Frontiers in Genetics

Original Research

Accepted on 15 Sep 2025

Whole Exome Sequencing Identifies Concurrent LDLR and ABCG8 Mutations in a Saudi Family with Familial hypercholesterolemia and Sitosterolaemia

Abdulrahman Hummadi
Dhayf Alrahman Mutawwam
Jumana Y Al-Aama
Fai Alsubhi
NAJI ALJOHANI
Ali J Alhagawy
Turki Algohani
Ebraheem Fallatah
Mohammed Y Daghriry
Rawan K Alharbi

Frontiers in Genetics

doi 10.3389/fgene.2025.1679594

Original Research

Accepted on 15 Sep 2025

Identification and validation of calcium signaling pathway-related biomarkers in T1 and T2 lymph node metastatic gastric cancer

Mingzhi Cai
Xinyang Nie
Fenglin Cai
Xiuding Yang
Weilin Sun
Rupeng Zhang
Han Liang
Li Zhang
Yonglin Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1653700

Original Research

Accepted on 15 Sep 2025

Immune-Molecular Nexus in Reproductive Disorders: Mechanisms Linking POI and RSA

Chen Chen
Xiaolan Zhu
Xinyue Zhang
Subo Zhang
Wenxin Li
Yueqin Liu
Zhao Dan

Frontiers in Genetics

doi 10.3389/fgene.2025.1652519

Original Research

Accepted on 15 Sep 2025

Analyzes of Haplotypes of TLR2 and TLR3 genes for COVID-19 Prognosis in a Cohort of Professionals who Worked in the 1st Pandemic Wave in Belém-PA, Brazil

Marcos Jessé Abrahão Silva
Luiza Raquel Tapajós Figueira
Daniele Melo Sardinha
Natasha Cristina Oliveira Andrade
Sebastião Kauã De Sousa Bispo
Thiago Augusto Ferreira Dos Anjos
Everaldina Cordeiro dos Santos
Ana Judith Pires Garcia
Luana Nepomuceno Gondim Costa Lima

Frontiers in Genetics

doi 10.3389/fgene.2025.1659269

Original Research

Accepted on 15 Sep 2025

Prenatal Diagnosis and Molecular Characterization of PKHD1 Variants in two Chinese Fetuses with Caroli Disease/Syndrome

Hui Huang
Sheng Zhao
Dan Wang
Shengbao Pan
Fang Liu
Peiwen Chen
Xinlin Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1651306

Original Research

Published on 15 Sep 2025

Characterization of the phenotype and function of PRELP+ fibroblast subtype in liver metastatic colorectal cancer

Yuting Dai
Xingying Huang
Min Sun
Shiyu Zhang
Weiqiang Yu
Kongwang Hu
Qiang Wu
Qingfa Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1615259

332 views

Original Research

Published on 15 Sep 2025

Functional characterization of MFSD3 in auditory system and zebrafish embryogenesis

Ying Ma
Shi-Wei Qiu
Wei-Qian Wang
Hai-Feng Feng
Lu Zheng
Ge-Ge Wei
Hui-Yi Nie
Jin-Yuan Yang
Yi-Jin Chen
Pu Dai

Frontiers in Genetics

doi 10.3389/fgene.2025.1634493

224 views

Original Research

Published on 15 Sep 2025

Personalized skin health management and nutrition strategies: a comprehensive study based on genetic polymorphisms and dietary factors

Jitao Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1624960

528 views

Methods

Published on 15 Sep 2025

Construction of a novel prognostic model for gastric cancer based on pharmacokinetics-related genes and comprehensive prognostic analysis

Yu Zhang
Kai Jia
Yuntong Guo
Xiaole Ma
Tian Yao
Feng Wu
He Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1541401

203 views

Opinion

Published on 15 Sep 2025

The potential clinical and public health implications of presymptomatic genetic testing for transthyretin amyloidosis in African American/Black adults in the United States

Inderjeet Bharaj
Simar J. Singh
Juzer Munaim
Harneet Grewal
Sonia Sabrowsky
Andrew Boshara
Marc A. Silver
Katherine H. Brendish
Paul Underwood
Sandesh Dev

