Frontiers in Molecular Biosciences

Original Research

Published on 12 Aug 2024

Leveraging multi-omics data to infer regulators of mRNA 3’ end processing in glioblastoma

in RNA Networks and Biology

Aleksei Mironov
Lorenzo Franchitti
Shreemoyee Ghosh
Marie-Francoise Ritz
Gregor Hutter
Michele De Bortoli
Mihaela Zavolan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1363933

2,685 views
1 citation

Original Research

Published on 12 Aug 2024

The downregulation of tight junction proteins and pIgR in the colonic epithelium causes the susceptibility of EpCAM+/− mice to colitis and gut microbiota dysbiosis

in Cellular Biochemistry

Ya Nie
Ting Lin
Yanhong Yang
Wanwan Liu
Qing Hu
Guibin Chen
Li Huang
Huijuan Wu
Cunjie Kong
Zili Lei

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1442611

2,716 views

Review

Published on 12 Aug 2024

Lipids and α-Synuclein: adding further variables to the equation

in Cellular Biochemistry

Jana Schepers
Timo Löser
Christian Behl

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1455817

2,297 views
1 citation

Editorial

Published on 09 Aug 2024

Editorial: Systems and network approaches to precision medicine and healthcare

in Molecular Diagnostics and Therapeutics

Emma L. Kurnat-Thoma
Cristian Nogales
Sona Vasudevan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1463962

1,165 views
1 citation

Original Research

Published on 09 Aug 2024

Structural modifications and kinetic effects of KRAS interactions with HRAS and NRAS: an in silico comparative analysis of KRAS mutants

in Biological Modeling and Simulation

Isaac Silverman
Michael Gerber
Aaron Shaykevich
Yitzchak Stein
Alexander Siegman
Sanjay Goel
Radhashree Maitra

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1436976

2,300 views
4 citations

Original Research

Published on 09 Aug 2024

Integrated clinical and metabolomic analysis identifies molecular signatures, biomarkers, and therapeutic targets in primary angle closure glaucoma

in Metabolomics

Vishnu Kannan
Sai Krishna Srimadh Bhagavatham
Rajesh Babu Dandamudi
Haripriya Kunchala
Sivateja Challa
Abdulrahman I. Almansour
Ashish Pargaonkar
Sujith Kumar Pulukool
Anuj Sharma
Venketesh Sivaramakrishnan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1421030

2,020 views

Original Research

Published on 08 Aug 2024

Revealing the regulation of allergic asthma airway epithelial cell inflammation by STEAP4 targeting MIF through machine learning algorithms and single-cell sequencing analysis

in Molecular Diagnostics and Therapeutics

Lu Qiao
Shi-meng Li
Jun-nian Liu
Hong-lei Duan
Xiao-feng Jiang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1427352

4,806 views
2 citations

Original Research

Published on 08 Aug 2024

A novel mitochondria-related algorithm for predicting the survival outcomes and drug sensitivity of patients with lung adenocarcinoma

in Molecular Diagnostics and Therapeutics

Xianqiao Wu
Hang Chen
Zhen Ge
Binyu Luo
Hanbo Pan
Yiming Shen
Zuorun Xie
Chengwei Zhou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1397281

1,266 views

Original Research

Published on 08 Aug 2024

Longitudinal evaluation of manufacturer-specific differences for high-sensitive CRP EQA results

in Molecular Diagnostics and Therapeutics

Nathalie Weiss
Laura Vierbaum
Marcel Kremser
Anne Kaufmann-Stoeck
Silke Kappler
Silvia Ballert
Kathrin Kabrodt
Klaus-Peter Hunfeld
Ingo Schellenberg

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1401405

1,387 views

Original Research

Published on 07 Aug 2024

Discovery of an 8-oxoguanine regulator PCBP1 inhibitor by virtual screening and its synergistic effects with ROS-modulating agents in pancreatic cancer

in Biological Modeling and Simulation

Kexiong Qiao
Chengjie Xu
Chaolei Zhang
Qianqian Wang
Jun Jiang
Zongrong Chen
Liangjing Zhou
Shengnan Jia
Liping Cao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1441550

2,005 views
2 citations

Original Research

Published on 07 Aug 2024

Pan-cancer analysis and single-cell analysis reveals FAM110B as a potential target for survival and immunotherapy

in Molecular Diagnostics and Therapeutics

Yuwei Li
Xiaoxi Li
Bihua Wu
Shuangyan Su
Yunpeng Su
Le Guo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1424104

2,831 views
1 citation

Mini Review

Published on 06 Aug 2024

RBPs: an RNA editor’s choice

in RNA Networks and Biology

Ivo Fierro-Monti

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1454241

3,202 views
2 citations

Original Research

Published on 06 Aug 2024

The clinical significance of endoplasmic reticulum stress related genes in non-small cell lung cancer and analysis of single nucleotide polymorphism for CAV1

in Molecular Diagnostics and Therapeutics

Shuang Li
Junting Chen
Baosen Zhou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1414164

1,422 views
2 citations

Review

Published on 06 Aug 2024

From haystack to high precision: advanced sequencing methods to unraveling circulating tumor DNA mutations

in Molecular Diagnostics and Therapeutics

Tamires Ferreira da Silva
Juscelino Carvalho de Azevedo
Eliel Barbosa Teixeira
Samir Mansour Moraes Casseb
Fabiano Cordeiro Moreira
Paulo Pimentel de Assumpção
Sidney Emanuel Batista dos Santos
Danielle Queiroz Calcagno

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1423470

2,230 views
2 citations

Original Research

Published on 05 Aug 2024

Single-sample gene set enrichment analysis reveals the clinical implications of immune-related genes in ovarian cancer

in Molecular Diagnostics and Therapeutics

Weiwei Gong
Mingqin Kuang
Hongxi Chen
Yiheng Luo
Keli You
Bin Zhang
Yueyang Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1426274

2,135 views

Original Research

Published on 05 Aug 2024

Molecular dynamic simulation reveals the inhibiting impact of Rhein on wild-type and P29S-mutated Rac1

in Biological Modeling and Simulation

Negar Etebar
Seyed Hootan Hamidi
Saghi Naderpour
Omar Abouali
Seyedeh Harir Hamidi
Behnam Hajipour-Verdom
Alireza Zali
Mozhgan Alipour
Milad Rahimzadegan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1414197

1,555 views