Frontiers in Medicine | Hepatobiliary Diseases

Original Research

Published on 27 Jan 2026

Successful long-term results (> 5 years) of superselective transarterial chemoembolization in symptomatic/enlarging liver hemangiomas: a paradigm shift at a hepatopancreatobiliary surgery unit

in Hepatobiliary Diseases

İlgin Özden
Arzu Poyanlı
Cem İbiş
Bülent Acunaş

Frontiers in Medicine

doi 10.3389/fmed.2026.1699596

472 views

Original Research

Accepted on 26 Jan 2026

An Interpretable Machine Learning Model with SHAP Explanations Predicts Spontaneous Bleeding in Pediatric Acute Liver Failure

in Hepatobiliary Diseases

Qiang Xiong
Ruijue Wang
Chenyu Yang
Mingman Zhang

Frontiers in Medicine

152 views

Case Report

Published on 22 Jan 2026

Experience with hepatectomy in a patient with focal nodular hyperplasia combining with constitutional indocyanine green excretory defect: a case report

in Hepatobiliary Diseases

Tengfei Wang
Yunyi Li
Xiaodong Sun
Guoyue Lv

Frontiers in Medicine

doi 10.3389/fmed.2026.1675917

468 views

Original Research

Published on 22 Jan 2026

A simple score of sarcopenic obesity predicts all-cause mortality in patients with cirrhosis

in Hepatobiliary Diseases

Yuteng Yang
Tingyang Wei
Shuo Yang
Ran Fei
Changjie Tie
Rui Han
Danli Ma
Qian Jin
Jian Wang
Zixing Wang

Frontiers in Medicine

doi 10.3389/fmed.2026.1719899

388 views

Original Research

Published on 21 Jan 2026

Liver fibrosis in biliary atresia: identification of the key gene EDIL3 via integrated bioinformatics

in Hepatobiliary Diseases

Meng Kong
Jinhua Jia
Chuanyang Liu
Hongzhen Liu
Shisong Zhang

Frontiers in Medicine

doi 10.3389/fmed.2025.1726141

692 views

Original Research

Published on 21 Jan 2026

Beyond traditional—the sick cirrhosis patient scores integrating cytokine and immune profiling for precision prognosis in hospitalized cirrhosis patients may help predict infection, ICU admission and long-term death post hospitalization

in Hepatobiliary Diseases

Cyriac Abby Philips
Tharun Tom Oommen
Arif Hussain Theruvath
Aryalakshmi Sreemohan
Ambily Baby
Ansu Abu Alex
Sunitha Thomas
Sunitha Mary John
Rizwan Ahamed
Ajit Tharakan

Frontiers in Medicine

doi 10.3389/fmed.2026.1736956

736 views

Clinical Trial

Accepted on 20 Jan 2026

A novel dual elastography-based model for screening high-risk varices in hepatitis B virus-related cirrhosis

in Hepatobiliary Diseases

Xing Hu
Min Chen
Ying Zheng
Xiuhua Yang
Wei Zhang
Yao Zhang
Zhiyong Yin
Jintang Liao
Yangshuo Tang
Jie Yu

Frontiers in Medicine

262 views

Review

Published on 20 Jan 2026

Effect of SGLT-2 inhibitors on liver fibrosis progression in patients with MASLD: an updated meta-analysis based on RCTs

in Hepatobiliary Diseases

Lei Yang
Jiale Ruan
Yingying Fang
Anyi Xu

Frontiers in Medicine

doi 10.3389/fmed.2025.1667823

894 views

Case Report

Published on 16 Jan 2026

Beyond pruritus in Alagille syndrome: potential effects of maralixibat on fibrosis and portal hypertension–insights from two case studies

in Hepatobiliary Diseases

Jesús Quintero-Bernabeu
Cristina Padrós-Fornieles
Maria Mercadal-Hally
Mauricio Larrarte-King
Simone Mameli
Mar Miserachs-Barba
Lis Vidal-Valdivia
José Andrés Molino-Gahete
Antonio Moreno-Galdo

Frontiers in Medicine

doi 10.3389/fmed.2025.1707258

799 views

Review

Published on 16 Jan 2026

Artificial intelligence in hepatocellular carcinoma screening: applications and challenges

in Hepatobiliary Diseases

Jian-Xu Rao
Ying Li
Kai Leng

Frontiers in Medicine

doi 10.3389/fmed.2025.1713887

938 views

Review

Published on 15 Jan 2026

Gut–liver–muscle axis: linking gut microbiota dysbiosis to malnutrition and sarcopenia in liver disease

in Hepatobiliary Diseases

Hongjing Zhao
Yang Liu
Linhao Su
Panpan Cui
Jinhai Sai
Sijin Li
Na Wang
Peiyuan He

