Frontiers in Molecular Biosciences | Protein Biochemistry for Basic and Applied Sciences

Original Research

Published on 06 Oct 2021

Characterization of the Cancer-Associated Meprin Βeta Variants G45R and G89R

in Protein Biochemistry for Basic and Applied Sciences

Antonin Gellrich
Franka Scharfenberg
Florian Peters
Martin Sammel
Ole Helm
Fred Armbrust
Frederike Schmidt
Juliane Lokau
Christoph Garbers
Susanne Sebens

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.702341

3,941 views
5 citations

Original Research

Published on 07 Sep 2021

A New Subfamily of Glycoside Hydrolase Family 30 with Strict Xylobiohydrolase Function

in Protein Biochemistry for Basic and Applied Sciences

Casey Crooks
Nathan J. Bechle
Franz J. St John

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.714238

3,771 views
16 citations

Mini Review

Published on 30 Aug 2021

Extracellular Matrix Enzymes and Immune Cell Biology

in Protein Biochemistry for Basic and Applied Sciences

Meagan McMahon
Siying Ye
Jess Pedrina
Daniel Dlugolenski
John Stambas

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.703868

9,088 views
47 citations

Review

Published on 16 Aug 2021

NAD+ Degrading Enzymes, Evidence for Roles During Infection

in Protein Biochemistry for Basic and Applied Sciences

Arnold Tan
Craig L. Doig

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.697359

14,216 views
19 citations

Review

Published on 11 Aug 2021

Multifunctional Fructose 1,6-Bisphosphate Aldolase as a Therapeutic Target

in Protein Biochemistry for Basic and Applied Sciences

David B. Pirovich
Akram A. Da’dara
Patrick J. Skelly

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.719678

34,097 views
92 citations

Original Research

Published on 30 Jul 2021

Molecular and Cellular Studies Reveal Folding Defects of Human Ornithine Aminotransferase Variants Associated With Gyrate Atrophy of the Choroid and Retina

in Protein Biochemistry for Basic and Applied Sciences

Riccardo Montioli
Giada Sgaravizzi
Maria Andrea Desbats
Silvia Grottelli
Carla Borri Voltattorni
Leonardo Salviati
Barbara Cellini

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.695205

3,895 views
7 citations

Mini Review

Published on 29 Jul 2021

Sialidase and Sialyltransferase Inhibitors: Targeting Pathogenicity and Disease

in Protein Biochemistry for Basic and Applied Sciences

William H. D. Bowles
Tracey M. Gloster

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.705133

15,729 views
44 citations

Original Research

Published on 26 Jul 2021

Malate-Aspartate Shuttle Plays an Important Role in LPS-Induced Neuroinflammation of Mice Due to its Effect on STAT3 Phosphorylation

in Protein Biochemistry for Basic and Applied Sciences

Cuiyan Zhou
Wangsong Shang
Shan-Kai Yin
Haibo Shi
Weihai Ying

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.655687

6,479 views
12 citations

Review

Published on 08 Jul 2021

A Novel NAD Signaling Mechanism in Axon Degeneration and its Relationship to Innate Immunity

in Protein Biochemistry for Basic and Applied Sciences

Eleanor L. Hopkins
Weixi Gu
Bostjan Kobe
Michael P. Coleman

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.703532

19,230 views
44 citations

Original Research

Published on 06 Jul 2021

Nicotinamide Mononucleotide Alleviates LPS-Induced Inflammation and Oxidative Stress via Decreasing COX-2 Expression in Macrophages

in Protein Biochemistry for Basic and Applied Sciences

Jing Liu
Zhaoyun Zong
Wenhao Zhang
Yuling Chen
Xueying Wang
Jie Shen
Changmei Yang
Xiaohui Liu
Haiteng Deng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.702107

17,204 views
44 citations

Mini Review

Published on 05 Jul 2021

Targeting the Host Response: Can We Manipulate Extracellular Matrix Metalloproteinase Activity to Improve Influenza Virus Infection Outcomes?

