Frontiers in Genetics | Computational Genomics

Original Research

Published on 11 Nov 2022

A novel immune signature predicts immunotherapy responsiveness and reveals the landscape of the tumor immune microenvironment in head and neck squamous cell carcinoma

in Computational Genomics

Qiwei Wang
Yinan Zhao
Fang Wang
Guolin Tan

Frontiers in Genetics

doi 10.3389/fgene.2022.1051051

3,063 views
5 citations

Perspective

Published on 10 Nov 2022

From the reference human genome to human pangenome: Premise, promise and challenge

in Computational Genomics

Vipin Singh
Shweta Pandey
Anshu Bhardwaj

Frontiers in Genetics

doi 10.3389/fgene.2022.1042550

7,019 views
14 citations

Original Research

Published on 09 Nov 2022

Identification of COVID-19 severity biomarkers based on feature selection on single-cell RNA-Seq data of CD8+ T cells

in Computational Genomics

Jian Lu
Mei Meng
XianChao Zhou
Shijian Ding
KaiYan Feng
Zhenbing Zeng
Tao Huang
Yu-Dong Cai

Frontiers in Genetics

doi 10.3389/fgene.2022.1053772

3,746 views
8 citations

Brief Research Report

Published on 09 Nov 2022

Transcriptomic analysis of isolated and pooled human postmortem cerebellar Purkinje cells in autism spectrum disorders

in Computational Genomics

Cheryl Brandenburg
Anthony J. Griswold
Derek J. Van Booven
Michaela B. C. Kilander
Jeannine A. Frei
Michael W. Nestor
Derek M. Dykxhoorn
Margaret A. Pericak-Vance
Gene J. Blatt

Frontiers in Genetics

doi 10.3389/fgene.2022.944837

3,675 views
7 citations

Original Research

Published on 07 Nov 2022

Identification of biomarkers in nonalcoholic fatty liver disease: A machine learning method and experimental study

in Computational Genomics

Na Han
Juan He
Lixin Shi
Miao Zhang
Jing Zheng
Yuanshuo Fan

Frontiers in Genetics

doi 10.3389/fgene.2022.1020899

6,516 views
16 citations

Original Research

Published on 07 Nov 2022

Integrated bioinformatics, network pharmacology, and artificial intelligence to predict the mechanism of celastrol against muscle atrophy caused by colorectal cancer

in Computational Genomics

Ming Wu
Yan Zhang

Frontiers in Genetics

doi 10.3389/fgene.2022.1012932

3,346 views
5 citations

Original Research

Published on 04 Nov 2022

A comparative analysis of telomere length maintenance circuits in fission and budding yeast

in Computational Genomics

Iftah Peretz
Martin Kupiec
Roded Sharan

Frontiers in Genetics

doi 10.3389/fgene.2022.1033113

2,250 views

Original Research

Published on 04 Nov 2022

Adverse effect signature extraction and prediction for drugs treating COVID-19

in Computational Genomics

Han Wang
Xin Wang
Teng Li
Daoyuan Lai
Yan Dora Zhang

Frontiers in Genetics

doi 10.3389/fgene.2022.1019940

2,608 views
1 citation

Original Research

Published on 03 Nov 2022

Mechanisms underlying the therapeutic effects of 4-octyl itaconate in treating sepsis based on network pharmacology and molecular docking

in Computational Genomics

Maolin Chen
Wenxing Su
Fangling Chen
Tianlun Lai
Yilun Liu
Daojiang Yu

Frontiers in Genetics

doi 10.3389/fgene.2022.1056405

4,059 views
4 citations

Original Research

Published on 03 Nov 2022

MiRNA-190a-5p promotes primordial follicle hyperactivation by targeting PHLPP1 in premature ovarian failure

in Computational Genomics

Yuchi Zhang
Dongwei Han
Xiaoyan Yu
Xinyu Shao
Chuju Zong
Manyu Zhang
Junzhi Wang
Jingwen Liang
Pengling Ge

Frontiers in Genetics

doi 10.3389/fgene.2022.1034832

2,831 views
6 citations

Original Research

Published on 03 Nov 2022

LABAMPsGCN: A framework for identifying lactic acid bacteria antimicrobial peptides based on graph convolutional neural network

in Computational Genomics

Tong-Jie Sun
He-Long Bu
Xin Yan
Zhi-Hong Sun
Mu-Su Zha
Gai-Fang Dong

Frontiers in Genetics

doi 10.3389/fgene.2022.1062576

2,782 views
11 citations

Original Research

Published on 03 Nov 2022

Phylogenomics as an effective approach to untangle cross-species hybridization event: A case study in the family Nymphaeaceae

in Computational Genomics

Lin Cheng
Qunwei Han
Fei Chen
Mengge Li
Tiago Santana Balbuena
Yiyong Zhao

Frontiers in Genetics

doi 10.3389/fgene.2022.1031705

2,351 views
4 citations

Original Research

Published on 01 Nov 2022

Influence of single-cell RNA sequencing data integration on the performance of differential gene expression analysis

in Computational Genomics

Tomasz Kujawa
Michał Marczyk
Joanna Polanska

Frontiers in Genetics

doi 10.3389/fgene.2022.1009316

5,588 views
4 citations

Data Report

Published on 01 Nov 2022

Rounding up the annual ryegrass genome: High-quality reference genome of Lolium rigidum

in Computational Genomics

Jefferson Paril
Gunjan Pandey
Emma M. Barnett
Rahul V. Rane
Leon Court
Thomas Walsh
Alexandre Fournier-Level

Frontiers in Genetics

doi 10.3389/fgene.2022.1012694

4,520 views
13 citations

Original Research

Published on 01 Nov 2022

Novel peripheral blood diagnostic biomarkers screened by machine learning algorithms in ankylosing spondylitis

in Computational Genomics

Jian Wen
Lijia Wan
Xieping Dong

Frontiers in Genetics

doi 10.3389/fgene.2022.1032010

2,346 views
7 citations

Original Research

Published on 31 Oct 2022

Prognostic value of nutritional and inflammatory indicators in females with esophageal squamous cell cancer: A propensity score matching study

in Computational Genomics

Yuping Li
Huaichao Luo
Bo Ye
Kaijiong Zhang
Chang Liu
Ruiling Zu
Sujiao Ni
Qiao He
Lubei Rao
Qifeng Wang

Frontiers in Genetics

doi 10.3389/fgene.2022.1026685

1,450 views
2 citations