Frontiers in Genetics

Original Research

Accepted on 10 Oct 2025

Construction of a HSC activation-related lncRNA-miRNA-mRNA ceRNA regulatory network reveals potential molecules involved in liver fibrosis

Kaiqiang Wan
Qiong Zhou
Ruirui Feng
Tao Liu
Chang Fan
Xue Pang
Zhongliang Li
Qiumei Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1640326

183 views

Original Research

Accepted on 10 Oct 2025

Application of Trio-based Whole-Exome Sequencing in Fetal Ultrasound Anomalies: A Single-Center Retrospective Study of 454 Cases

Dongyi Yu
Dairong Feng
Jiangbo Qu
Lei Nie
Qian Liu
Lu Gao
Wenzhen An
Na Liu
Yuying Fang

Frontiers in Genetics

doi 10.3389/fgene.2025.1662801

215 views

Case Report

Accepted on 10 Oct 2025

Identification and functional characterization of a novel heterozygous splice-donor (c.647+1G>A) site mutation in SPTB gene causes hereditary spherocytosis with hemolytic anemia

KE CAO
Xiaojuan Luo
Lianlian Liu
Xiaoning Mao
Ruping Liu
Yunsheng Chen
Prof. (Dr.) Santasree Banerjee

Frontiers in Genetics

doi 10.3389/fgene.2025.1626155

145 views

Case Report

Published on 10 Oct 2025

Case Report: Practical approach to differentiating juvenile parkinsonism of genetic cause and drug-induced parkinsonism in adolescents: a case series and literature review

Ioana Grigore
Lăcrămioara Ionela Butnariu
Thomas Gabriel Schreiner
Vasile Valeriu Lupu
Ancuta Lupu
Ludmila Darie
Cătălin Prăzaru
Elena Țarcă
Setalia Popa
Ecaterina Grigore

Frontiers in Genetics

doi 10.3389/fgene.2025.1672445

444 views

Original Research

Accepted on 09 Oct 2025

Multi-Omics Identification and Validation of Oxidative Phosphorylation–Related Hub Genes in Schizophrenia

Yu Zhou
Shuang Zhang
Yaoxia Liu
Xin Dai
Ting Zhang
Xiao-Tao Xu
Sheng-Nan Deng
Min-Yan Yang
Fan Zhen

Frontiers in Genetics

doi 10.3389/fgene.2025.1690947

141 views

Original Research

Accepted on 09 Oct 2025

Identification and functional analysis of a novel CSNK2A1 frameshift variant in stillbirth: a case report

Nannan Zhang
Miao Han
Tong Zhao
Xinxin Tang
Zhiwei Wang
Yunqiu Du
Leilei Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1692704

Case Report

Accepted on 09 Oct 2025

Case report: Identification of a Novel 9.159-kb Deletion in a Chinese α-Thalassemia Family Using Single Molecule Real-Time Technology Sequencing

Wu Shulin
Feng Zonghui
Jiang Fuxiang
Zhao Min
Jiang Peng
Xiao Gang
Zhang Xian

Frontiers in Genetics

doi 10.3389/fgene.2025.1669814

Editorial

Published on 09 Oct 2025

Editorial: Application of next-generation sequencing in clinical settings

Zhi Chai
Han Mei
Quan Li
Iram Maqsood
Jingxian Cai
Marilyn M. Li
Feng Xu
Xiaonan Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1700975

1,226 views

Original Research

Published on 09 Oct 2025

The molecular characterization of seven novel GLI family zinc finger 3 (GLI3) variants in Chinese families with limb malformations

Siyuan Tao
Xuyu Gu
Xiaodong Wang
Xiaofang Shen
Xiuli Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1650790

560 views

Review

Accepted on 08 Oct 2025

Ocular Surface Health and Disease: Insight from Single-cell RNA Sequencing

Shangkun Ou
Minqing Cai
Yuchong Feng
Sijie Lin
Xueer Zheng
Su Zhao
Hao Gu
Yiming Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1683167

