Frontiers in Genetics | Computational Genomics

Original Research

Published on 01 Aug 2025

Research on the diagnosis model of osteoarthritis based on methylation-related genes using machine learning algorithms

in Computational Genomics

Xu Cui
Houlin Ji
Shengyang Guo
Ju Liu
Linyuan Zhang
Yongwei Jia
Yin Cui
Xiaoxiao Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1595676

387 views

Original Research

Published on 31 Jul 2025

Identification of key ferroptosis-related genes and therapeutic target in nasopharyngeal carcinoma

in Computational Genomics

Yuanyuan Gu
Yaozhuang Zhou
Chunhua Xie
Guangyao He
Maosheng Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1595456

364 views

Original Research

Published on 30 Jul 2025

SLC38A1 and STX11 are mitochondria-related biomarkers associated with immune infiltration in osteoarthritis

in Computational Genomics

Wenxue Lv
Mingxiu Yu
Wenhai Yan
Yuli Cai
Weiguo Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1585775

496 views

Original Research

Accepted on 29 Jul 2025

Integrative Machine Learning and Mendelian Randomization Identify Causal Laboratory Biomarkers for Coronary Artery Lesions in Kawasaki Disease: A Prospective Study

in Computational Genomics

Hancao Yang
Meng Wu
Keqing Liang
Yi Li
Ran Yang
Beibei Yuan
Ming Wu
Jin Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1646032

116 views

Original Research

Published on 29 Jul 2025

Commonalities and differences in gene expression patterns in major depressive disorder and chronic spontaneous urticaria: implications for comorbidity

in Computational Genomics

Yibo Jiang
Wen Li
Lihao Zheng
Nan Ba

Frontiers in Genetics

doi 10.3389/fgene.2025.1560832

349 views

Review

Published on 29 Jul 2025

Decoding circRNA translation: challenges and advances in computational method development

in Computational Genomics

Jingjing Zhang
Rui Zhou
Huiling Zhang
Yin Peng
Jintao Meng
Wenhui Xi
Yanjie Wei

Frontiers in Genetics

doi 10.3389/fgene.2025.1654305

278 views

Original Research

Accepted on 25 Jul 2025

The Role of Mitochondria-related Genes and Immune Infiltration in Carotid Atherosclerosis: Identification of Hub Targets through Bioinformatics and Machine Learning Approaches

in Computational Genomics

Dan Liu
Kun Guo
Min Li
Xiaochen Yu
Xue Guan
Xiuru Guan

Frontiers in Genetics

doi 10.3389/fgene.2025.1597445

202 views

Original Research

Published on 24 Jul 2025

A bioinformatics analysis of the correlation between hepatic ischemia–reperfusion injury and postoperative cognitive dysfunction

in Computational Genomics

Qing Hu
Haijie Liu
Yunfei Bao
Zhihao Feng
Hongbo Zhang
Jianling Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1607446

432 views

Original Research

Published on 23 Jul 2025

EPI-DynFusion: enhancer-promoter interaction prediction model based on sequence features and dynamic fusion mechanisms

in Computational Genomics

Ao Zhang
Jianhua Jia
Mingwei Sun
Xin Wei

Frontiers in Genetics

doi 10.3389/fgene.2025.1614222

594 views

Methods

Published on 23 Jul 2025

A likelihood ratio framework for inferring close kinship from dynamically selected SNPs

in Computational Genomics

Jianye Ge
Bruce Budowle
Michael Cariaso
Kristen Mittelman
David Mittelman

Frontiers in Genetics

doi 10.3389/fgene.2025.1635734

743 views

Original Research

Published on 17 Jul 2025

Incorporating graph representation and mutual attention mechanism for MiRNA-MRNA interaction prediction

in Computational Genomics

Tai-Long Shi
Lei Wang
Leon Wong
Zhu-Hong You
Chang-Qing Yu
Chen Jiang
Si-Zhe Liang

Frontiers in Genetics

doi 10.3389/fgene.2025.1637427

720 views

Original Research

Published on 17 Jul 2025

Identification of biomarkers between coronary artery disease and non-alcoholic steatohepatitis: a combination of bioinformatics and machine learning

in Computational Genomics

Yihong Lin
Jingmei Song
Xiaohong Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1573621

832 views

Methods

Published on 15 Jul 2025

Robust consensus nuclear and cell segmentation

in Computational Genomics

Melis O. Irfan
Eduardo A. González-Solares
Tristan Whitmarsh
Alireza Molaeinezhad
Mohammad Al Sa’d
Claire M. Mulvey
Marta Páez Ribes
Atefeh Fatemi
Dario Bressan
Nicholas A. Walton

Frontiers in Genetics

doi 10.3389/fgene.2025.1547788

846 views

Original Research

Accepted on 14 Jul 2025

Analysis and Validation of Novel Biomarkers Related to Palmitoylation in Adenomyosis

in Computational Genomics

Hongyu Zhang
Yufeng Li
Huijuan Cao
Yiling Zhao
Tiansheng Qin
Hongwen Zhu

Frontiers in Genetics

doi 10.3389/fgene.2025.1614573

171 views

Original Research

Published on 14 Jul 2025

Identification and characterization of signature genes related to fetoplacental vascular endothelial cell programming in gestational diabetes mellitus using bioinformatics analysis

in Computational Genomics

Chunhong Liu
Caicheng Wei
Yulan Lu
Fu Chai
Chunfang Wang
Yonglong Zeng
Huatuo Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1600756

852 views

Original Research

Accepted on 09 Jul 2025

Multi-omic Insights into Mitochondrial Dysfunction and Prostatic Disease: Evidence from Transcriptomics, Proteomics, and Methylomics

in Computational Genomics

Binbin Gong
Feixiang Yang
Ning Zhang
Zhengyang Wu
Kun Wang
Kun Wang
Xiangyu Zhang
Yangyang Zhang
Zhengyao Song
Chaozhao Liang

Frontiers in Genetics

doi 10.3389/fgene.2025.1609933

259 views