in Protein Biochemistry for Basic and Applied Sciences

Jess Pedrina
John Stambas

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.703456

4,327 views
1 citation

Original Research

Published on 05 Jul 2021

Biochemical and Phylogenetic Characterization of a Novel NADP+-Specific Isocitrate Dehydrogenase From the Marine Microalga Phaeodactylum tricornutum

in Protein Biochemistry for Basic and Applied Sciences

Shiping Huang
Jiaxin Zhao
Wenjing Li
Peng Wang
Zhenglian Xue
Guoping Zhu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.702083

3,777 views
11 citations

Technology and Code

Published on 01 Jul 2021

PPI-MASS: An Interactive Web Server to Identify Protein-Protein Interactions From Mass Spectrometry-Based Proteomics Data

in Protein Biochemistry for Basic and Applied Sciences

Mariela González-Avendaño
Simón Zúñiga-Almonacid
Ian Silva
Boris Lavanderos
Felipe Robinson
Roberto Rosales-Rojas
Fabio Durán-Verdugo
Wendy González
Mónica Cáceres
Oscar Cerda

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.701477

7,873 views
4 citations

Review

Published on 29 Jun 2021

Regulation of ADAMTS Proteases

in Protein Biochemistry for Basic and Applied Sciences

Keron W. J. Rose
Nandaraj Taye
Stylianos Z. Karoulias
Dirk Hubmacher

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.701959

14,553 views
88 citations

Review

Published on 23 Jun 2021

Human D-aspartate Oxidase: A Key Player in D-aspartate Metabolism

in Protein Biochemistry for Basic and Applied Sciences

Loredano Pollegioni
Gianluca Molla
Silvia Sacchi
Giulia Murtas

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.689719

6,738 views
25 citations

Brief Research Report

Published on 10 Jun 2021

Thermodynamic Analysis for Binding of 4-O-β-tri-N-acetylchitotriosyl Moranoline, a Transition State Analogue Inhibitor for Hen Egg White Lysozyme

in Protein Biochemistry for Basic and Applied Sciences

Makoto Ogata
Tamo Fukamizo
Takayuki Ohnuma

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.654706

2,861 views
6 citations

Original Research

Published on 28 May 2021

Exploring the Binding Interaction of Raf Kinase Inhibitory Protein With the N-Terminal of C-Raf Through Molecular Docking and Molecular Dynamics Simulation

in Protein Biochemistry for Basic and Applied Sciences

Shraddha Parate
Shailima Rampogu
Gihwan Lee
Jong Chan Hong
Keun Woo Lee

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.655035

8,605 views
14 citations

Review

Published on 28 May 2021

Role of Fibrinolytic Enzymes in Anti-Thrombosis Therapy

in Protein Biochemistry for Basic and Applied Sciences

Farwa Altaf
Shourong Wu
Vivi Kasim

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.680397

44,703 views
91 citations

Editorial

Published on 26 May 2021

Editorial: Mechanisms of Fluorescent Proteins

in Protein Biochemistry for Basic and Applied Sciences

Chong Fang
Mikhail Drobizhev
Ho Leung Ng
Periklis Pantazis

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.701523

4,673 views
2 citations

Original Research

Published on 24 May 2021

Glycosylation at Asn254 Is Required for the Activation of the PDGF-C Protein

in Protein Biochemistry for Basic and Applied Sciences

Wenjie Hu
Ruting Zhang
Wei Chen
Dongyue Lin
Kun Wei
Jiahui Li
Bo Zhang
Xuri Li
Zhongshu Tang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.665552

3,847 views
3 citations

Brief Research Report

Published on 19 May 2021

A Novel GH Family 20 β-N-acetylhexosaminidase With Both Chitosanase and Chitinase Activity From Aspergillus oryzae

in Protein Biochemistry for Basic and Applied Sciences

Tianle Qu
Chunyue Zhang
Zhen Qin
Liqiang Fan
Lihua Jiang
Liming Zhao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.684086