156 views

Original Research

Published on 08 Oct 2025

GTAT-GRN: a graph topology-aware attention method with multi-source feature fusion for gene regulatory network inference

Shuran Wang
Lilian Zhang
Lutao Gao
Yao Rao
Jie Cui
Linnan Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1668773

972 views

Original Research

Published on 08 Oct 2025

Integrated transcriptomic and single-cell RNA sequencing identifies lysosomal ion channel genes as potential biomarkers for Alzheimer’s disease

Xin Wang
Zelin Wu
Shaoli Wei
Xinran Zhao
Juan Lin
Fang Zhao
Xiaolei Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1676565

663 views

Data Report

Published on 08 Oct 2025

Catalogue of mitotic chromosome-associated small RNAs in mouse 3T3 cell line

Bishan Ye
Yicong Meng
Le Zhang
Yongzhuo Deng
Xuesong Zheng
Yihang Shen
Xinhui Li
Hua Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1559795

646 views

Perspective

Published on 08 Oct 2025

Ethical, legal, and policy dimensions and contentions for reanalysis and reinterpretation of clinical genetic testing results

Zachary T. Sentell
Ma’n H. Zawati

Frontiers in Genetics

doi 10.3389/fgene.2025.1685854

584 views

Review

Published on 08 Oct 2025

Epigenetic and metabolic reprogramming via nanotechnology: a synergistic approach to cancer vaccination in lung tumors

Min Xu
Xialin Zhang
Xinlin Yu
Cheng Ma
Xinwei Li
Gang Chen
Gang Yuan
Sheng Lin
Ran Cui

Frontiers in Genetics

doi 10.3389/fgene.2025.1666561

686 views

Original Research

Published on 08 Oct 2025

Pain - related methylation driver genes affect the prognosis of pancreatic cancer patients by altering immune function and perineural infiltration

Chencheng Zhang
Weiwei Xu
Xudong Chen
Xingdan Wang
Xiaopeng Cui
Wenjing Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1600883

604 views

16,286 Publications

Volume 16 - 2025

Construction of a HSC activation-related lncRNA-miRNA-mRNA ceRNA regulatory network reveals potential molecules involved in liver fibrosis

Application of Trio-based Whole-Exome Sequencing in Fetal Ultrasound Anomalies: A Single-Center Retrospective Study of 454 Cases

Identification and functional characterization of a novel heterozygous splice-donor (c.647+1G>A) site mutation in SPTB gene causes hereditary spherocytosis with hemolytic anemia

Case Report: Practical approach to differentiating juvenile parkinsonism of genetic cause and drug-induced parkinsonism in adolescents: a case series and literature review

Multi-Omics Identification and Validation of Oxidative Phosphorylation–Related Hub Genes in Schizophrenia

Identification and functional analysis of a novel CSNK2A1 frameshift variant in stillbirth: a case report

Case report: Identification of a Novel 9.159-kb Deletion in a Chinese α-Thalassemia Family Using Single Molecule Real-Time Technology Sequencing

Editorial: Application of next-generation sequencing in clinical settings

The molecular characterization of seven novel GLI family zinc finger 3 (GLI3) variants in Chinese families with limb malformations

Ocular Surface Health and Disease: Insight from Single-cell RNA Sequencing

GTAT-GRN: a graph topology-aware attention method with multi-source feature fusion for gene regulatory network inference

Integrated transcriptomic and single-cell RNA sequencing identifies lysosomal ion channel genes as potential biomarkers for Alzheimer’s disease

Catalogue of mitotic chromosome-associated small RNAs in mouse 3T3 cell line

Ethical, legal, and policy dimensions and contentions for reanalysis and reinterpretation of clinical genetic testing results

Epigenetic and metabolic reprogramming via nanotechnology: a synergistic approach to cancer vaccination in lung tumors

Pain - related methylation driver genes affect the prognosis of pancreatic cancer patients by altering immune function and perineural infiltration