Frontiers in Medicine

doi 10.3389/fmed.2025.1727270

1,126 views

Systematic Review

Published on 15 Jan 2026

Diagnostic potential of salivary biomarkers for primary biliary cholangitis: a systematic review

in Hepatobiliary Diseases

Mahnoor Saeed
Muhammad Saad Shaikh
Alhanouf Binhezaim
Tahani Almutairi
Mohid Abrar Lone
Syed Jawad Ali Bukhari
Muhammad Sohail Zafar

Frontiers in Medicine

doi 10.3389/fmed.2025.1670206

956 views

Original Research

Published on 14 Jan 2026

Development of a machine learning model for hepatic steatosis screening using non-invasive Traditional Chinese Medicine diagnostics and clinical variables: a health checkup study with community screening potential

in Hepatobiliary Diseases

Ke Zhu
Lihua Li
Zhihui Zhao
Sheng Zheng
Bing Lin
Wenjun Tang
Weihong Li

Frontiers in Medicine

doi 10.3389/fmed.2025.1704441

666 views

Case Report

Accepted on 13 Jan 2026

Polysplenia Syndrome Complicated by Multiple Intrahepatic Bile Duct Stones in an Adult: A Case Report

in Hepatobiliary Diseases

Jiahao Zhang
Jiliang Lu
Hongzhong Liang
Pengyu Chen
Zheng Wang
Naiqing Liu
Jinghua Liu

Frontiers in Medicine

115 views

Original Research

Published on 13 Jan 2026

A novel homozygous splice-site variant in the FOCAD gene causing infantile liver cirrhosis and neutropenia: expanding disease phenotype and successful surgical treatment

in Hepatobiliary Diseases

Ekaterina Nuzhnaya
Elena Zaklyazminskaya
Viktoriia Zabnenkova
Darya Akimova
Evgeny Tatarsky
Lana Dzik
Andrey Surkov
Natalia Zhurkova
Andrey Filin
Aleksej Metelin

Frontiers in Medicine

doi 10.3389/fmed.2025.1680857

700 views

Original Research

Published on 12 Jan 2026

Prevalence and clinical relevance of sarcopenia in Chinese patients with porto-sinusoidal vascular disorder

in Hepatobiliary Diseases

Jiaxin Chen
Xin Quan
Shuaijie Qian
Yang Tai
Zhidong Wang
Huan Tong
Jinhang Gao
Bo Wei
Hao Wu

Frontiers in Medicine

doi 10.3389/fmed.2025.1756842

515 views

Original Research

Published on 12 Jan 2026

Non-invasive assessment of liver fibrosis staging in chronic hepatitis B patients: combining two-dimensional shear wave elastography with serum indicators

in Hepatobiliary Diseases

Yaoren Zhang
Jianjun Yang
Qinyun Wan
Lu Gan
Jianxue Liu

Frontiers in Medicine

doi 10.3389/fmed.2025.1709007

673 views

Original Research

Published on 12 Jan 2026

Prophylactic use of a combination of palonosetron hydrochloride and dexamethasone to prevent transcatheter arterial chemoembolization-induced nausea and vomiting among patients with hepatocellular carcinoma

in Hepatobiliary Diseases

Wei-Mei Zhang
Meng-Jing Zheng
Cheng Li
Lei-Lei Chen
Chang Yu
Jiang-Fan Zhou
Jie Zheng

Frontiers in Medicine

doi 10.3389/fmed.2025.1643731

504 views

Case Report

Published on 12 Jan 2026

Sump syndrome following hepaticojejunostomy: a case report of IgG4-related sclerosing cholangitis

in Hepatobiliary Diseases

Liqin Ruan
Weili Chen
HanYing Mei

Frontiers in Medicine

doi 10.3389/fmed.2025.1730125

651 views

Original Research

Published on 12 Jan 2026

Comparison of inflammatory markers and microflora in cirrhotic patients with portal vein thrombosis: a retrospective study

in Hepatobiliary Diseases

Yanzhao Sun
Cunkai Wang
Dingxin Wang
Hongtao Hou
Jian Zhang
Yueqin Li
Yun Bai

Frontiers in Medicine

doi 10.3389/fmed.2025.1680970

427 views

Original Research

Published on 12 Jan 2026

Proposing preoperative neutrophil percentage-to-albumin ratio as an effective prognostic factor for postoperative prognosis of distal cholangiocarcinoma: a retrospective cohort study

in Hepatobiliary Diseases

Han-xuan Wang
Zu-yu Wang
Shao-cheng Lyu
Jin-can Huang
Qiang He
Ren Lang
Tao Jiang

