Frontiers in Genetics | Computational Genomics

Original Research

Published on 25 Jun 2025

A machine learning framework for predicting cognitive impairment in aging populations using urinary metal and demographic data

in Computational Genomics

Fengchun Ren
Xiao Zhao
Qin Yang
Huaqiang Liao
Yudong Zhang
Xuemei Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1631228

192 views

Methods

Accepted on 24 Jun 2025

Robust Consensus Nuclear and Cell Segmentation

in Computational Genomics

Melis Omer Irfan
Eduardo A Gonz Ález-Solares
Tristan Whitmarsh
Alireza Molaeinezhad
Mohammad Al Sa'd
Claire M Mulvey
Marta P Áez Ribes
Dario Bressan
Nicholas A Walton

Frontiers in Genetics

doi 10.3389/fgene.2025.1547788

Original Research

Accepted on 24 Jun 2025

A bioinformatics analysis on the correlation between hepatic ischemiareperfusion injury and postoperative cognitive dysfunction

in Computational Genomics

Qing Hu
Haijie Liu
Yunfei Bao
Zhihao Feng
Hongbo Zhang
Jianling Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1607446

Methods

Accepted on 24 Jun 2025

A Likelihood Ratio Framework for Inferring Close Kinship from Dynamically Selected SNPs

in Computational Genomics

Jianye Ge
Bruce Budowle
Michael Cariaso
Kristen Mittelman
David Mittelman

Frontiers in Genetics

doi 10.3389/fgene.2025.1635734

Original Research

Published on 24 Jun 2025

An analysis of gene expression profiles through machine learning uncovers the new diagnostic signature for diabetic foot ulcers

in Computational Genomics

Yingnan Li
Ning Xiao
Zhuoqun Wang
Wenhai Wang
Fengjiao Li
Jiren Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1620749

431 views

Original Research

Published on 23 Jun 2025

CYLD as a key regulator of myocardial infarction-to-heart failure transition revealed by multi-omics integration

in Computational Genomics

Jingya Xu
Zhonghua Dong
Zhaodong Li
Xuan Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1592985

348 views

Original Research

Published on 23 Jun 2025

Insights into the evolution and regulation of miRNAs from the view of their DNA replication temporal domains

in Computational Genomics

Xudong Wu
Tingting Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1544802

345 views

Original Research

Published on 20 Jun 2025

Generalized information criteria for personalized gene network inference

in Computational Genomics

Heewon Park
Seiya Imoto
Sadanori Konishi

Frontiers in Genetics

doi 10.3389/fgene.2025.1583756

418 views

Original Research

Published on 20 Jun 2025

Integrative bioinformatics analysis of pyroptosis-related genes and immune infiltration patterns in childhood asthma

in Computational Genomics

Di Lian
Chenye Lin
Meiling Xie
JianXing Wei
Xueling Huang
Ke Lian
Qiuyu Tang

Frontiers in Genetics

doi 10.3389/fgene.2025.1557709

395 views

Original Research

Published on 20 Jun 2025

Identification of neutrophil extracellular trap-related biomarkers in ulcerative colitis based on bioinformatics and machine learning

in Computational Genomics

Jiao Li
Yupei Liu
Zhiyi Sun
Suqi Zeng
Caisong Zheng

Frontiers in Genetics

doi 10.3389/fgene.2025.1589999

446 views

Original Research

Accepted on 19 Jun 2025

Identification and Characterization of Signature Genes Related to Fetoplacental Vascular Endothelial Cell Programming in Gestational Diabetes Mellitus Using Bioinformatics Analysis

in Computational Genomics

Chunhong Liu
Caicheng Wei
Yulan Lu
Fu Chai
Chunfang Wang
Yonglong Zeng
Huatuo Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1600756

111 views

Original Research

Accepted on 19 Jun 2025

HyenaCircle: a HyenaDNA-based pretrained large language model for long eccDNA prediction

in Computational Genomics

Fuyu Li
Wenxiang Lu
Yunfei Bai

Frontiers in Genetics

doi 10.3389/fgene.2025.1641162

135 views

Original Research

Published on 19 Jun 2025

Identification of biomarkers associated with mitochondrial dysfunction and programmed cell death in chronic obstructive pulmonary disease via transcriptomics

in Computational Genomics

Xiaojuan Yang
Yutao Duan
Lei Qiu
Xia Huang
Fei Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1567173

452 views

Original Research

Published on 18 Jun 2025

Integrative bioinformatics analysis and experimental validation reveals key genes and regulatory mechanisms in the development of gout

in Computational Genomics

Ye Yuan
Zhiqiang Gao
Jianhong Chen
Yuejing Liu
Jingguo Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1598835

365 views

Original Research

Accepted on 16 Jun 2025

Geometry-Enhanced Graph Neural Networks Accelerate circRNA Therapeutic Target Discovery

in Computational Genomics

Zhen Li
Mingming Qi
Juyuan Huang
Wei Zhang
Xu Tan
Yifan Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1633391

131 views

Original Research

Accepted on 16 Jun 2025

Exploration of biomarkers associated with histone lactylation modification in spinal cord injury

in Computational Genomics

Yi Song Sun
Gao Jie
Jing Jue Hua

Frontiers in Genetics

doi 10.3389/fgene.2025.1609439

100 views