Frontiers in Genetics

Original Research

Published on 19 Feb 2026

Clinical and genetic features of hereditary transthyretin amyloidosis with polyneuropathy in China: insights from case analysis and literature review

Xiaoyang Yuan
Yajun Lv
Xue Wang
Bing Han
Bingchuan Xie

Frontiers in Genetics

doi 10.3389/fgene.2026.1715134

120 views

Brief Research Report

Accepted on 18 Feb 2026

Fragmenting the Future with FLARE: A Comprehensive Fragmentomics Pipeline Based on Long-read Nanopore Sequencing

Marica Ficorilli
Marta Lucchetta
Deborah Lenoci
Ilenia Rolli
Nicole Farina
Valentina Cristofaro
Lorenzo Giannini
Arianna Ottini
Alberto Deganello
Stefano Cavalieri

Frontiers in Genetics

Original Research

Accepted on 18 Feb 2026

CFTR Gene Variant Detection in Moroccan Individuals via Nanopore Long-Read Sequencing

Nada EL Makhzen
Alexander Nater
Jean-Sébastien Rougier
Alexandre Bokhobza
Javier Sanz
Christiane Zweier
Anne-Flore Hämmerli
Rémy Bruggmann
Laila Bouguenouch
Mounia Lakhdar Idrissi

Frontiers in Genetics

Editorial

Accepted on 18 Feb 2026

Editorial: Insights in human and medical genomics 2024

Jared C Roach
Maxim B Freidin

Frontiers in Genetics

Brief Research Report

Accepted on 18 Feb 2026

Functional validation of the novel KIF5A p.R17Q VUS reveals defective axonal transport in iPSC-motoneurons from a SPG10 patient

Serena Santangelo
Valeria Casiraghi
Claudia Fallini
Sabrina Invernizzi
Silvia Peverelli
Martina Bertocchi
Monica Feole
Marta Cozzi
Stefania Magri
Angelo Poletti

Frontiers in Genetics

Original Research

Accepted on 18 Feb 2026

Navigating Tensions between Scientific Advancement and Ethical Practice in Biobanking: A Qualitative Study in Japan

Masanori Oikawa
Yoshiyuki Takimoto

Frontiers in Genetics

Original Research

Accepted on 18 Feb 2026

Promoter hypomethylation of CDH7: a novel epigenetic marker associated with cerebral small vessel disease

Jeeyeon Kim
Jihye Park
Keunsoo Kang
Young Ho Lee
Byoung-Soo Shin
Dae-Hyun Kim
Dong‑Ick Shin
Seong Hwan Ahn
Jae Guk Kim
Hyun Goo Kang

Frontiers in Genetics

Original Research

Published on 18 Feb 2026

Geneticization outside genetics’ birthplace: ethical, legal and social implications in the Gulf Cooperation Council region

Safa Shaheen
Mohammed Ghaly

Frontiers in Genetics

doi 10.3389/fgene.2026.1716793

180 views

Original Research

Published on 18 Feb 2026

A SCN1A missense variant (c.4522T>A, p.(Tyr1508Asn) associated with genetic epilepsy with febrile seizures plus: clinical phenotype and genetic analysis of a Chinese pedigree

Xiao-Ling Li

Frontiers in Genetics

doi 10.3389/fgene.2026.1746234

123 views

Editorial

Published on 18 Feb 2026

Editorial: Advancements in sequencing technologies for epigenomic and transcriptomic analysis: from bulk to single-cell resolution

Laura Veschetti
Massimiliano Cocca
Dougba Noel Dago
Giovanni Malerba

Frontiers in Genetics

doi 10.3389/fgene.2026.1807544

101 views

Original Research

Published on 18 Feb 2026

Novel LARS2 variants in patients with Perrault syndrome: expanding the genetic spectrum and phenotypic heterogeneity

Zibin Lin
Jiale Xiang
Xiangzhong Sun
Xinyu Shi
Xiaozhou Liu
Qinming Cai
Jing Yang
Nana Song
Haodong Ye
Jiangfan Xu

