Frontiers in Genetics | Computational Genomics

Original Research

Accepted on 13 May 2025

Identification of biomarkers for the diagnosis of chronic kidney disease (CKD) with dilated cardiomyopathy (DCM) by bioinformatics analysis and machine learning

in Computational Genomics

Yuhang Liu
Yong Wang
Wenyang Nie
Zhen Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1562891

Original Research

Published on 09 May 2025

Long-read sequencing reveals absence of 5mC in Ogataea parapolymorpha DL-1 genome and introduces telomere-to-telomere assembly

in Computational Genomics

Andrey Eremin
Alexander Sergeev
Arthur Kopylov
Vladimir Rodin
Daniil Malyshev
Tatiana Panova
Igor Polyakov
Maria Zvereva

Frontiers in Genetics

doi 10.3389/fgene.2025.1574332

396 views

Original Research

Accepted on 05 May 2025

Reference-free deconvolution of complex samples based on cross-cell type differential analysis: systematical evaluations with various feature selection options

in Computational Genomics

Weiwei Zhang
Zhonghe Tian
Ling Peng

Frontiers in Genetics

doi 10.3389/fgene.2025.1570781

Methods

Accepted on 05 May 2025

stGuide advances label transfer in spatial transcriptomics through attention-based supervised graph representation learning

in Computational Genomics

Yupeng Xu
Hao Dai
Jinwang Feng
Keren Xu
Qiu Wang
Pingting Gao
Chunman Zuo

Frontiers in Genetics

doi 10.3389/fgene.2025.1566675

Original Research

Accepted on 02 May 2025

From Genetic Data to Kinship Clarity: Employing Machine Learning for Detecting Incestuous Relations

in Computational Genomics

Dejan Jovo Šorgić
Aleksandra Stefanović
Mladen Popović
Dušan Keckarević

Frontiers in Genetics

doi 10.3389/fgene.2025.1578581

Technology and Code

Published on 02 May 2025

TCGADownloadHelper: simplifying TCGA data extraction and preprocessing

in Computational Genomics

Alexandra Anke Baumann
Olaf Wolkenhauer
Markus Wolfien

Frontiers in Genetics

doi 10.3389/fgene.2025.1569290

877 views

Original Research

Accepted on 30 Apr 2025

Integrative transcriptomics and single-cell transcriptomics analysis reveal potential biomarkers and mechanisms of action in papillary thyroid carcinoma

in Computational Genomics

WanChen Cao
Kai Gao
Yi Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1536198

165 views

Opinion

Accepted on 30 Apr 2025

From Bites to Bytes: Understanding How and Why Individual Malaria Risk Varies Using Artificial Intelligence and Causal Inference

in Computational Genomics

Adèle Helena Ribeiro
Julia Pavan Soler
Rodrigo M Corder
Marcelo Ferreira
Dominik Heider

Frontiers in Genetics

doi 10.3389/fgene.2025.1599826

361 views

Original Research

Published on 30 Apr 2025

Impact of nonsynonymous single nucleotide polymorphisms in PROCR gene on protein stability and thrombotic risk: a molecular dynamic approach

in Computational Genomics

Hytham Ahmed Abuagla
Khalid Mohamed Adam
Mohamed E. Elangeeb
Elsadig Mohamed Ahmed
Elshazali W. Ali
Ali M. Edris
Abubakr Ali Elamin MohamedAhmed
Elmoiz Idris Eltieb
Tarig Babikir Algak Khalid
Bahaeldin K. Elamin

Frontiers in Genetics

doi 10.3389/fgene.2025.1580993

494 views

Original Research

Published on 30 Apr 2025

High-precision lung cancer subtype diagnosis on imbalanced exosomal data via Exo-LCClassifier

in Computational Genomics

Siyu Zhan
Hao Yu
Shuang Liu
Ke Qin
Lu Guo

Frontiers in Genetics

doi 10.3389/fgene.2025.1583081

434 views

Original Research

Accepted on 29 Apr 2025

Prediction of Mild Cognitive Impairment Using Blood Multi-Omics Data

in Computational Genomics

Daniel Zhang
Cigdem Sevim Bayrak
Qi Zeng
Minghui Wang
Bin Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1552063

119 views

Original Research

Published on 29 Apr 2025

Constructing ancestral recombination graphs through reinforcement learning

in Computational Genomics

Mélanie Raymond
Marie-Hélène Descary
Cédric Beaulac
Fabrice Larribe

Frontiers in Genetics

doi 10.3389/fgene.2025.1569358

591 views

Original Research

Published on 29 Apr 2025

Potential common mechanisms between primary Sjögren’s syndrome and Hashimoto’s thyroiditis: a public databases-based study

in Computational Genomics

Yanjun Lin
Shupin Tang
Yan Lin
Rihui Wang
Yifeng Xing
Zonghe Xu
Yan Li
Qingxia Fang
Wenwei Wei
Dong Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1520332

496 views

Original Research

Published on 29 Apr 2025

The identification of a blood circular RNA signature that differentiates Chikungunya virus infection

in Computational Genomics

Xue Bai
Hanlin Yan
Guoxia Wen
Shaoxun Yuan
Wanjun Gu

Frontiers in Genetics

doi 10.3389/fgene.2025.1602177

542 views

Original Research

Published on 28 Apr 2025

Single-cell transcriptomic construction of fibroblast score for analysis of immune infiltration in primary and metastatic ovarian cancer

in Computational Genomics

Qian Guo
Hongmei Ding
Qinlin Zheng

Frontiers in Genetics

doi 10.3389/fgene.2025.1549541

486 views

Original Research

Published on 28 Apr 2025

Shared genetic features inference among hypoxia-ischemia diseases in the presence of heterogenous omics data based on a novel risk assessment method

in Computational Genomics

Yifan Zhang
Jianfeng Liu
Zhuoma Basang
Qianxun Yang
Hongce Chen
Shuo Chen
Shaogang Li
Changgui Lei
Mingyan Fang
Huanhuan Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1587854

883 views