In the published article, there was an error in Figure 7 as published. The Figures 7, 8 were mixed up. The corrected Figure 7 and its caption appear below.
FIGURE 7
Structural alterations of Dicer1 variant F508C. (A) Interactions formed by wild-type amino acid F508. (B) Interactions formed by mutation C508. Amino acids taking part in bond formation are marked by spheres. H-bonds are indicated by dashed yellow lines, and aromatic H-bonds are indicated by dashed blue lines. Protein secondary structural elements (α-helixes, β-strands, and disordered loops) are shown in blue by cartoon representation. The radius of gyration (C) and RMSD (D) fluctuations of the 10 Å region around the wild-type amino acid and corresponding mutation through a 300-ns MD simulation.
In the published article, there was an error in Figure 8 as published. The Figures 7, 8 were mixed up. The corrected Figure 8 and its caption appear below.
FIGURE 8
Structural alterations of Dicer1 variant T993R. (A) Interactions formed by wild-type amino acid T993. (B) Interactions formed by mutation R993. Amino acids taking part in bond formation are marked by spheres. H-bonds are indicated by dashed yellow lines, and aromatic H-bonds are indicated by dashed blue lines. Protein secondary structural elements (α-helixes, β-strands, and disordered loops) are shown in blue by cartoon representation. The radius of gyration (C) and RMSD (D) fluctuations of the 10 Å region around the wild-type amino acid and corresponding mutation through a 300-ns MD simulation.
The authors apologize for these error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Statements
Publisher’s note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.
Summary
Keywords
Dicer1, variant of uncertain significance, variant effect prediction, gene evolution, oncology, molecular dynamics
Citation
Bug DS, Moiseev IS, Porozov YB and Petukhova NV (2024) Corrigendum: Shedding light on the DICER1 mutational spectrum of uncertain significance in malignant neoplasms. Front. Mol. Biosci. 11:1517143. doi: 10.3389/fmolb.2024.1517143
Received
25 October 2024
Accepted
11 November 2024
Published
28 November 2024
Volume
11 - 2024
Edited and reviewed by
Annalisa Pastore, King’s College London, United Kingdom
Updates
Copyright
© 2024 Bug, Moiseev, Porozov and Petukhova.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: N. V. Petukhova, petuhovanv@1spbgmu.ru
Disclaimer
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.