Frontiers in Genetics | Computational Genomics

Original Research

Published on 04 Jun 2025

MOLUNGN: a multi-omics graph neural network for biomarker discovery and accurate lung cancer classification

in Computational Genomics

Daifeng Zhang
Guoqiang Bian
Yuanbin Zhang
Jiadong Xie
Chenjun Hu

Frontiers in Genetics

doi 10.3389/fgene.2025.1610284

227 views

Original Research

Accepted on 02 Jun 2025

Integrative bioinformatics analysis and experimental validation reveals key genes and regulatory mechanisms in the development of gout

in Computational Genomics

Ye Yuan
Zhou Jing Guo
Zhiqiang Gao
建鸿陈
Yuejing Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1598835

Original Research

Published on 02 Jun 2025

From genetic data to kinship clarity: employing machine learning for detecting incestuous relations

in Computational Genomics

Dejan Šorgić
Aleksandra Stefanović
Mladen Popović
Dušan Keckarević

Frontiers in Genetics

doi 10.3389/fgene.2025.1578581

385 views

Original Research

Accepted on 30 May 2025

Identification of Neutrophil Extracellular Trap-Related Biomarkers in Ulcerative Colitis Based on Bioinformatics and Machine Learning

in Computational Genomics

Jiao Li
Yupei Liu
Zhiyi Sun
Suqi Zeng
Caisong Zheng

Frontiers in Genetics

doi 10.3389/fgene.2025.1589999

172 views

Original Research

Accepted on 30 May 2025

Insights into the evolution and regulation of miRNAs from the view of their DNA replication temporal domains

in Computational Genomics

Xudong Wu
Tingting Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1544802

114 views

Original Research

Published on 30 May 2025

Integrative transcriptomics and single-cell transcriptomics analyses reveal potential biomarkers and mechanisms of action in papillary thyroid carcinoma

in Computational Genomics

Wanchen Cao
Kai Gao
Yi Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1536198

454 views

Original Research

Published on 30 May 2025

Reference-free deconvolution of complex samples based on cross-cell-type differential analysis: Systematic evaluations with various feature selection options

in Computational Genomics

Weiwei Zhang
Zhonghe Tian
Ling Peng

Frontiers in Genetics

doi 10.3389/fgene.2025.1570781

307 views

Original Research

Published on 30 May 2025

Identification of biomarkers for the diagnosis of chronic kidney disease (CKD) with dilated cardiomyopathy (DCM) by bioinformatics analysis and machine learning

in Computational Genomics

Yuhang Liu
Yong Wang
Wenyang Nie
Zhen Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1562891

540 views

Editorial

Published on 29 May 2025

Editorial: Computational genomic and precision medicine

in Computational Genomics

Zeeshan Ahmed
Ramkumar Thirunavukarasu
Atlas Khan

Frontiers in Genetics

doi 10.3389/fgene.2025.1631668

563 views

Original Research

Accepted on 27 May 2025

Multi-View Contrastive Learning for miRNA-Disease Associations

in Computational Genomics

Wei Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1596018

157 views

Original Research

Accepted on 26 May 2025

Generalized information criteria for personalized gene network inference

in Computational Genomics

Heewon Park
Seiya Imoto
Sadanori Konishi

Frontiers in Genetics

doi 10.3389/fgene.2025.1583756

146 views

Original Research

Published on 26 May 2025

Prediction of mild cognitive impairment using blood multi-omics data

in Computational Genomics

Daniel Frank Zhang
Cigdem Sevim Bayrak
Qi Zeng
Minghui Wang
Bin Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1552063

475 views

Original Research

Accepted on 23 May 2025

Auto-branch multi-task learning for simultaneous prediction of multiple correlated traits associated with Alzheimer's disease

in Computational Genomics

Jiaqi Liang
Zhao Xue
Wenchao Zhou
Guo Xiang-jie
Yalu Wen

Frontiers in Genetics

doi 10.3389/fgene.2025.1538544

181 views

Original Research

Accepted on 23 May 2025

Prediction of lysine crotonylation sites iKcr-DRC: Prediction of lysine crotonylation sites in proteins based on a novel attention module and DenseNet

in Computational Genomics

Xin Wei
Siqin Hu
Jian Tu
Muhammad Akmal Remli

Frontiers in Genetics

doi 10.3389/fgene.2025.1574832

188 views

Methods

Published on 22 May 2025

stGuide advances label transfer in spatial transcriptomics through attention-based supervised graph representation learning

in Computational Genomics

Yupeng Xu
Hao Dai
Jinwang Feng
Keren Xu
Qiu Wang
Pingting Gao
Chunman Zuo

Frontiers in Genetics

doi 10.3389/fgene.2025.1566675

559 views

Opinion

Published on 16 May 2025

From bites to bytes: understanding how and why individual malaria risk varies using artificial intelligence and causal inference

in Computational Genomics

Adèle Helena Ribeiro
Júlia M. P. Soler
Rodrigo M. Corder
Marcelo U. Ferreira
Dominik Heider

Frontiers in Genetics

doi 10.3389/fgene.2025.1599826

950 views