type 2 diabetes based on network pharmacology and machine learning

A novel nonsense mutation in SCAF4 associated with fliedner-zweier syndrome: a case report and review of the literature

Editorial: Mendelian randomization: an approach for precision medicine and public health

Identification of cellular senescence-related genes as biomarkers for lupus nephritis based on bioinformatics

Corrigendum: Genetic parameters and genome-wide association for milk production traits and somatic cell score in different lactation stages of Shanghai Holstein population

Corrigendum: Application of rapid clinical exome sequencing technology in the diagnosis of critically ill pediatric patients with suspected genetic diseases

Research on the optimization model of anti-breast cancer candidate drugs based on machine learning

Liver failure diagnosis: key diagnostic biomarkers discovery and bioinformatic validation

Development of genome-wide insertion/deletion markers and genetic diversity in Sipunculus nudus along the Beibu Gulf of China

Effects of cold environment exposure on female reproductive health and its regulatory mechanisms

Genetic and clinical profile of high myopia patients with rhegmatogenous retinal detachment

A novel end-to-end learning framework for inferring lncRNA-disease associations based on convolution neural network

Identification of signature genes and relationship with immune cell infiltration in intervertebral disc degeneration

An in vivo systemic massively parallel platform for deciphering animal tissue-specific regulatory function

Disentangling effects of the DR and DQ isomers encoded by the HLA class II haplotype DRB1*15:01/DQB1*06:02 to help establish the true risk allele for FVIII inhibitor development in Hemophilia A

The classification method of donkey breeds based on SNPs data and machine learning

Editorial: Recent advancements in RNA-based and targeted therapeutics

Development of an alkaliptosis-related lncRNA risk model and immunotherapy target analysis in lung adenocarcinoma

Comparative analysis of chloroplast genomes in three Araceae species: genomic difference, genetic distance and species morphology association

Transcriptome profiling of intrahepatocytic Plasmodium and their host hepatocytes based on the infection phase and the zonation of the liver

Immunogenic cell death genes in single-cell and transcriptome analyses perspectives from a prognostic model of cervical cancer

LncRNA H19 promotes adipogenic differentiation disorder by sponging miR-130b-3p to upregulate PPARγ in steroid-induced osteonecrosis of the femoral head

Disentangling effects of the DR and DQ isomers encoded by the HLA class II haplotype DRB115:01/DQB106:02 to help establish the true risk allele for FVIII inhibitor development in Hemophilia A