Frontiers in Genetics

doi 10.3389/fgene.2026.1785502

265 views

Case Report

Published on 18 Feb 2026

Case Report: Identification of a de novo missense variant in the N-terminal zinc-finger domain of ZEB2 in a patient presenting with neurodevelopmental delay and recurrent pulmonary infections

Jing Chen
Xiaodong Jiang
Wei Su
Jingjing Li
Shuang Chen
Ke Xu
Juxian Teng
Weihong Zhang
Hongmin Zhu

Frontiers in Genetics

doi 10.3389/fgene.2026.1778727

159 views

Original Research

Published on 18 Feb 2026

Plastic film mulching enhances flavonoid accumulation in the roots of Scutellaria baicalensis

Bin Ma
Ying Niu
Yang-Mei Bao
Hua Liu
Dongqing Wang
Wenjin Zhang
Ming Li
Lan-Ping Guo

Frontiers in Genetics

doi 10.3389/fgene.2026.1739808

176 views

Original Research

Accepted on 17 Feb 2026

Identification of gene expression signatures associated with neuroinflammation in discogenic sciatica using machine learning and experimental validation

Fei Jiang
Yang Xu
Xi-Hong Ye
Bin Zheng
Guang-Lei Zhang
Ren-Hu Li

Frontiers in Genetics

Original Research

Published on 17 Feb 2026

Whole-genome sequencing reveals genomic diversity and selection signatures for adaptation in South African Afrikaner and Bonsmara cattle

D. Alberts
E. van Marle-Köster
F. Joubert
D. P. Berry

Frontiers in Genetics

doi 10.3389/fgene.2026.1717538

501 views

Case Report

Published on 17 Feb 2026

Case Report: Expanding the diagnostic spectrum of non-invasive prenatal testing to structural chromosomal abnormalities

Jong Chul Kim
Hyunjin Kim
HeeYeon Jang
Minyeon Go
Ji Eun Park
Chang Soo Ryu
Mi Uk Chin
Eun Hye Kim
Young Jin Lee
Sung Han Shim

Frontiers in Genetics

doi 10.3389/fgene.2026.1746287

503 views

Original Research

Accepted on 16 Feb 2026

BHLHE41–SLC7A11 transcriptional axis and chromatin remodeling signatures in osteogenic-lineage disulfidptosis-like stress in osteoporosis

Xiaoming Zhao
Wenya Xue
Ju Ga
Yilei Zhang
Jinghong Chen
Yingang Zhang

Frontiers in Genetics

Original Research

Accepted on 16 Feb 2026

GViT-GP: Injecting the Genomic Relationship Matrix as an Inductive Bias into a Vision Transformer via Cross-Attention for Genomic Prediction

Jingxuan Li
Wei Luo
Honghao Yu
Xishi Huang
Jisi Ma
Shijun Li
Yong Li
Lantao Gu

Frontiers in Genetics

Original Research

Accepted on 16 Feb 2026

Potential effects on the signaling network mediated by overexpression of the vitronectin gene in Hu sheep ruminal epithelial cells using multi-omics analysis

Bingqian Zhong
LuYu Ma
Hua Ni
Eli Subinur
AiWen Zhu
Wei Yan
YuTao Wang

Frontiers in Genetics

Original Research

Published on 16 Feb 2026

Glycolysis-related gene signatures in spinal cord injury pathophysiology identification through integrative gene expression analysis

Xiaoqin Liu
Zhuang Wang
Jiating Hu
Guodong Shi
Xin Ai

Frontiers in Genetics

doi 10.3389/fgene.2026.1759563

536 views

Editorial

Published on 16 Feb 2026

Editorial: Integrating genetics and proteomics for drug discovery

Karunakaran Kalesh
Liang Xue

Frontiers in Genetics

doi 10.3389/fgene.2026.1806492

351 views

Correction

Published on 16 Feb 2026

Correction: Population genetics of Plasmodium vivax with transmission decline and rebound in two endemic areas of Papua New Guinea