Frontiers in Genetics

doi 10.3389/fgene.2025.1658636

996 views

Review

Accepted on 12 Sep 2025

Mechanisms of Circular RNAs in Diabetic Cardiomyopathy: Biological Characteristics and Clinical Prospects

Yunfei Guan
Quancheng Han
Meng Wang
Jianguo Xu
Xiujuan Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1665571

345 views

Original Research

Accepted on 12 Sep 2025

LncRNA and mRNA expression characteristic and bioinformatic analysis in Anemic Diabetic Foot Ulcers

Jiayu Lin
Jingying Wang
Bo Liang

Frontiers in Genetics

doi 10.3389/fgene.2025.1603315

Original Research

Published on 12 Sep 2025

Dissecting and validation the biomarker of heart failure progression in patients with atherosclerosis by single-cell sequencing, bioinformatics, and machine learning

Lihua Ni
Huabo Li
Juan Du
Ke Zhou
Fugui Zhang
Liankai Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1587274

589 views

Original Research

Published on 12 Sep 2025

Whole-exome sequencing in pediatric patients with glomerulonephritis

Marina Peric
Marija Brankovic
Natasa Stajic
Jovana Putnik
Aleksandra Paripovic
Milena Jankovic
Dejan Nikolic
Filip Milanovic
Ivana Novakovic
Vladislav Vukomanovic

Frontiers in Genetics

doi 10.3389/fgene.2025.1611340

590 views

Mini Review

Accepted on 11 Sep 2025

Recent Progress of DNA Methylation in Psoriasis

Zhaoping Lin
Xiaoting Wu
Xuqin Hong
Dongying Luo
Hui Li
Fei Ma
Cong Huang
Bo Yu
Jing Gao
Changbing Shen

Frontiers in Genetics

doi 10.3389/fgene.2025.1681666

344 views

Original Research

Accepted on 11 Sep 2025

HFTC: A Hierarchical Fungal Taxonomic Classification Model for ITS Sequences Using Low-Dimensional Embedding Features

Jiawei Wang
Shaojie Qiao
Chao Wang
Dongsheng Xiang
Yangcheng Liao

Frontiers in Genetics

doi 10.3389/fgene.2025.1650244

336 views

16,213 Publications

Volume 16 - 2025

Whole Exome Sequencing Identifies Concurrent LDLR and ABCG8 Mutations in a Saudi Family with Familial hypercholesterolemia and Sitosterolaemia

Identification and validation of calcium signaling pathway-related biomarkers in T1 and T2 lymph node metastatic gastric cancer

Immune-Molecular Nexus in Reproductive Disorders: Mechanisms Linking POI and RSA

Analyzes of Haplotypes of TLR2 and TLR3 genes for COVID-19 Prognosis in a Cohort of Professionals who Worked in the 1st Pandemic Wave in Belém-PA, Brazil

Prenatal Diagnosis and Molecular Characterization of PKHD1 Variants in two Chinese Fetuses with Caroli Disease/Syndrome

Characterization of the phenotype and function of PRELP+ fibroblast subtype in liver metastatic colorectal cancer

Functional characterization of MFSD3 in auditory system and zebrafish embryogenesis

Personalized skin health management and nutrition strategies: a comprehensive study based on genetic polymorphisms and dietary factors

Construction of a novel prognostic model for gastric cancer based on pharmacokinetics-related genes and comprehensive prognostic analysis

The potential clinical and public health implications of presymptomatic genetic testing for transthyretin amyloidosis in African American/Black adults in the United States

Mechanisms of Circular RNAs in Diabetic Cardiomyopathy: Biological Characteristics and Clinical Prospects

LncRNA and mRNA expression characteristic and bioinformatic analysis in Anemic Diabetic Foot Ulcers

Dissecting and validation the biomarker of heart failure progression in patients with atherosclerosis by single-cell sequencing, bioinformatics, and machine learning

Whole-exome sequencing in pediatric patients with glomerulonephritis

Recent Progress of DNA Methylation in Psoriasis

HFTC: A Hierarchical Fungal Taxonomic Classification Model for ITS Sequences Using Low-Dimensional Embedding Features