Frontiers in Genetics | Computational Genomics

Original Research

Published on 22 Aug 2025

Multi-omic insights into mitochondrial dysfunction and prostatic disease: evidence from transcriptomics, proteomics, and methylomics

in Computational Genomics

Binbin Gong
Feixiang Yang
Ning Zhang
Zhengyang Wu
Tianrui Liu
Kun Wang
Xiangyu Zhang
Yangyang Zhang
Zhengyao Song
Chaozhao Liang

Frontiers in Genetics

doi 10.3389/fgene.2025.1609933

472 views

Correction

Published on 21 Aug 2025

Correction: Analysis and validation of novel biomarkers related to palmitoylation in adenomyosis

in Computational Genomics

Hongyu Zhang
Yufeng Li
Huijuan Cao
Yiling Zhao
Hongwen Zhu
Tiansheng Qin

Frontiers in Genetics

doi 10.3389/fgene.2025.1683914

180 views

Correction

Accepted on 19 Aug 2025

Correction: Engineering novel features for diabetes complication prediction using synthetic electronic health records

in Computational Genomics

Daniel Voskergian
Malik Yousef
Burcu Bakir-Gungor

Frontiers in Genetics

doi 10.3389/fgene.2025.1687832

Original Research

Accepted on 15 Aug 2025

Genome-wide Evolution and Function Analysis of ALOG Gene Family in Cotton

in Computational Genomics

Zhen Liu
Jiaying Cao
Zhijuan Cui
Tao Wang
Li Pengtao
Yangyang Wei
Renhai Peng

Frontiers in Genetics

doi 10.3389/fgene.2025.1625634

154 views

Original Research

Published on 15 Aug 2025

Integrative machine learning and Mendelian randomization identify causal laboratory biomarkers for coronary artery lesions in Kawasaki disease: a prospective study

in Computational Genomics

Hancao Yang
Meng Wu
Keqing Liang
Yi Li
Ran Yang
Beibei Yuan
Ming Wu
Jin Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1646032

479 views

Original Research

Accepted on 14 Aug 2025

Multi-omics integration uncovers key transcriptional regulators in triple-negative breast cancer spatial heterogeneity

in Computational Genomics

Ning Zhang
Ye Zhang
Rui-Fei Yang
Hai-Qing Chu
Dong Zhao
Luyu Yang
Yayu Li
Abdur Rehman
XIN ZHOU
Shou-Ping Gong

Frontiers in Genetics

doi 10.3389/fgene.2025.1614254

279 views

Original Research

Accepted on 13 Aug 2025

Integrative Analysis of Single-Cell and Microarray Data Reveals SPI1-Centered Macrophage Regulatory Signatures in Ulcerative Colitis

in Computational Genomics

Yeqing Yu
Chengwei Yu
Shanshan Dai
Yixu Liu
Lanlan Hu
Wei-min Lu

Frontiers in Genetics

doi 10.3389/fgene.2025.1617834

Original Research

Accepted on 11 Aug 2025

Uncovering Differential Gene Expression Between mtRNA-Positive and -Negative Osteosarcoma Cells: Implications Beyond Mitochondrial Function

in Computational Genomics

Xiaoyuan Meng
Zhongcheng Han
Yeerke Wuerkan
Zhigang Wang
Le Ma
Hongbo Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1588581

207 views

Review

Accepted on 11 Aug 2025

Gene-LLMs: A Comprehensive Survey of Transformer-Based Genomic Language Models for Regulatory and Clinical Genomics

in Computational Genomics

Balakrishnan P
Anny Leema
Dhivyashree A Anny Leema
Mohammad Saad
Mohan Babu

Frontiers in Genetics

doi 10.3389/fgene.2025.1634882

273 views

Methods

Published on 08 Aug 2025

BANSMDA: a computational model for predicting potential microbe-disease associations based on bilinear attention networks and sparse autoencoders

in Computational Genomics

Xianzhi Liu
Mingmin Liang
Ge Yu
Shichang Tang
Ouxiang Wu
Bin Zeng
Lei Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1618472

354 views

Original Research

Published on 05 Aug 2025

The role of mitochondria-related genes and immune infiltration in carotid atherosclerosis: identification of hub targets through bioinformatics and machine learning approaches

in Computational Genomics

Dan Liu
Kun Guo
Min Li
Xiaochen Yu
Xue Guan
Xiuru Guan

Frontiers in Genetics

doi 10.3389/fgene.2025.1597445

892 views

Original Research

Accepted on 04 Aug 2025

Dissecting and Validation the Biomarker of Heart Failure Progression in Patients With Atherosclerosis by Single-cell Sequencing, Bioinformatics, and Machine Learning

in Computational Genomics

Liankai Wang
Lihua Ni
Huabo Li
Juan Du
Ke Zhou
Fugui Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1587274

213 views

Original Research

Published on 04 Aug 2025

Analysis and validation of novel biomarkers related to palmitoylation in adenomyosis

in Computational Genomics

Hongyu Zhang
Yufeng Li
Huijuan Cao
Yiling Zhao
Hongwen Zhu
Tiansheng Qin

Frontiers in Genetics

doi 10.3389/fgene.2025.1614573

807 views

Original Research

Published on 01 Aug 2025

Research on the diagnosis model of osteoarthritis based on methylation-related genes using machine learning algorithms

in Computational Genomics

Xu Cui
Houlin Ji
Shengyang Guo
Ju Liu
Linyuan Zhang
Yongwei Jia
Yin Cui
Xiaoxiao Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1595676

810 views

Original Research

Published on 31 Jul 2025

Identification of key ferroptosis-related genes and therapeutic target in nasopharyngeal carcinoma

in Computational Genomics

Yuanyuan Gu
Yaozhuang Zhou
Chunhua Xie
Guangyao He
Maosheng Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1595456

1,014 views

Original Research

Published on 30 Jul 2025

SLC38A1 and STX11 are mitochondria-related biomarkers associated with immune infiltration in osteoarthritis

in Computational Genomics

Wenxue Lv
Mingxiu Yu
Wenhai Yan
Yuli Cai
Weiguo Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1585775

1,126 views