Abebe A. Fola
Somya Mehra
Zahra Razook
Dulcie Lautu-Gumal
Elma Nate
Stuart Lee
Johanna Helena Kattenberg
Cristian Koepfli
James Kazura
Maria Ome-Kaius

Frontiers in Genetics

doi 10.3389/fgene.2026.1805349

153 views

Editorial

Published on 16 Feb 2026

Editorial: Insights in applied genetic epidemiology 2025

Hui-Qi Qu
M. Geoffrey Hayes

Frontiers in Genetics

doi 10.3389/fgene.2026.1801003

469 views

Original Research

Published on 16 Feb 2026

Differentially expressed proteins in plasma-derived extracellular vesicles from chronic myeloid leukemia patients

Denise Kusma Wosniaki
Alexandre Luiz Korte de Azevedo
Anelis Maria Marin
Alexis Germán Murillo Carrasco
Luciana Nogueira de Sousa Andrade
Rodrigo Brant
Michel Batista
Talita Helen Bombardelli Gomig
Roger Chammas
Mateus Nóbrega Aoki

Frontiers in Genetics

doi 10.3389/fgene.2026.1762244

424 views

16,584 Publications

volumes

Volume 17 - 2026

Clinical and genetic features of hereditary transthyretin amyloidosis with polyneuropathy in China: insights from case analysis and literature review

Fragmenting the Future with FLARE: A Comprehensive Fragmentomics Pipeline Based on Long-read Nanopore Sequencing

CFTR Gene Variant Detection in Moroccan Individuals via Nanopore Long-Read Sequencing

Editorial: Insights in human and medical genomics 2024

Functional validation of the novel KIF5A p.R17Q VUS reveals defective axonal transport in iPSC-motoneurons from a SPG10 patient

Navigating Tensions between Scientific Advancement and Ethical Practice in Biobanking: A Qualitative Study in Japan

Promoter hypomethylation of CDH7: a novel epigenetic marker associated with cerebral small vessel disease

Geneticization outside genetics’ birthplace: ethical, legal and social implications in the Gulf Cooperation Council region

A SCN1A missense variant (c.4522T>A, p.(Tyr1508Asn) associated with genetic epilepsy with febrile seizures plus: clinical phenotype and genetic analysis of a Chinese pedigree

Editorial: Advancements in sequencing technologies for epigenomic and transcriptomic analysis: from bulk to single-cell resolution

Novel LARS2 variants in patients with Perrault syndrome: expanding the genetic spectrum and phenotypic heterogeneity

Case Report: Identification of a de novo missense variant in the N-terminal zinc-finger domain of ZEB2 in a patient presenting with neurodevelopmental delay and recurrent pulmonary infections

Plastic film mulching enhances flavonoid accumulation in the roots of Scutellaria baicalensis

Identification of gene expression signatures associated with neuroinflammation in discogenic sciatica using machine learning and experimental validation

Whole-genome sequencing reveals genomic diversity and selection signatures for adaptation in South African Afrikaner and Bonsmara cattle

Case Report: Expanding the diagnostic spectrum of non-invasive prenatal testing to structural chromosomal abnormalities

BHLHE41–SLC7A11 transcriptional axis and chromatin remodeling signatures in osteogenic-lineage disulfidptosis-like stress in osteoporosis

GViT-GP: Injecting the Genomic Relationship Matrix as an Inductive Bias into a Vision Transformer via Cross-Attention for Genomic Prediction

Potential effects on the signaling network mediated by overexpression of the vitronectin gene in Hu sheep ruminal epithelial cells using multi-omics analysis

Glycolysis-related gene signatures in spinal cord injury pathophysiology identification through integrative gene expression analysis

Editorial: Integrating genetics and proteomics for drug discovery

Correction: Population genetics of Plasmodium vivax with transmission decline and rebound in two endemic areas of Papua New Guinea

Editorial: Insights in applied genetic epidemiology 2025

Differentially expressed proteins in plasma-derived extracellular vesicles from chronic myeloid leukemia patients