Frontiers in Genetics | Cancer Genetics and Oncogenomics

Original Research

Published on 14 May 2025

Prognosis of cholangiocarcinoma patients based on multiple patterns of programmed cell death, integrated analysis of the immune microenvironment and drug sensitivity

in Cancer Genetics and Oncogenomics

Yupeng Xu
Jian Sun
Xin Yan
Zhenliao Mao
Yiming Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1457204

1,150 views

Original Research

Published on 09 May 2025

Expression and clinical significance of FANCI gene in pan-cancer: a comprehensive analysis based on multi-omics data

in Cancer Genetics and Oncogenomics

Yunzheng Zhao
Qingyu Li
Jiajun Li
YiFeng Cui
Zhaoyang Lu

Frontiers in Genetics

doi 10.3389/fgene.2025.1542888

1,911 views

Original Research

Published on 02 May 2025

RNA hybrid-capture next-generation sequencing has high sensitivity in identifying known and less characterized oncogenic and likely oncogenic NTRK fusions in a real-world standard-of-care setting

in Cancer Genetics and Oncogenomics

Zachary D. Wallen
Marni Tierno
Erica Schnettler
Alison Roos
Michelle Green
Kobina Amoah
Rebecca A. Previs
Stephanie Hastings
Sarabjot Pabla
Taylor J. Jensen

Frontiers in Genetics

doi 10.3389/fgene.2025.1550706

5,666 views

Review

Published on 01 May 2025

In vitro 3D modeling of colorectal cancer: the pivotal role of the extracellular matrix, stroma and immune modulation

in Cancer Genetics and Oncogenomics

Veroniaina Hanitrarimalala
Zdenka Prgomet
My Hedhammar
Helena Tassidis
Anette Gjörloff Wingren

Frontiers in Genetics

doi 10.3389/fgene.2025.1545017

1,955 views

Original Research

Published on 01 May 2025

Radiomic features and tumor immune microenvironment associated with anaplastic lymphoma kinase-rearranged lung adenocarcinoma and their prognostic value

in Cancer Genetics and Oncogenomics

Ying Han
Wenya Feng
Huaxin Li
Hua Wang
Zhaoxiang Ye

Frontiers in Genetics

doi 10.3389/fgene.2025.1581937

1,398 views

Original Research

Published on 25 Apr 2025

A rare germline mutation reverses the suppressive effect of GPC5 thereby promoting lung adenocarcinoma development and tumorigenesis

in Cancer Genetics and Oncogenomics

Zhifa Zheng
Lina Zhao
Sen Zhao
Zhihong Wu
Nan Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1582504

1,286 views

Original Research

Published on 22 Apr 2025

RNA-seq analysis reveals key genes associated with downregulation of APE1 in esophageal squamous cell carcinoma

in Cancer Genetics and Oncogenomics

Alan Chu
Xiao Liu
Shijia Liu
Mengxi Li
Rui Song
Lanlan Gan
Yongtai Wang
Zongwen Liu
Chen Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1549371

1,035 views

Original Research

Published on 15 Apr 2025

The regulatory role of the circELMOD3-associated ceRNA network in the progression and prognosis of hepatocellular carcinoma

in Cancer Genetics and Oncogenomics

Deyuan Li
Meiliang Liu
Mingshuang Lai
Lijun Wang
Liling Wei
Siqian Wu
Si Liang
Shun Liu
Xiaoyun Zeng

Frontiers in Genetics

doi 10.3389/fgene.2025.1521360

1,353 views

Original Research

Published on 14 Apr 2025

Identification of characteristic genes in cutaneous squamous cell carcinoma based on weighted gene co-expression network analysis

in Cancer Genetics and Oncogenomics

Qipeng Xiao
Pengfei Xu
Wenjun Xu
Qiuhe Song
Yousheng Mao

Frontiers in Genetics

doi 10.3389/fgene.2025.1470584

1,395 views

Original Research

Published on 07 Apr 2025

Immunogenic cell death genes in single-cell and transcriptome analyses perspectives from a prognostic model of cervical cancer

in Cancer Genetics and Oncogenomics

Li Ning
Xiu Li
Yating Xu
Yu Si
Hongting Zhao
Qinling Ren

Frontiers in Genetics

doi 10.3389/fgene.2025.1532523

1,707 views

Original Research

Published on 04 Apr 2025

Biological characteristics and prognosis of acute myeloid leukemia in elderly patients

in Cancer Genetics and Oncogenomics

Zhe Chen
Lina Ding
Jieni Yu
Jing Jin
Zhijian Zhang
Jiaping Fu
Pan Hong
Leihua Fu

Frontiers in Genetics

doi 10.3389/fgene.2025.1524177

1,125 views

Original Research

Published on 04 Apr 2025

The gene signature linked to lactate metabolism predicts the prognosis and correlates with the immune status of head and neck squamous cell carcinoma

in Cancer Genetics and Oncogenomics

Jian Xiao
Wei Li
Guolin Tan
Ru Gao

Frontiers in Genetics

doi 10.3389/fgene.2025.1540841

1,232 views

Original Research

Published on 04 Apr 2025

Transcriptomic signature can distinguish chronic neutrophilic leukemia from ambiguous neutrophilic leukemias

in Cancer Genetics and Oncogenomics

Chao Guo
Zhen-Ling Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1556519

1,193 views

Correction

Published on 03 Apr 2025

Corrigendum: Comprehensive profiling reveals distinct microenvironment and metabolism characterization of lung adenocarcinoma

in Cancer Genetics and Oncogenomics

Chang Li
Chen Tian
Yangyang Liu
Jinyan Liang
Yulan Zeng
Qifan Yang
Yuting Liu
Di Wu
Jingjing Wu
Juanjuan Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1585016

762 views

Original Research

Published on 28 Mar 2025

Integrated promoter-capture Hi-C and Hi-C analysis reveals fine-tuned regulation of the 3D chromatin architecture in colorectal cancer

in Cancer Genetics and Oncogenomics

Ajay Kumar Saw
Ayush Madhok
Anupam Bhattacharya
Soumyadeep Nandi
Sanjeev Galande

Frontiers in Genetics

doi 10.3389/fgene.2025.1553469

2,390 views

Original Research

Published on 26 Mar 2025

Multi-omics pan-cancer analysis reveals the diagnostic and prognostic value of C8orf76, with experimental validation of its impact on lung adenocarcinoma cell proliferation

in Cancer Genetics and Oncogenomics

Xiaohong Zhong
Zhiyong Zhang
Rongjing Gao
Shiqi Ren
Shifang Li
Miao Zhang
Jie Fang
Yanjiao Hou

Frontiers in Genetics

doi 10.3389/fgene.2025.1524422

1,652 views