4,376 views
18 citations

Original Research

Published on 19 May 2021

NAD+ Metabolism, Metabolic Stress, and Infection

in Protein Biochemistry for Basic and Applied Sciences

Benjamin Groth
Padmaja Venkatakrishnan
Su-Ju Lin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.686412

13,297 views
33 citations

Original Research

Published on 14 May 2021

NBD-Based Environment-Sensitive Fluorescent Probes for the Human Ether-a-Go-Go–Related Gene Potassium Channel

in Protein Biochemistry for Basic and Applied Sciences

Qi Li
Lijuan Chai
Gaopan Dong
Xiaomeng Zhang
Lupei Du

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.666605

5,030 views
8 citations

Review

Published on 30 Apr 2021

ADAMTS-12: Functions and Challenges for a Complex Metalloprotease

in Protein Biochemistry for Basic and Applied Sciences

Yamina Mohamedi
Tania Fontanil
Santiago Cal
Teresa Cobo
Álvaro J. Obaya

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2021.686763

7,686 views
21 citations

283 articles

articles

Characterization of the Cancer-Associated Meprin Βeta Variants G45R and G89R

A New Subfamily of Glycoside Hydrolase Family 30 with Strict Xylobiohydrolase Function

Extracellular Matrix Enzymes and Immune Cell Biology

NAD+ Degrading Enzymes, Evidence for Roles During Infection

Multifunctional Fructose 1,6-Bisphosphate Aldolase as a Therapeutic Target

Molecular and Cellular Studies Reveal Folding Defects of Human Ornithine Aminotransferase Variants Associated With Gyrate Atrophy of the Choroid and Retina

Sialidase and Sialyltransferase Inhibitors: Targeting Pathogenicity and Disease

Malate-Aspartate Shuttle Plays an Important Role in LPS-Induced Neuroinflammation of Mice Due to its Effect on STAT3 Phosphorylation

A Novel NAD Signaling Mechanism in Axon Degeneration and its Relationship to Innate Immunity

Nicotinamide Mononucleotide Alleviates LPS-Induced Inflammation and Oxidative Stress via Decreasing COX-2 Expression in Macrophages

Targeting the Host Response: Can We Manipulate Extracellular Matrix Metalloproteinase Activity to Improve Influenza Virus Infection Outcomes?

Biochemical and Phylogenetic Characterization of a Novel NADP+-Specific Isocitrate Dehydrogenase From the Marine Microalga Phaeodactylum tricornutum

PPI-MASS: An Interactive Web Server to Identify Protein-Protein Interactions From Mass Spectrometry-Based Proteomics Data

Regulation of ADAMTS Proteases

Human D-aspartate Oxidase: A Key Player in D-aspartate Metabolism

Thermodynamic Analysis for Binding of 4-O-β-tri-N-acetylchitotriosyl Moranoline, a Transition State Analogue Inhibitor for Hen Egg White Lysozyme

Exploring the Binding Interaction of Raf Kinase Inhibitory Protein With the N-Terminal of C-Raf Through Molecular Docking and Molecular Dynamics Simulation

Role of Fibrinolytic Enzymes in Anti-Thrombosis Therapy

Editorial: Mechanisms of Fluorescent Proteins

Glycosylation at Asn254 Is Required for the Activation of the PDGF-C Protein

A Novel GH Family 20 β-N-acetylhexosaminidase With Both Chitosanase and Chitinase Activity From Aspergillus oryzae

NAD+ Metabolism, Metabolic Stress, and Infection

NBD-Based Environment-Sensitive Fluorescent Probes for the Human Ether-a-Go-Go–Related Gene Potassium Channel

ADAMTS-12: Functions and Challenges for a Complex Metalloprotease