Frontiers in Genetics | Computational Genomics

Original Research

Published on 09 May 2025

Long-read sequencing reveals absence of 5mC in Ogataea parapolymorpha DL-1 genome and introduces telomere-to-telomere assembly

in Computational Genomics

Andrey Eremin
Alexander Sergeev
Arthur Kopylov
Vladimir Rodin
Daniil Malyshev
Tatiana Panova
Igor Polyakov
Maria Zvereva

Frontiers in Genetics

doi 10.3389/fgene.2025.1574332

208 views

Technology and Code

Published on 02 May 2025

TCGADownloadHelper: simplifying TCGA data extraction and preprocessing

in Computational Genomics

Alexandra Anke Baumann
Olaf Wolkenhauer
Markus Wolfien

Frontiers in Genetics

doi 10.3389/fgene.2025.1569290

732 views

Original Research

Accepted on 30 Apr 2025

Integrative transcriptomics and single-cell transcriptomics analysis reveal potential biomarkers and mechanisms of action in papillary thyroid carcinoma

in Computational Genomics

WanChen Cao
Kai Gao
Yi Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1536198

139 views

Opinion

Accepted on 30 Apr 2025

From Bites to Bytes: Understanding How and Why Individual Malaria Risk Varies Using Artificial Intelligence and Causal Inference

in Computational Genomics

Adèle Helena Ribeiro
Julia Pavan Soler
Rodrigo M Corder
Marcelo Ferreira
Dominik Heider

Frontiers in Genetics

doi 10.3389/fgene.2025.1599826

286 views

Original Research

Published on 30 Apr 2025

Impact of nonsynonymous single nucleotide polymorphisms in PROCR gene on protein stability and thrombotic risk: a molecular dynamic approach

in Computational Genomics

Hytham Ahmed Abuagla
Khalid Mohamed Adam
Mohamed E. Elangeeb
Elsadig Mohamed Ahmed
Elshazali W. Ali
Ali M. Edris
Abubakr Ali Elamin MohamedAhmed
Elmoiz Idris Eltieb
Tarig Babikir Algak Khalid
Bahaeldin K. Elamin

Frontiers in Genetics

doi 10.3389/fgene.2025.1580993

438 views

Original Research

Published on 30 Apr 2025

High-precision lung cancer subtype diagnosis on imbalanced exosomal data via Exo-LCClassifier

in Computational Genomics

Siyu Zhan
Hao Yu
Shuang Liu
Ke Qin
Lu Guo

Frontiers in Genetics

doi 10.3389/fgene.2025.1583081

377 views

Original Research

Accepted on 29 Apr 2025

Prediction of Mild Cognitive Impairment Using Blood Multi-Omics Data

in Computational Genomics

Daniel Zhang
Cigdem Sevim Bayrak
Qi Zeng
Minghui Wang
Bin Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1552063

Original Research

Published on 29 Apr 2025

Constructing ancestral recombination graphs through reinforcement learning

in Computational Genomics

Mélanie Raymond
Marie-Hélène Descary
Cédric Beaulac
Fabrice Larribe

Frontiers in Genetics

doi 10.3389/fgene.2025.1569358

487 views

Original Research

Published on 29 Apr 2025

Potential common mechanisms between primary Sjögren’s syndrome and Hashimoto’s thyroiditis: a public databases-based study

in Computational Genomics

Yanjun Lin
Shupin Tang
Yan Lin
Rihui Wang
Yifeng Xing
Zonghe Xu
Yan Li
Qingxia Fang
Wenwei Wei
Dong Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1520332

417 views

Original Research

Published on 29 Apr 2025

The identification of a blood circular RNA signature that differentiates Chikungunya virus infection

in Computational Genomics

Xue Bai
Hanlin Yan
Guoxia Wen
Shaoxun Yuan
Wanjun Gu

Frontiers in Genetics

doi 10.3389/fgene.2025.1602177

477 views

Original Research

Published on 28 Apr 2025

Single-cell transcriptomic construction of fibroblast score for analysis of immune infiltration in primary and metastatic ovarian cancer

in Computational Genomics

Qian Guo
Hongmei Ding
Qinlin Zheng

Frontiers in Genetics

doi 10.3389/fgene.2025.1549541

331 views

Original Research

Published on 28 Apr 2025

Shared genetic features inference among hypoxia-ischemia diseases in the presence of heterogenous omics data based on a novel risk assessment method

in Computational Genomics

Yifan Zhang
Jianfeng Liu
Zhuoma Basang
Qianxun Yang
Hongce Chen
Shuo Chen
Shaogang Li
Changgui Lei
Mingyan Fang
Huanhuan Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1587854

631 views

Original Research

Published on 28 Apr 2025

Exploring WNT pathway dysregulation in serrated colorectal cancer for improved diagnostic and therapeutic strategies

in Computational Genomics

Fengzhi Zhu
Helen Hoi Ning Yan
Yin Tong
Yueliang Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1586867

382 views

Original Research

Published on 24 Apr 2025

Key gene screening and diagnostic model establishment for acute type a aortic dissection

in Computational Genomics

Yue Pan
Zhiming Yu
Xiaoyu Qian
Xuesong Zhang
Qun Xue
Weizhang Xiao

Frontiers in Genetics

doi 10.3389/fgene.2025.1586880

434 views

Original Research

Published on 24 Apr 2025

Integration of bulk RNA-seq and scRNA-seq reveals transcriptomic signatures associated with deep vein thrombosis

in Computational Genomics

Bao-ze Pan
Ming-jun Jiang
Li-ming Deng
Jie Chen
Xian-peng Dai
Zi-xuan Wu
Zhi-he Deng
Dong-yang Luo
Yang-yi-jing Wang
Dan Ning

Frontiers in Genetics

doi 10.3389/fgene.2025.1551879

468 views

Methods

Published on 24 Apr 2025

MSI expresso: a software for determining MSI status and detecting MSI-related transcription events from RNA sequencing data

in Computational Genomics

Emmanuel Tubacher
Alexandre How-Kit
Mourad Sahbatou
Alex Duval
Victor Renault
Jean-François Deleuze

Frontiers in Genetics

doi 10.3389/fgene.2025.1523278

467 views