Frontiers in Medicine

doi 10.3389/fmed.2025.1725834

507 views

Original Research

Published on 12 Jan 2026

Hybrid intelligent systems for liver disease prediction: a demographic-aware machine learning framework

in Hepatobiliary Diseases

Ekta Saraf
Mao Yang
Ramalingam Sakthivel
Yiquan Zhang
Santosh Chokkakula
Yu Kong
Vykunta Alekya
Bommireddy Naveen
Bing Yang

Frontiers in Medicine

doi 10.3389/fmed.2025.1728061

918 views

Original Research

Published on 12 Jan 2026

Clinical characteristics and outcomes in 50 children with autoimmune hepatitis: a retrospective study from a single centre in China

in Hepatobiliary Diseases

Yandi Yang
Fan Yang
Min Yang
Zherui Liu
Shuhong Liu
Linlin Lian
Binxia Chang
Lijun Shen
Hua Tian
Qingsheng Liang

Frontiers in Medicine

doi 10.3389/fmed.2025.1733006

957 views

Case Report

Published on 09 Jan 2026

Strangulated cholecystitis in an umbilical hernia: world-first case report

in Hepatobiliary Diseases

Marco Brolese
Matteo Pittacolo
Arianna Vittori
Gianpietro Zanchettin
Renato Salvador
Valeria Valli
Lorenzo Vallese
Nicola Baldan
Gianfranco Da Dalt
Michele Valmasoni

Frontiers in Medicine

doi 10.3389/fmed.2025.1684301

1,284 views

410 articles

articles

Successful long-term results (> 5 years) of superselective transarterial chemoembolization in symptomatic/enlarging liver hemangiomas: a paradigm shift at a hepatopancreatobiliary surgery unit

An Interpretable Machine Learning Model with SHAP Explanations Predicts Spontaneous Bleeding in Pediatric Acute Liver Failure

Experience with hepatectomy in a patient with focal nodular hyperplasia combining with constitutional indocyanine green excretory defect: a case report

A simple score of sarcopenic obesity predicts all-cause mortality in patients with cirrhosis

Liver fibrosis in biliary atresia: identification of the key gene EDIL3 via integrated bioinformatics

Beyond traditional—the sick cirrhosis patient scores integrating cytokine and immune profiling for precision prognosis in hospitalized cirrhosis patients may help predict infection, ICU admission and long-term death post hospitalization

A novel dual elastography-based model for screening high-risk varices in hepatitis B virus-related cirrhosis

Effect of SGLT-2 inhibitors on liver fibrosis progression in patients with MASLD: an updated meta-analysis based on RCTs

Beyond pruritus in Alagille syndrome: potential effects of maralixibat on fibrosis and portal hypertension–insights from two case studies

Artificial intelligence in hepatocellular carcinoma screening: applications and challenges

Gut–liver–muscle axis: linking gut microbiota dysbiosis to malnutrition and sarcopenia in liver disease

Diagnostic potential of salivary biomarkers for primary biliary cholangitis: a systematic review

Development of a machine learning model for hepatic steatosis screening using non-invasive Traditional Chinese Medicine diagnostics and clinical variables: a health checkup study with community screening potential

Polysplenia Syndrome Complicated by Multiple Intrahepatic Bile Duct Stones in an Adult: A Case Report

A novel homozygous splice-site variant in the FOCAD gene causing infantile liver cirrhosis and neutropenia: expanding disease phenotype and successful surgical treatment

Prevalence and clinical relevance of sarcopenia in Chinese patients with porto-sinusoidal vascular disorder

Non-invasive assessment of liver fibrosis staging in chronic hepatitis B patients: combining two-dimensional shear wave elastography with serum indicators

Prophylactic use of a combination of palonosetron hydrochloride and dexamethasone to prevent transcatheter arterial chemoembolization-induced nausea and vomiting among patients with hepatocellular carcinoma

Sump syndrome following hepaticojejunostomy: a case report of IgG4-related sclerosing cholangitis

Comparison of inflammatory markers and microflora in cirrhotic patients with portal vein thrombosis: a retrospective study

Proposing preoperative neutrophil percentage-to-albumin ratio as an effective prognostic factor for postoperative prognosis of distal cholangiocarcinoma: a retrospective cohort study

Hybrid intelligent systems for liver disease prediction: a demographic-aware machine learning framework

Clinical characteristics and outcomes in 50 children with autoimmune hepatitis: a retrospective study from a single centre in China

Strangulated cholecystitis in an umbilical hernia: world-first case report