Frontiers in Molecular Biosciences

Original Research

Published on 11 Jan 2024

Classification of clinically actionable genetic mutations in cancer patients

in Molecular Diagnostics and Therapeutics

Muhammad Shahzad
Muhammad Rafi
Wadee Alhalabi
Naz Minaz Ali
Muhammad Shahid Anwar
Sara Jamal
Muskan Barket Ali
Fahad Abdullah Alqurashi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1277862

3,364 views
1 citation

Original Research

Published on 11 Jan 2024

Loss of filamentous actin, tight junction protein expression, and paracellular barrier integrity in frataxin-deficient human brain microvascular endothelial cells—implications for blood-brain barrier physiology in Friedreich’s ataxia

in Lipids, Membranes and Membranous Organelles

Frances M. Smith
Daniel J. Kosman

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1299201

3,495 views
3 citations

Original Research

Published on 11 Jan 2024

Leveraging machine learning for taxonomic classification of emerging astroviruses

in Structural Biology

Fatemeh Alipour
Connor Holmes
Yang Young Lu
Kathleen A. Hill
Lila Kari

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1305506

5,788 views
4 citations

Original Research

Published on 11 Jan 2024

The analysis of low-dose glucocorticoid maintenance therapy in patients with primary nephrotic syndrome suffering from COVID-19

in Protein Biochemistry for Basic and Applied Sciences

Yong-Qi Li
Min Wu
Yu-Jia Wang
Yu-Xia Zhang
Jing Lu
Yi-Nan Zhao
Bo-Fan Ji
Zhi-Qing Chen
Ri-Ning Tang
Bi-Cheng Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1326111

2,003 views

Original Research

Published on 11 Jan 2024

Pan-cancer analysis of SERPINE family genes as biomarkers of cancer prognosis and response to therapy

in Molecular Diagnostics and Therapeutics

Yating Liu
Xinyu Li
Shanshan Chen
Changyu Zhu
Yijun Shi
Shoutao Dang
Weitao Zhang
Wei Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1277508

4,289 views
9 citations

Original Research

Published on 11 Jan 2024

Generation of human TMEM16F-specific affibodies using purified TMEM16F

in Molecular Recognition

Eunyoung Kim
Jinho Bang
Ji Hye Sung
Jonghwan Lee
Dae Hwan Shin
Sunghyun Kim
Byoung-Cheol Lee

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1319251

3,466 views

Original Research

Published on 11 Jan 2024

Proteomic analysis of holocarboxylase synthetase deficient-MDA-MB-231 breast cancer cells revealed the biochemical changes associated with cell death, impaired growth signaling, and metabolism

in Cellular Biochemistry

Witchuda Sukjoi
Clifford Young
Mitchell Acland
Siraprapa Siritutsoontorn
Sittiruk Roytrakul
Manuela Klingler-Hoffmann
Peter Hoffmann
Sarawut Jitrapakdee

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1250423

3,034 views
2 citations

Original Research

Published on 11 Jan 2024

Computational analysis of RNA methyltransferase Rv3366 as a potential drug target for combating drug-resistant Mycobacterium tuberculosis

in Structural Biology

Tasmin Nazim
Vipul Kumar
Faraz Ahmed
Nasreen Z. Ehtesham
Seyed E. Hasnain
Durai Sundar
Sonam Grover

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1348337

2,526 views
3 citations

Editorial

Published on 11 Jan 2024

Editorial: Novel drug-designing approaches to combat antimicrobial resistance

in Biological Modeling and Simulation

Ghazala Muteeb
Md Tabish Rehman
Bibhusita Pani
Rizwan Hasan Khan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1342702

2,677 views
7 citations

Original Research

Published on 11 Jan 2024

A computational examination of the therapeutic advantages of fourth-generation ALK inhibitors TPX-0131 and repotrectinib over third-generation lorlatinib for NSCLC with ALK F1174C/L/V mutations

in Molecular Recognition

Ambritha Balasundaram
George Priya C. Doss

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1306046

4,361 views
3 citations

Original Research

Published on 11 Jan 2024

A MALDI-TOF mass spectrometry-based method for detection of copy number variations in BRCA1 and BRCA2 genes

in Molecular Diagnostics and Therapeutics

Hongjun Zhou
Xin He
Jiadong Zhao
Zhu Mei
Xiayan Zhang
Wen Yuan
Hui Dong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1301652

2,201 views
2 citations

Original Research

Published on 11 Jan 2024

Exploring the inhibitory potential of in silico-designed small peptides on Helicobacter pylori Hp0231 (DsbK), a periplasmic oxidoreductase involved in disulfide bond formation

in Protein Biochemistry for Basic and Applied Sciences

Paula Roszczenko-Jasińska
Artur Giełdoń
Dominika Mazur
Marta Spodzieja
Maciej Plichta
Cezary Czaplewski
Wojciech Bal
Elzbieta K. Jagusztyn-Krynicka
Dariusz Bartosik

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1335704

3,213 views
1 citation

Original Research

Published on 10 Jan 2024

The IRAK-M death domain: a tale of three surfaces

in Molecular Recognition

Berke Gürkan
Hessel Poelman
Liza Pereverzeva
Danielle Kruijswijk
Alex F. de Vos
Anouk G. Groenen
Edgar E. Nollet
Kanin Wichapong
Esther Lutgens
Tom van der Poll

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1265455

3,022 views
2 citations

Original Research

Published on 10 Jan 2024

Construction of shared gene signature between rheumatoid arthritis and lung adenocarcinoma helps to predict the prognosis and tumor microenvironment of the LUAD patients

in Molecular Diagnostics and Therapeutics

Liping Shi
Houwen Zou
Jian Yi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1314753

2,953 views
1 citation

Original Research

Published on 10 Jan 2024

Comparative transcriptomic insights into the domestication of Pleurotus abieticola for coniferous cultivation

in Biological Modeling and Simulation

Lei Sun
Frederick Leo Sossah
Yu Li
Huiying Sun

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1352163

1,591 views
1 citation

Review

Published on 09 Jan 2024

The role of non-coding RNAs in muscle aging: regulatory mechanisms and therapeutic potential

in RNA Networks and Biology

Yeo Jin Shin
Ki-Sun Kwon
Yousin Suh
Kwang-Pyo Lee

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1308274

4,121 views
8 citations